Nocturia clinical trials
The registry lists 134 studies for Nocturia across more than 10 countries. 22 are recruiting or about to start. 79 of them are mainly about Nocturia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Who runs them
Ferring Pharmaceuticals (19) · Vantia Ltd (10) · University Hospital, Ghent (9) · Serenity Pharmaceuticals, Inc. (6) · InnoCon Medical (4) · Atlanta VA Medical Center (3) · Seoul National University Hospital (3) · University of Pittsburgh (3)
What is being tested here
Drugs under test in Nocturia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Mirabegron | 2 | 3 | 4 |
| Solifenacin | 1 | 4 | 5 |
| Tolterodine | 1 | 1 | 2 |
| Lemborexant | 1 | 0 | 1 |
| Oxybutynin | 1 | 1 | 1 |
| Onabotulinum toxin A | 1 | 0 | 1 |
| Botulinum toxin type A | 1 | 0 | 1 |
| Deamino Arginine Vasopressin | 0 | 16 | 24 |
| VA106483 | 0 | 0 | 6 |
| Fedovapagon | 0 | 1 | 4 |
Drug classes tested here Antimuscarinics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women · Medstar Health Research Institute
- Nov 2026Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital Cancer · Universitaire Ziekenhuizen KU Leuven
- Dec 2026This Research Project Studies the Relationship Between OSA and Nocturia. · University Hospital Ostrava
- Dec 2026Moxibustion for Nocturia · Buddhist Tzu Chi General Hospital
- Jan 2027Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD) · InnoCon Medical
- Feb 2027Low-Intensity Shock Wave Therapy for Refractory Overactive Bladder in Women · Al-Azhar University
- Apr 2027Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis · Wake Forest University Health Sciences
- May 2027Ancillary Nocturnal Urinary Symptoms Analyses for TRIUMPH · University of California, San Francisco
- Jun 2027A Novel Wearable Transcutaneous Tibial Nerve Stimulation (TTNS) Device in the Treatment of Patients With Overactive Bladder (OAB) and Nocturia · Qilu Hospital of Shandong University
- Jun 2027UCon Treatment of Overactive Bladder (OAB) in Males · InnoCon Medical
Who these studies take
Of the 17 Nocturia studies recruiting now, 13 (76%) set no upper age limit and 2 (12%) stop at 75 or younger. 0 (0%) take children under 18. 8 (47%) are for women only and 2 (12%) for men only; 5 (29%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 7 (41%) | 5 (29%) |
| 30 | 8 (47%) | 5 (29%) |
| 40 | 10 (59%) | 6 (35%) |
| 50 | 11 (65%) | 7 (41%) |
| 65 | 15 (88%) | 9 (53%) |
| 75 | 14 (82%) | 9 (53%) |
| 85 | 12 (71%) | 8 (47%) |
Across all 134 studies, recruiting or not: 21% stop at 75 or younger and 16% at 65; 5% take children; 28% are for women only and 22% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Nocturia studies take
Of 34 interventional studies with no phase under Nocturia, half reached primary completion within 17 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 17 mo7–37 · 34 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
Results posted1
Studies
Recruiting first, then most recently updated. Showing 50 of 134. Browse all 134 → or search them.
- Safety and Performance of UCon Patch ElectrodeRecruitingNCT06754189Not applicable1 country
- UCon Treatment of Overactive Bladder (OAB) in MalesRecruitingNCT05874375Not applicable1 country
- Addressing Nocturia in Older Women Utilizing Behavioral Sleep Intervention and Brief MindfulnessRecruitingNCT07760779Not applicable1 country
- Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer.RecruitingNCT05148156Not applicable1 country
- How Well and Safely Does Lemborexant Work for People Who Wake up at Night to Urinate (LENS)Not yet recruitingNCT07840638Phase 41 country
- Ancillary Nocturnal Urinary Symptoms Analyses for TRIUMPHRecruitingNCT07829029Phase 41 country
- Electroacupuncture as a Treatment for Refractory Overactive BladderRecruitingNCT07124390Not applicable1 country
- Multi-center Trial to Improve Nocturia and Sleep in Older AdultsRecruitingNCT06110091Not applicable1 country
- Low-Intensity Shock Wave Therapy for Refractory Overactive Bladder in WomenNot yet recruitingNCT07739550Not applicable1 country
- A Community-based Solution for Nocturia: Integrating Digital Technology and Behavioral InterventionsRecruitingNCT07734207Not applicable1 country
- Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial CystitisRecruitingNCT04734106Early Phase 11 country
- A Pilot Study to Evaluate PureWick for NocturiaRecruitingNCT05090722Not applicable1 country
- A Novel Wearable Transcutaneous Tibial Nerve Stimulation (TTNS) Device in the Treatment of Patients With Overactive Bladder (OAB) and NocturiaNot yet recruitingNCT07635251Not applicable1 country
- Moxibustion for NocturiaRecruitingNCT07598227Not applicable1 country
