Nocturnal Enuresis clinical trials
The registry lists 105 studies for Nocturnal Enuresis across more than 10 countries. 22 are recruiting or about to start. 80 of them are mainly about Nocturnal Enuresis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
University of Aarhus (7) · Cairo University (6) · Ferring Pharmaceuticals (5) · InnoCon Medical (4) · C. R. Bard (4) · Rabin Medical Center (3) · Menoufia University (3) · Mansoura University (3)
What is being tested here
Drugs under test in Nocturnal Enuresis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10, phase 3 first
- Nov 2026Efficacy of Mirabegron for Treatment of Non-monosymptomatic Nocturnal Enuresis in Children · Phase 3 · Menoufia University
- Dec 2026Optimal Pulse Width Used in Transcutaneous Electrical Nerve Stimulation for Treating Nocturnal Enuresis in Children · Albany Medical College
- Jan 2027Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD) · InnoCon Medical
- Jan 2027Aerobic Exercise Added to Diaphragmatic Breathing for Nocturnal Enuresis in Overweight and Obese Children · Hungarian University of Sports Science
- Jan 2027TENS in Nocturnal Enuresis · Suez Canal University
- May 2027Causes and Types of Nocturnal Enuresis in Children · Assiut University
- May 2027Bedtime Device Restriction and Desmopressin in PMNE. · Al-Azhar University
- May 2027Adjustable Continence Therapy (ACT) for the Treatment of Female SUI · Uromedica
- Jun 2027Potential Adjuvant Therapies for Children With Primary Nocturnal Enuresis · Cairo University
- Jun 2027UCon Treatment of Overactive Bladder (OAB) in Males · InnoCon Medical
Who these studies take
Of the 14 Nocturnal Enuresis studies recruiting now, 5 (36%) set no upper age limit and 9 (64%) stop at 75 or younger. 8 (57%) take children under 18. 4 (29%) are for women only and 1 (7%) for men only; 2 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (57%) | 7 (50%) |
| 18 | 6 (43%) | 4 (29%) |
| 30 | 4 (29%) | 2 (14%) |
| 40 | 4 (29%) | 2 (14%) |
| 50 | 4 (29%) | 2 (14%) |
| 65 | 5 (36%) | 3 (21%) |
| 75 | 4 (29%) | 3 (21%) |
| 85 | 4 (29%) | 3 (21%) |
Across all 105 studies, recruiting or not: 75% stop at 75 or younger and 72% at 65; 76% take children; 13% are for women only and 6% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Nocturnal Enuresis studies take
Of 41 interventional studies with no phase under Nocturnal Enuresis, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo9–49 · 41 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Results posted1
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 105. Browse all 105 → or search them.
- Safety and Performance of UCon Patch ElectrodeRecruitingNCT06754189Not applicable1 country
- UCon Treatment of Overactive Bladder (OAB) in MalesRecruitingNCT05874375Not applicable1 country
- Effectiveness of Individualized Pelvic Floor Muscle Rehabilitation in Addition to Standard Urotherapy and Alarm Therapy in Children With Primary Monosymptomatic Nocturnal EnuresisRecruitingNCT07890194Not applicable1 country
- Potential Adjuvant Therapies for Children With Primary Nocturnal EnuresisNot yet recruitingNCT07876947Not applicable
- Adjustable Continence Therapy (ACT) for the Treatment of Female SUIRecruitingNCT04248283Not applicable2 countries
- Sleep in Children Placed in Out-of-home CareNot yet recruitingNCT07820683Not applicable
- Bedtime Device Restriction and Desmopressin in PMNE.RecruitingNCT07776977Not applicable1 country
- TENS in Nocturnal EnuresisNot yet recruitingNCT07594353Not applicable
- Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy ChildrenRecruitingNCT05989646Not applicable1 country
- Causes and Types of Nocturnal Enuresis in ChildrenNot yet recruitingNCT07508111
- Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)RecruitingNCT06091566Not applicable1 country
- Study of Transition in Real-life Experiences Affecting Micturition and Well-being in Adolescent YearsEnrolling by invitationNCT073398651 country
- The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.RecruitingNCT072957821 country
- Optimal Pulse Width Used in Transcutaneous Electrical Nerve Stimulation for Treating Nocturnal Enuresis in ChildrenRecruitingNCT06135311Not applicable1 country
- Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNERecruitingNCT07199894Phase 31 country
- A Cohort Study on Treating Primary Nocturnal Enuresis by Regulating Central-Peripheral Circadian RhythmNot yet recruitingNCT07003126Not applicable1 country
