Penile Neoplasms clinical trials
The registry lists 99 studies for Penile Neoplasms across more than 10 countries. 28 are recruiting or about to start. 38 of them are mainly about Penile Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Cancer Institute (NCI) (9) · M.D. Anderson Cancer Center (5) · Sun Yat-sen University (4) · The Netherlands Cancer Institute (4) · UNICANCER (3) · Fudan University (3) · The Affiliated Hospital of Qingdao University (2) · University of Maryland, College Park (2)
What is being tested here
Drugs under test in Penile Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Immune checkpoint inhibitors 9 open · Tyrosine kinase inhibitors (TKIs) 2 open · Antimitotic agents 6 · Alkylating agents 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study) · Phase 3 · Institute of Cancer Research, United Kingdom
- Jul 2027A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males · Phase 3 · Shanghai Bovax Biotechnology Co., Ltd.
- Nov 2026Study of the Combination Dostarlimab With Niraparib In Patients With Penile Carcinoma · H. Lee Moffitt Cancer Center and Research Institute
- Dec 2026Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma · SCG Cell Therapy Pte. Ltd.
- Dec 2026Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors · Dana-Farber Cancer Institute
- Dec 2026Multi-cohort, Single-arm Phase II Study of Albumin-paclitaxel, Ifosfamide, and Cisplatin in the Treatment of Rare Advanced Tumors · Fudan University
- Dec 2026A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy · University Health Network, Toronto
- Jan 2027Lymphedema After Urologic Surgery · Vastra Gotaland Region
- Jan 2027E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers · Christian Hinrichs
- Feb 2027Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · National Cancer Institute (NCI)
Who these studies take
Of the 23 Penile Neoplasms studies recruiting now, 18 (78%) set no upper age limit and 2 (9%) stop at 75 or younger. 2 (9%) take children under 18. 0 (0%) are for women only and 9 (39%) for men only; 2 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 2 (9%) |
| 18 | 13 (57%) | 22 (96%) |
| 30 | 14 (61%) | 23 (100%) |
| 40 | 14 (61%) | 23 (100%) |
| 50 | 14 (61%) | 23 (100%) |
| 65 | 14 (61%) | 23 (100%) |
| 75 | 13 (57%) | 22 (96%) |
| 85 | 11 (48%) | 19 (83%) |
Across all 99 studies, recruiting or not: 15% stop at 75 or younger and 4% at 65; 12% take children; 2% are for women only and 39% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Penile Neoplasms studies take
Of 28 phase 2 interventional studies under Penile Neoplasms, half reached primary completion within 63 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 63 mo35–… · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 99. Browse all 99 → or search them.
- Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary TumorsRecruitingNCT03866382Phase 22 countries
- Sacituzumab Tirumotecan Plus Toripalimab for Advanced Penile Cancer After Platinum ChemotherapyNot yet recruitingNCT07907861Phase 21 country
- E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated CancersRecruitingNCT05686226Phase 21 country
- E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated CancersRecruitingNCT05639972Phase 1/21 country
- A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract MalignanciesRecruitingNCT049231781 country
- DEfeating PEnile CAncer-2RecruitingNCT07378670Not applicable1 country
- A Study of Becotatug Vedotin Combined With Pucotenlimab in the Treatment of EGFR-Positive Advanced Penile CancerRecruitingNCT07497919Phase 21 country
- Neoadjuvant Pucotenlimab and Becotatug Vedotin for Locally Advanced Penile CancerNot yet recruitingNCT07767266Phase 21 country
- EGFR-ADC (Becotatug Vedotin) Combined With PD-1 Inhibitor (Pucotenlimab) in Neoadjuvant Treatment of Advanced Penile CancerRecruitingNCT07518979Phase 21 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the PenisRecruitingNCT06104618Phase 21 country
- QL1706 Plus Lenvatinib in Previously Treated Penile CancerRecruitingNCT07384416Phase 21 country
- MRG003 Plus HX008 as First-Line Treatment for EGFR-Positive Locally Advanced or Metastatic Penile Squamous Cell CarcinomaRecruitingNCT07054307Phase 11 country
- Lymphedema After Urologic SurgeryRecruitingNCT052643371 country
