Multiple Sclerosis: all 3,524 studies

Page 8 of 36. Open to participants first (668), then studies with results posted, then the rest; newest registration first within each.

• Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MSCompletedNCT04942938Not applicableResults posted
• Prospective Effectiveness and Safety Study of Cladribine in Participants Who Change First-line DMD Treatments for Multiple Sclerosis (CLAD CROSS)CompletedNCT04934800Results posted
• Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple SclerosisTerminatedNCT04925557Phase 2/3Results posted
• The Therapeutic Effects of Forced Aerobic Exercise in Multiple SclerosisCompletedNCT04906057Not applicableResults posted
• Proof-of-concept Study for SAR441344 (Frexalimab) in Relapsing Multiple SclerosisActive, not recruitingNCT04879628Phase 2Results posted
• A Open-label Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With OfatumumabTerminatedNCT04878211Phase 4Results posted
• Ocrelizumab for Preventing Clinical Multiple Sclerosis in Individuals With Radiologically Isolated Disease.TerminatedNCT04877457Phase 4Results posted
• Exploring the Immune Response to SARS-CoV-2 COVID-19 Vaccines in Patients With Relapsing Multiple Sclerosis (RMS) Treated With OfatumumabCompletedNCT04869358Phase 4Results posted
• Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb SpasticityTerminatedNCT04815967Phase 2/3Results posted
• Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC)CompletedNCT04792567Phase 4Results posted
• Extension to the MAGNIFY MS Trial on Mavenclad® (Magnify MS Extension)CompletedNCT04783935Phase 4Results posted
• Cognition and HRQoL in Adults With Highly-active RMS in Year 3 and 4 After Initial Mavenclad® Dose (CLARIFY MS Extension)CompletedNCT04776213Phase 4Results posted
• Addition of Belimumab to B-cell Depletion in Relapsing-remitting Multiple SclerosisTerminatedNCT04767698Phase 2Results posted
• Discontinuation of Disease Modifying Therapies (DMTs) in Multiple Sclerosis (MS): Extension of the DISCOMS StudyCompletedNCT04754542Results posted
• Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple SclerosisActive, not recruitingNCT04742400Phase 2Results posted
• A Multicenter Study to Assess Response to Influenza Vaccine in Multiple Sclerosis Participants Treated With OfatumumabCompletedNCT04667117Phase 4Results posted
• Trial to Evaluate the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple SclerosisCompletedNCT04657666Phase 3Results posted
• Low Load Resistance Training Using Blood Flow Restriction for People With Multiple SclerosisCompletedNCT04633759Not applicableResults posted
• Assessment of ANK-700 in Patients With Relapsing Remitting Multiple SclerosisCompletedNCT04602390Phase 1Results posted
• HFS (High-Fiber Supplement) in MS (Multiple Sclerosis)CompletedNCT04574024Phase 1/2Results posted
• Comparative Bioavailability of BAFIERTAM™ (Monomethyl Fumarate) and Tecfidera® (Dimethyl Fumarate) in Healthy SubjectsCompletedNCT04570670Phase 1Results posted
• A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis (PPMS)Active, not recruitingNCT04548999Phase 3Results posted
• A Study to Evaluate the Efficacy, Safety and Pharmacokinetics (PK) of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)Active, not recruitingNCT04544436Phase 3Results posted
• Aerobic Exercise for Remyelination in Multiple SclerosisCompletedNCT04539002Not applicableResults posted
• Clinical Trial Assessing Temelimab Following Rituximab Treatment in Patients With Relapsing Forms of Multiple SclerosisCompletedNCT04480307Phase 2Results posted
• Non-invasive Transcranial Electrical Stimulation in MSCompletedNCT04466228Not applicableResults posted
• Cerebellar tDCS and Balance Training in PwMSCompletedNCT04391023Not applicableResults posted
• Time Restricted Eating Outcomes in Multiple SclerosisCompletedNCT04389970Not applicableResults posted
• Neuroproprioceptive "Facilitation, Inhibition" and Brain PlasticityCompletedNCT04355663Not applicableResults posted
• An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to OfatumumabCompletedNCT04353492Phase 3Results posted
• Study of Evobrutinib in Participants With RMS (evolutionRMS 2)TerminatedNCT04338061Phase 3Results posted
• Study of Evobrutinib in Participants With RMS (evolutionRMS 1)TerminatedNCT04338022Phase 3Results posted
• MitoQ for Fatigue in Multiple Sclerosis (MS)CompletedNCT04267926Phase 1/2Results posted
• Effects of Ocrelizumab on B-cell Tolerance Defect in Relapsing Multiple SclerosisCompletedNCT04261790Phase 4Results posted
• Telehealth Pain Self-Management for Employed AdultsCompletedNCT04248725Not applicableResults posted
• Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia ActivationCompletedNCT04230174Phase 4Results posted
• Validity and Reliability of the 6-minute Walk Test Over a Distance of 6 Metres in People With Multiple SclerosisCompletedNCT04228328Results posted
• Safety and Effectiveness of Nabiximols Oromucosal Spray as Add-on Therapy in Participants With Spasticity Due to Multiple SclerosisTerminatedNCT04203498Phase 3Results posted
• Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to OcrelizumabCompletedNCT04175834Phase 3Results posted
• Role of Microglial Activation and Norepinephrine Transporter Abnormalities in Pathogenesis of MS-related FatigueCompletedNCT04144257Phase 1/2Results posted
• Advancing Understanding of Transportation OptionsCompletedNCT04141891Not applicableResults posted
• A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMSCompletedNCT04121221Phase 3Results posted