- Aromatherapy Versus DietNot yet recruitingNCT06853379Not applicable
- The Role of Timed Awakening in Treatment of EnuresisNot yet recruitingNCT06586476Not applicable1 country
- Desmopressin Monotherapy for Monosymptomatic Nocturnal EnuresisRecruitingNCT06285006Not applicable1 country
- Think Dry: Optimalisation of Diagnostic Process of Urinary Incontinence in Older PeopleRecruitingNCT040947531 country
- Effect of Laser Acupuncture for Treating Monosymptomatic Nocturnal Enuresis in Adolescent FemalesRecruitingNCT05399173Not applicable1 country
- Mirabegron 25 mg for Treatment of Primary Nocturnal EnuresisRecruitingNCT05617664Not applicable1 country
- Using Tele-rehabilitation on Management of Pediatric Nocturnal EnuresisCompletedNCT07108062Not applicable1 country
- Aerobic Exercise Added to Diaphragmatic Breathing for Nocturnal Enuresis in Overweight and Obese ChildrenActive, not recruitingNCT07930351Not applicable1 country
- Effectiveness of Multimodal Pelvic Floor Rehabilitation Program in Children With Different Types of Urinary IncontinenceCompletedNCT06231394Not applicable1 country
- This Study Will Collect Clinical and Patient Reported Satisfaction Data From Males Requiring Urine Output Management Overnight in the Home Setting.CompletedNCT06850259Not applicable1 country
- Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress IncontinenceActive, not recruitingNCT03104517Phase 32 countries
- Efficacy of Mirabegron for Treatment of Non-monosymptomatic Nocturnal Enuresis in ChildrenActive, not recruitingNCT07398261Phase 31 country
- Empowering Mothers of Children With Nocturnal Enuresis to Improve Knowledge, Practices, and Quality of LifeCompletedNCT07753304Not applicable1 country
- An Evaluation of the PureWick™ Male External Catheter Versus an Established Comparator Overnight in the Home Setting for Incontinence in Adult MalesCompletedNCT07282860Not applicable1 country
- Adverse Outcomes Following Female Genital Fistula RepairActive, not recruitingNCT054379391 country
- Bladder Wall Thickness for Treatment Response in Children With Lower Urinary Tract Dysfunction or EnuresisActive, not recruitingNCT076569351 country
- TENS Treatment for BedwettingCompletedNCT04313192Not applicable1 country
- Vitamin D Versus Desmopressin Versus Combination Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis and Vitamin D DeficiencyCompletedNCT07292753Not applicable1 country
- Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting AlarmTerminatedNCT05214131Not applicable1 country
- Hidden Link Between Meatal Stenosis and Primary Nocturnal Enuresis in ChildrenCompletedNCT074246511 country
- Ginkgo Biloba vs Desmopressin in Treatment of Children With Monosymptomatic Nocturnal EnuresisCompletedNCT06771128Not applicable1 country
- This Study Will Collect Clinical and Patient Reported Experience Data From Participants Requiring Urine Output Management Overnight in the Home Setting.CompletedNCT06666426Not applicable1 country
- PureWick™ France and U.S. At-Home Pilot StudyCompletedNCT05710718Not applicable1 country
- Uroflowmetry and Nocturnal EnuresisActive, not recruitingNCT070286451 country
- The Behavioral Therapy for Primary Monosymptomatic Nocturnal EnuresisCompletedNCT070153201 country
- Comparative Study of the Efficacy of TENS Versus Placebo in Isolated Primary EnuresisCompletedNCT04413461Not applicable1 country
- Effect of Pilates and Kegel Exercises During PregnancyCompletedNCT068695381 country
- Idiopathic Normal Pressure Hydrocephalus: Focus on Imaging and Clinical Symptoms.CompletedNCT04808076Not applicable1 country
- Ginko Biloba Versus Desmopressin in Treatment of Children With Monosymptomatic Nocturnal EnuresisCompletedNCT06772584Not applicable1 country
- Effect of Use of DryNites Absorbent Pants on the Rate of Spontaneous Resolution of Paediatric Nocturnal Enuresis (NE)CompletedNCT04620356Not applicable1 country
- Nocturnal Enuresis Symptom ScoreCompletedNCT064889761 country
- Overnight Pant Study for Children With Nocturnal EnuresisCompletedNCT05178641Not applicable1 country
- Japanese Bridging Study of Autologous Muscle Derived Cells Compared to Placebo for Female Urinary Sphincter Repair(JPN1)WithdrawnNCT03997318Phase 3
- Botulinum Neurotoxin Type A (BoNT-A) in Paediatric Non-neurogenic Therapy Resistant Overactive Bladder (OAB)CompletedNCT065693421 country