Muscle Hypertonia clinical trials
The registry lists 46 studies for Muscle Hypertonia across more than 10 countries. 6 are recruiting or about to start. 12 of them are mainly about Muscle Hypertonia (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-14. Counting its 2 narrower conditions too, such as Muscle Spasticity: 674 studies, 137 open.
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Who runs them
University of Southern California (4) · Chang Gung University (3) · Vanderbilt University Medical Center (3) · BTL Industries Ltd. (3) · Charles University, Czech Republic (2) · Pomeranian Medical University Szczecin (2) · Fatih Sultan Mehmet Training and Research Hospital (1) · University of North Carolina, Chapel Hill (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Electrical Neuromodulation for Modifying Spinal Network Involved in Spasticity · University of Mississippi Medical Center
- May 2027Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia · University of Michigan
- Aug 2027A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management · HillMed Inc.
Who these studies take
Of the 3 Muscle Hypertonia studies recruiting now, 1 (33%) set no upper age limit and 2 (67%) stop at 75 or younger. 3 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (100%) | 3 (100%) |
| 18 | 3 (100%) | 3 (100%) |
| 30 | 1 (33%) | 1 (33%) |
| 40 | 1 (33%) | 1 (33%) |
| 50 | 1 (33%) | 1 (33%) |
| 65 | 1 (33%) | 1 (33%) |
| 75 | 1 (33%) | 1 (33%) |
| 85 | 1 (33%) | 1 (33%) |
Across all 46 studies, recruiting or not: 52% stop at 75 or younger and 46% at 65; 30% take children; 11% are for women only and 2% for men only; 50% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 46 of 46. search them.
- Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in HypotoniaRecruitingNCT05527652Not applicable1 country
- Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke PatientsNot yet recruitingNCT074293831 country
- Turkish Translation , Validity and Reliability of the Hypertonia Assessment Tool in Children With Motor DisordersRecruitingNCT072674421 country
- Longitudinal Study of Neurogenetic DisordersRecruitingNCT034920601 country
- A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain ManagementNot yet recruitingNCT05062902Early Phase 11 country
- Efficacy of Shock Wave Therapy in Post-Stroke Muscle Spasticity ManagementNot yet recruitingNCT06815328Not applicable1 country
- Effects of Dry Needling on Electromyographic Activity and Ultrasonographic Characteristics in Post-Stroke SpasticityCompletedNCT06017960Not applicable1 country
- Electrical Neuromodulation for Modifying Spinal Network Involved in SpasticityActive, not recruitingNCT07792616Not applicable1 country
- Single and Multiple Ascending Dose Study of MTR-601 in Healthy IndividualsCompletedNCT06117020Phase 11 country
- Validation of a Spasticity Measurement ToolActive, not recruitingNCT053741741 country
- Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.Active, not recruitingNCT05256771Not applicable1 country
- Surface EMG Biofeedback for Children With Cerebral PalsyWithdrawnNCT01681888Not applicable1 country
- Impact of Listening to Low Tones on Motor Function in Children With CPCompletedNCT00394641Not applicable1 country
- Antagonist Activation Measurement at the Ankle Using High-density and Bipolar Surface EMG in Chronic HemiparesisCompletedNCT06099132
- Reactibility of Muscle Volume to Ribs Mobilization According to MojžíšováCompletedNCT046857851 country
- Load During Sweep Rowing and the Influence on the PostureCompletedNCT056855631 country
- Effectiveness of Physiotherapy Treatments in Temporomandibular Joint DysfunctionStatus unknownNCT05619380Not applicable1 country
- The Relation of Ankle Mobility and Achilles Tendon, Plantar Fascia and Iliotibial Band Mechanical PropertiesCompletedNCT04737226Not applicable1 country
- Effect of Local Pressure on Muscle Activity and General Relaxation in Persons With Hypertonia Following StrokeWithdrawnNCT04188769Not applicable1 country
- The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.Status unknownNCT05021874Not applicable1 country
- Quantitative Evaluation of Muscle Tone Using Elastic UltrasoundStatus unknownNCT042754011 country
- HIFEM for Arms, Lower Limbs, and Oblique MusclesCompletedNCT04426526Not applicable1 country
- Efficacy of Dry Needling in the Spasticity Post-strokeStatus unknownNCT04435561Not applicable
- High-Intensity Focused Electromagnetic (HIFEM) Field Device in Women After ChildbirthCompletedNCT03758690Not applicable1 country
- MRI Evaluation of Change in Gluteal Muscles Following the Treatment With HIFEM DeviceCompletedNCT03815747Not applicable1 country
- Grand Autohemo-Therapy With Oxygen-ozone on Patients With HypertoniaTerminatedNCT019026021 country
- Evaluation and Comparison of Women Pelvic Floor With and Without Sexual Dysfunction (Vaginismus)CompletedNCT03176069Not applicable1 country
- Optimal Interstimulus Interval For Consecutive H-Reflex Responses In Patients With SpasticityCompletedNCT04005937Not applicable1 country
- Cranial Laser Reflex Technique for Hamstring FunctionCompletedNCT03044106Not applicable1 country
- Multichannel tDCS to Reduce Hypertonia in Patients With Prolonged DOCCompletedNCT03797573Phase 11 country
- Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care FacilityCompletedNCT032509881 country
- Using Telemedicine to Improve Spasticity Diagnosis RatesCompletedNCT032113901 country
- Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for SpasticityCompletedNCT032099601 country
- Hypertonia in Patients With Cerebral PalsyCompletedNCT001237081 country
- Evaluation of the Effect of the Presence Of Clowns on Pain and Anxiety Seen During Injections Botulinum Toxin in ChildCompletedNCT031492631 country
- Assessment of the Efficacy of a Sensorimotor Approach After Maximum Three Sessions in Subjects With TMD With HypertoniaStatus unknownNCT02632643Not applicable3 countries
- Effects of Long-term Foam Rolling Compared to Static Stretching on Hamstring Muscle FlexibilityStatus unknownNCT02808923Not applicable
- ASIS for Botox in Upper Limb SpasticityStatus unknownNCT02074150Phase 1/21 country
- Use of Surface Electromyography Biofeedback to Improve Reaching in Children With Cerebral PalsyCompletedNCT004731611 country
- Use of EMG to Assess Clinical HypertoniaCompletedNCT004729141 country
- Effects of Continuous Passive Motion on the Spinal Circuitries and Its Adaptation in Patients With Spasticity Resulting From Upper Motor Neuron LesionsCompletedNCT02122276Not applicable1 country
- The Effects of Continuous Passive Motion on Hypertonia of Soleus in Individuals With Cerebral PalsyCompletedNCT02003755Not applicable1 country
- The Effect of Continuous Passive Motion Training on Neuromuscular AdaptationCompletedNCT01988142Not applicable1 country
- Quantification of Upper Extremity HypertoniaCompletedNCT002858701 country
- Exploring Hypertonia in Children With Cerebral PalsyStatus unknownNCT017441581 country
- Intrathecal Baclofen Therapy and Paroxysmal Dysautonomia in Severe Brain-Injured PatientsTerminatedNCT00221689Phase 21 country