Muscle Rigidity clinical trials
The registry lists 31 studies for Muscle Rigidity across more than 10 countries. 9 are recruiting or about to start. 4 of them are mainly about Muscle Rigidity (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-05.
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Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (4) · University Ghent (2) · Medical University of Vienna (1) · The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School (1) · Regeneron Pharmaceuticals (1) · University Medical Center Groningen (1) · Neuromed IRCCS (1) · Universidade Federal do Rio Grande do Norte (1)
What is being tested here
Drugs under test in Muscle Rigidity studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Botulinum Toxins | 0 | 0 | 1 |
| Immunoglobulins, Intravenous | 0 | 0 | 1 |
| Immunoglobulin G | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Dec 2026Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD · Mustafa Kemal University
Who these studies take
Of the 6 Muscle Rigidity studies recruiting now, 2 (33%) set no upper age limit and 1 (17%) stop at 75 or younger. 1 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (17%) | 1 (17%) |
| 18 | 2 (33%) | 2 (33%) |
| 30 | 4 (67%) | 4 (67%) |
| 40 | 5 (83%) | 5 (83%) |
| 50 | 6 (100%) | 6 (100%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 2 (33%) | 2 (33%) |
Across all 31 studies, recruiting or not: 29% stop at 75 or younger and 19% at 65; 23% take children; 0% are for women only and 6% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 31 of 31. search them.
- Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMDRecruitingNCT078506741 country
- First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)RecruitingNCT07216066Phase 12 countries
- Validity and Reliability of the Hypertonia Assessment Tool (HAT) in Stroke PatientsNot yet recruitingNCT074293831 country
- Virtual tES Device Treatment for Parkinson's Disease Motor SymptomsRecruitingNCT07182058Phase 1/21 country
- Acupuncture and Moxibustion for Motor Symptoms in Early Parkinson's DiseaseRecruitingNCT06874803Not applicable1 country
- Blood Flow Technique Effect on the Muscle MechanicsNot yet recruitingNCT06861699
- Differential Assessment of HypertoniaRecruitingNCT06596187Not applicable1 country
- Neurophysiological Evaluation of Muscle ToneRecruitingNCT050707801 country
- Surface EMG to Measure Paratonia in DementiaNot yet recruitingNCT05606445
- A Multifactorial Exercise Program to Reduce Falls in People With Parkinson DiseaseCompletedNCT02302144Not applicable1 country
- Fine and Gross Motor Function and Relationship With Muscle Tone in Older Adults With and Without DementiaCompletedNCT03479567Not applicable1 country
- Comparison of Different Feeding Appliances for Cleft Palate BabiesCompletedNCT06103162Not applicable1 country
- Investigation on a Topical Cosmetic Pain Lotion (Egyfil) for Stiffness and Pain ReliefCompletedNCT05711953Not applicable1 country
- Short-term Effect of Positioning Cushions and Harmonic Techniques on Paratonia in Persons With DementiaCompletedNCT03538405Not applicable1 country
- Effects of Whole Body Vibration in Parkinson's Disease SymptomsStatus unknownNCT05621031Not applicable1 country
- Effects of a Dynamic Upper Limb Orthosis in Patients With Parkinson's DiseaseStatus unknownNCT04815382Not applicable1 country
- Physiotherapeutic Case Studies in Frozen Shoulder PathologyCompletedNCT05175586Not applicable1 country
- Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact LensCompletedNCT03971227Not applicable1 country
- Joint Preserving Surgery for Correction of Spasmodic Flat- Foot in Skeletally Mature FootStatus unknownNCT03880318Not applicable
- Long-term Surveillance of the MedStream Programmable Infusion SystemTerminatedNCT017120871 country
- Modified Exercise Programme in Individuals With Parkinson's DiseaseCompletedNCT03473834Not applicable1 country
- A Study of Movement Disorders Using the QMAT At-Home Testing DeviceTerminatedNCT019058391 country
- Measures of Motor Impairment in Early Parkinson's DiseaseCompletedNCT002912651 country
- Differents Intensities of Passive Stretching on ROM, Neuromuscular and Performance in Soccer Players: A Blinded RCTStatus unknownNCT03150563Not applicable1 country
- the Diagnostic Value of Rigiscan Test (Nocturnal Penile Tumescence and Rigidity, NPTR) in Chinese MalesStatus unknownNCT025738051 country
- Association Between Laser Interferometric Measurement of Fundus Pulsation and Pneumotonometric Measurement of Pulsatile Ocular Blood Flow in Patients With Age-related Macular DegenerationCompletedNCT00991666Not applicable1 country
- Safety and Effectiveness of Botulinum Toxin in Elderly Patients With Dementia and Muscle StiffnessCompletedNCT02212119Phase 21 country
- Use of EMG to Assess Clinical HypertoniaCompletedNCT004729141 country
- Effects of Deep Brain Stimulation on Motor, Mood, and Cognitive Symptoms in Parkinson's DiseaseCompletedNCT00360009Not applicable1 country
- Classification of Cerebral Palsy SubtypesCompletedNCT000728001 country
- Intravenous Immunoglobulin (IVIg) for the Treatment of Stiff-Man Syndrome (SMS)CompletedNCT00001550Phase 11 country