Otitis Externa clinical trials
The registry lists 22 studies for Otitis Externa across more than 10 countries. 1 are recruiting or about to start. 20 of them are mainly about Otitis Externa (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-13.
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Who runs them
Alcon Research (3) · Otic Pharma (3) · Shire (2) · Otonomy, Inc. (2) · Salvat (1) · Par Pharmaceutical, Inc. (1) · Exela Pharma Sciences, LLC. (1) · Farmoquimica S.A. (1)
What is being tested here
Drugs under test in Otitis Externa studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Nigella sativa oil | 1 | 0 | 1 |
| Ciprofloxacin | 0 | 3 | 6 |
| Dexamethasone | 0 | 2 | 2 |
| Hydrocortisone | 0 | 1 | 1 |
| Moxifloxacin | 0 | 1 | 1 |
| Dexamethasone phosphate | 0 | 1 | 1 |
| Diclofenac | 0 | 0 | 1 |
Drug classes tested here Corticosteroids 3
Who these studies take
Of the 1 Otitis Externa studies recruiting now, 1 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 1 (100%) | 1 (100%) |
| 30 | 1 (100%) | 1 (100%) |
| 40 | 1 (100%) | 1 (100%) |
| 50 | 1 (100%) | 1 (100%) |
| 65 | 1 (100%) | 1 (100%) |
| 75 | 1 (100%) | 1 (100%) |
| 85 | 1 (100%) | 1 (100%) |
Across all 22 studies, recruiting or not: 14% stop at 75 or younger and 5% at 65; 55% take children; 0% are for women only and 0% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 22 of 22. search them.
- Nigella Sativa Oil for Eczematous Otitis ExternaRecruitingNCT07525505Not applicable1 country
- Efficacy and Safety of Ciprofloxacin Plus Fluocinolone Acetonide Otic Solution in the Treatment of Acute Otitis ExternaCompletedNCT04636957Phase 31 country
- 18F-FDG Tomography and Labeled Leukocyte ScintigraphyCompletedNCT059947681 country
- Non Interventional Clinical Investigation of Ectoin Ear Spray in Skin Treatment of Outer Ear Canal IrritationsCompletedNCT025587381 country
- Performance and Safety of Otinova® Ear SprayTerminatedNCT05370209Not applicable1 country
- Comparative Efficacy and Safety of Ciprofloxacin 0.3% and Dexamethasone 0.1% in Acute Otitis ExternaCompletedNCT02216071Phase 32 countries
- FST-201 In The Treatment of Acute Fungal Otitis ExternaTerminatedNCT00945646Phase 31 country
- FST-201 In The Treatment of Acute Otitis ExternaTerminatedNCT00945802Phase 31 country
- Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Acute Otitis ExternaCompletedNCT03196973Phase 31 country
- Phase 3 Study of OTO-201 in Acute Otitis ExternaCompletedNCT02801370Phase 32 countries
- OTO-201 for the Treatment of Otitis ExternaCompletedNCT02511561Phase 21 country
- A Bioequivalence Study of Two Ciprofloxacin/Dexamethasone Formulations in Patients With Otitis ExternaTerminatedNCT01910155Phase 32 countries
- Topical Voltaren in Otitis ExternaTerminatedNCT00523120Phase 21 country
- A Comparative Study Between Two Formulations of the Ciprofloxacin Hydrochloride + Hydrocortisone Otic SuspensionCompletedNCT00980876Phase 31 country
- Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis ExternaCompletedNCT01535599Phase 3
- Safety and Efficacy Evaluation of Topical AL-60371 Otic Suspension, 0.3% in the Treatment of Acute Otitis ExternaCompletedNCT01535560Phase 3
- A Study of DPK-060 to Investigate Clinical Safety and Efficacy in Patients With Acute External OtitisCompletedNCT01447017Phase 21 country
- Study of Ear Comfort Ear Drops to Treat AOE Cases Compared to DexOtic & Otidin(R)Status unknownNCT01584271Phase 21 country
- A Phase III Study of an Otic Formulation in Acute Otitis ExternaCompletedNCT00750633Phase 3
- Efficacy and Safety of Once-Daily Ciprodexa Otic Foam Compared to Twice-daily Ciprodex Ear Drops in Acute Otitis ExternaCompletedNCT01359098Phase 21 country
- Safety and Efficacy of Once-Daily Dosing of FoamOtic Cipro Compared to Twice-Daily Dosing of Ciloxan Ear Drops in Patients With Acute External OtitisCompletedNCT01157819Phase 21 country
- Safety and Efficacy Study of Foam Otic Cipro Compared to a Standard Solution ( Ciloxan - Alcon Labs ) to Treat Acute Otitis ExternaCompletedNCT00872209Phase 1/21 country