- Low-Energy Shock Wave Therapy for Overactive Bladder in Women With Metabolic SyndromeRecruitingNCT07563764Not applicable1 country
- Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)RecruitingNCT06091566Not applicable1 country
- The Effect of Nighttime Mirabegron, Solifenacin, Tolterodine, or Oxybutynin on Nocturia, Sexual Function, Autonomic Function, and Lower Urinary Tract Blood Flow Perfusion in Women With Overactive Bladder Syndrome: Randomized Controlled TrialNot yet recruitingNCT07114640Phase 31 country
- Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital CancerRecruitingNCT053003081 country
- This Research Project Studies the Relationship Between OSA and Nocturia.RecruitingNCT062398831 country
- Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Syndrome and Associated Gait Changes in Post-menopausal WomenNot yet recruitingNCT06617676Not applicable
- Effect of Hormonal Replacement Therapy on Nocturia in Postmenopausal WomenRecruitingNCT044338971 country
- Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin ARecruitingNCT04305743Phase 41 country
- APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in WomenActive, not recruitingNCT06797245Not applicable1 country
- This Study Will Collect Clinical and Patient Reported Satisfaction Data From Males Requiring Urine Output Management Overnight in the Home Setting.CompletedNCT06850259Not applicable1 country
- An Acupuncture Study for Prostate Cancer Survivors With Urinary IssuesActive, not recruitingNCT05540392Phase 1/21 country
- Examination of the Effect of Nocturia on Pelvic Floor Symptoms, Sleep Parameters and Quality of Life in Women With Urinary IncontinenceCompletedNCT068668341 country
- Mandibular Advancement Device and Changes in NocturiaCompletedNCT05562388Not applicable1 country
- Effect of Behavioral Sleep Intervention on Lower Urinary Tract Symptoms in Older WomenActive, not recruitingNCT05604222Phase 41 country
- An Evaluation of the PureWick™ Male External Catheter Versus an Established Comparator Overnight in the Home Setting for Incontinence in Adult MalesCompletedNCT07282860Not applicable1 country
- Solifenacin Plus Tadalafil vs Solifenacin Alone for Overactive Bladder in FemalesCompletedNCT07312955Not applicable1 country
- NOCDURNA PASS Study Using Registries in Denmark, Germany and SwedenCompletedNCT047406453 countries
- TEST-ON - Does iStim Reduce Urinary Urgency?CompletedNCT04957524Not applicable1 country
- Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal WomenCompletedNCT06508944Phase 41 country
- A Study to Find Out if Daridorexant is Safe and Efficacious in Patients With Insomnia and Comorbid NocturiaCompletedNCT05597020Phase 43 countries
- Sleep, Hypertension, and Nocturia: a Multicomponent Approach for Comorbid IllnessesCompletedNCT05419830Not applicable1 country
- A Multinational Study Comparing the Long-term Efficacy and Safety of Two Medicines, Solifenacin Succinate and Mirabegron Taken Together, or Separately, in Subjects With Symptoms of Overactive BladderCompletedNCT02045862Phase 332 countries
- This Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and Mirabegron Taken Together, or Separately, or a Mock Treatment (Placebo) in Subjects With Symptoms of Overactive BladderCompletedNCT01972841Phase 342 countries
- Pathophysiologic Study to Understand and Possibly Treat NocturiaWithdrawnNCT05298384Not applicable1 country
- Behavioral or Solifenacin Therapy for Urinary Symptoms in Parkinson DiseaseCompletedNCT03149809Phase 31 country
- TUCSON Study: Tackling Underlying Causes of Sleep Related Nocturia NocturiaCompletedNCT054048281 country
- Effect of Tibial Transcutaneous Electrostimulation in Women with Urgency Urinary IncontinenceCompletedNCT05590481Not applicable1 country
- Food and Salt Handling in DiuresisCompletedNCT04526340Not applicable1 country
- MRI Guided Transrectal Prostate Laser Ablation for Benign Prostatic Hypertrophy (BPH)CompletedNCT03131544Not applicable1 country
- Bladder Diary for Female Storage LUTSCompletedNCT062225151 country
- Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)CompletedNCT05368246Not applicable1 country
- Acupuncture Combined With Mirabegron in the Treatment of OABActive, not recruitingNCT06181019Phase 11 country
- Discovering the Effect of Venous Insufficiency on NocturiaCompletedNCT04266496Not applicable1 country
- Abdominal Muscle Exercises on Nocturia and Sleep Quality in Women With Type 2 DiabetesCompletedNCT05222477Not applicable1 country
- Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in AdultsCompletedNCT05464589Not applicable1 country
- Enhancing Behavioral Treatment for Women With Pelvic Floor DisordersCompletedNCT03623880Not applicable1 country