- Carboplatin/Paclitaxel + Pembrolizumab for Locoregionally Advanced Penile CancerRecruitingNCT06353906Phase 22 countries
- Study of the Combination Dostarlimab With Niraparib In Patients With Penile CarcinomaRecruitingNCT05526989Phase 21 country
- Ivonescimab in the Treatment of Multiple Advanced TumorsRecruitingNCT06683846Phase 21 country
- A PHASE II, RANDOMIZED STUDY TO ASSESS MAINTENANCE THERAPY WITH CEMIPLIMAB VERSUS BEST SUPPORTIVE CARE AFTER 1ST LINE PLATINUM-BASED CHEMOTHERAPY IN ADVANCED/RECURRENT PENILE CANCERNot yet recruitingNCT07101822Phase 21 country
- FIH, Bispecific CD276xCD3 Antibody CC-3 in Patients With Colorectal CancerRecruitingNCT05999396Phase 11 country
- Multi-cohort, Single-arm Phase II Study of Albumin-paclitaxel, Ifosfamide, and Cisplatin in the Treatment of Rare Advanced TumorsRecruitingNCT06684327Phase 21 country
- Prediction of Local Recurrence and Its Impact on Long-term Outcomes After Low-risk Glans-sparing Surgery for Penile Squamous Cell CarcinomaEnrolling by invitationNCT065655851 country
- SCG142 TCR-T Cells for Human Papillomavirus-Associated CarcinomasRecruitingNCT06544720Phase 11 country
- Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive CarcinomaNot yet recruitingNCT06505551Phase 1/2
- The Role of Functional Magnetic Resonance Imaging in Preoperative Assessment of Primary Penile CarcinomaRecruitingNCT054472731 country
- HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid TumorRecruitingNCT05787535Phase 11 country
- HRYZ-T101 Injection for HPV18 Positive Solid TumorRecruitingNCT05952947Phase 11 country
- The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological TelesurgeryRecruitingNCT05739812Not applicable1 country
- Development of Diagnostics and Treatment of Urological CancersRecruitingNCT02994758Not applicable1 country
- Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic CancersActive, not recruitingNCT07118176Phase 11 country
- Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary TumorsActive, not recruitingNCT02496208Phase 11 country
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 21 country
- TIP Regimen Combined With Toripalimab Neoadjuvant Therapy for Locally Advanced Penile CancerCompletedNCT06415318Phase 21 country
- HARE-40: HPV Anti-CD40 RNA vaccinECompletedNCT03418480Phase 1/21 country
- Linking In With Advice and Supports for Men Impacted by Metastatic CancerActive, not recruitingNCT05946993Not applicable1 country
- A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of InterestCompletedNCT05899361Not applicable1 country
- A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersCompletedNCT04708470Phase 1/21 country
- International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)Active, not recruitingNCT02305654Phase 32 countries
- Assessment of Patient Experience and Needs for Patients Undergoing Invasive Inguinal Lymph Node Procedures for Penile CancerSuspendedNCT058420311 country
- Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial CancerActive, not recruitingNCT04491942Phase 12 countries
- Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary TumorsActive, not recruitingNCT03333616Phase 21 country
- Validation of ICG-99mTc-nanoscan as Hybrid Tracer for Sentinel Node BiopsyCompletedNCT06666634Not applicable1 country
- Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are MetastaticActive, not recruitingNCT02721732Phase 21 country
- A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based ChemotherapyActive, not recruitingNCT03391479Phase 21 country
- Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)CompletedNCT054614301 country
- Contemporary Characteristics of Penile CancerTerminatedNCT049968491 country
- Enhanced Assistance During Radiotherapy for Unmet Essential NeedsCompletedNCT06582849Not applicable1 country
- Evaluation of Lymphadenectomy and Chemotherapy TIP on Inguinal Lymph Nodes in Squamous Cell Carcinoma of the PenisActive, not recruitingNCT02817958Phase 21 country
- Efficacy of INCMGA00012 in Penile Squamous Cell Carcinoma (ORPHEUS)CompletedNCT04231981Phase 22 countries
- VideoEndoscopic Radical Inguinal Lymphadenectomy for Penile CancerActive, not recruitingNCT05592639Not applicable1 country
- Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different LocationsCompletedNCT04357873Phase 21 country