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CompletedNCT07810049Updated Sep 9, 2026

Synchronous Bilateral Talc Pleurodesis

An observational study in Bilateral Pleural Effusion and Pleurodesis, sponsored by European Institute of Oncology. Completed at 1 site in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-09.

Sponsored by European Institute of Oncology · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
31
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 14 studies in Lung Neoplasms by European Institute of Oncology — 9 open to participants now, 9 under way, none of them phase 3. Lung Neoplasms · European Institute of Oncology.

Enrollment
10th of 11
31 · median 200
Started
1998
the only one that year
Other kind
3 of 14
1 open now
Registered
12th of 14
by date

Among the 14 studies in Lung Neoplasms by European Institute of Oncology, this one is the 10th largest by enrollment of the 11 observational ones, is the only one that started in 1998, is one of 3 of another kind, and was the 12th registered.

By phase

14 studies; the count open now beside each. This study's row is marked.

Observational8 · 8 open
Other kindthis study3 · 1 open
Phase 32 · 0 open
No phase1 · 0 open

By the year they started

First in 1994; this study’s year is marked. 1 started in 1998.

Size and results

Median enrollment 320 across the 3 interventional studies, 200 across the 11 observational. Of the 3 that completed or were terminated, 0 (0%) have results posted.

Watch this landscapeDownload CSVWith an account: a weekly mail of what changed among 14 studies in Lung Neoplasms by European Institute of Oncology, or all of them as a file.
02

Study summary

Investigate feasibility of synchronous bilateral talc pleurodesis for malignant bilateral pleural effusions

03

Conditions studied

  • Bilateral Pleural Effusion
  • Pleurodesis

Keywords

  • lung cancer
  • malignant pleural effusion
  • pleurodesis
  • bilateral pleural effusion
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patient diagnosed with malignant pleural bilateral effusion

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age ≥ 18 year-old
  • Patients undergoing synchronous bilateral talc pleurodesis
  • Diagnosis of malignant bilateral pleural effusions
  • Surgical resection between 1998 and September 2025

Exclusion criteria

Exclusion Criteria:

  • Other type of surgery
  • Lack of consent to research
  • Other type of diagnosis (e.g. viral disease)
05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
31 participants (actual)
Patient registry
No

Groups and cohorts

  • Patient diagnosed of malignant bilateral pleural effusions

    Patient diagnosed of malignant bilateral pleural effusions that underwent a synchronous bilateral talc pleurodesis

06

What researchers measure

Primary outcomes

  1. postoperative mortality

    Evaluation of postoperative complications occurred after talc pleurodesis.

    Time frame: 35 years

  2. postoperative morbidity

    Evaluation of postoperative complications occurred after talc pleurodesis.

    Time frame: 35 years

07

Study locations

1 site
  • Istituto Europeo di Oncologia
    Milan, Italy
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 9, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07810049
Responsible party
Sponsor
First posted
Sep 9, 2026
Start date
Jan 1998
Primary completion
Sep 30, 2025
Completion
Sep 30, 2025
Last update
Sep 9, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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