• Efficacy and Safety of the Biosimilar Natalizumab PB006 in Comparison to Tysabri®CompletedNCT04115488Phase 3Results posted
• A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple SclerosisActive, not recruitingNCT04075266Phase 2Results posted
• Study of Evobrutinib in Participants With RMSTerminatedNCT04032171Phase 3Results posted
• Study of Evobrutinib in Participants With Relapsing Multiple Sclerosis (RMS)TerminatedNCT04032158Phase 3Results posted
• Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisCompletedNCT04025554Phase 1/2Results posted
• tDCS and Glucose Uptake in Leg MusclesCompletedNCT04016844Not applicableResults posted
• Pilot Study of Powered Exoskeleton Use for Gait Rehabilitation in Individuals With Multiple SclerosisCompletedNCT04000373Not applicableResults posted
• G-EO Gait Rehabilitation Training in Progressive Multiple SclerosisCompletedNCT03980145Not applicableResults posted
• Cladribine Tablets: Collaborative Study to Evaluate Impact On Central Nervous System Biomarkers in Multiple SclerosisCompletedNCT03963375Phase 4Results posted
• Long-Term Outcomes and Durability of Effect Following Treatment With Cladribine Tablets for MS (CLASSIC-MS)CompletedNCT03961204Phase 4Results posted
• A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)CompletedNCT03933215Results posted
• A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)CompletedNCT03933202Results posted
• Impact of Physical Activity on Cognitive Outcomes in Youth With Pediatric-Onset Multiple Sclerosis (POMS)TerminatedNCT03933020Not applicableResults posted
• Simvastatin in Secondary Progressive Multiple SclerosisCompletedNCT03896217Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric ParticipantsTerminatedNCT03870763Phase 3Results posted
• tDCS to Lower Neuropathic Pain and Fatigue in People With Multiple SclerosisCompletedNCT03870048Not applicableResults posted
• Short-term B-cell Depletion in Relapsing Multiple SclerosisCompletedNCT03853746Phase 4Results posted
• MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS)Active, not recruitingNCT03846219Phase 2Results posted
• Aspirin for Exercise in Multiple Sclerosis (ASPIRE)CompletedNCT03824938Phase 3Results posted
• Activity and Balanced Eating to Reduce Comorbidities and Symptoms of MSTerminatedNCT03808545Not applicableResults posted
• Comparison of Robot-Assisted Gait Training and Conventional Therapy in Multiple Sclerosis PatientsCompletedNCT03801473Not applicableResults posted
• Safety and Efficacy of Repeated Administration of NurOwn (MSC-NTF Cells) in Participants With Progressive MSCompletedNCT03799718Phase 2Results posted
• Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving LemtradaCompletedNCT03784898Phase 4Results posted
• Isokinetic Exercises in Patients With Multiple SclerosisCompletedNCT03779724Not applicableResults posted
• Vaginal Estriol in Multiple SclerosisCompletedNCT03774407Phase 2/3Results posted
• Transcranial Direct Current Stimulation and Walking in Multiple SclerosisCompletedNCT03757819Not applicableResults posted
• Safety and Tolerability of ISX (Isoxsuprine HCL) in MS RelapsesCompletedNCT03752307Phase 1/2Results posted
• Effects of Cladribine Tablets on the PK of Microgynon®CompletedNCT03745144Phase 1Results posted
• A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Relapsing Forms of Multiple SclerosisCompletedNCT03737851Phase 2Results posted
• A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple SclerosisCompletedNCT03737812Phase 2Results posted
• A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab AdministrationCompletedNCT03689972Phase 3Results posted
• Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: Project EXACTCompletedNCT03677440Not applicableResults posted
• LSFG-SKIN, Laser Speckle FlowgraphyTerminatedNCT03660618Not applicableResults posted
• Combined Effect of Transcranial Direct Current Stimulation (tDCS) and Physical Activity on Gait and Functional Mobility in Participants With Multiple SclerosisCompletedNCT03658668Not applicableResults posted
• A Positive Psychology Intervention for Patients With Multiple SclerosisCompletedNCT03637699Not applicableResults posted
• Safety and Tolerability of Conversion From Oral, Injectable, or Infusion Disease Modifying Therapies to Dose-titrated Oral Siponimod (Mayzent) in Advancing RMS PatientsCompletedNCT03623243Phase 3Results posted
• Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis FatigueCompletedNCT03621761Phase 4Results posted
• Virtual Reality (VR) to Improve Quality of Life in Patients Diagnosed With Neurological DisordersCompletedNCT03606668Not applicableResults posted
• A Study to Evaluate the Safety of Administering Ocrelizumab Per a Shorter Infusion Protocol in Participants With Primary Progressive Multiple Sclerosis (PPMS) and Relapsing Multiple Sclerosis (RMS)CompletedNCT03606460Phase 3Results posted
• This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)CompletedNCT03599245Phase 3Results posted
• Fecal Microbiota Transplantation (FMT) of FMP30 in Relapsing-Remitting Multiple SclerosisTerminatedNCT03594487Phase 1Results posted
• Brain Targets in Patients With Bladder Emptying DifficultiesCompletedNCT03574610Not applicableResults posted
• Digital Cognition in Multiple SclerosisCompletedNCT03569618Not applicableResults posted
• Impact of Custom Assistive and Adaptive Technology in RehabilitationCompletedNCT03567239Not applicableResults posted
• A Safety and Efficacy Study of ADS-5102 in Patients With Multiple Sclerosis and Walking ImpairmentCompletedNCT03567057Phase 3Results posted
• Assessment of tDCS-Induced Neuronal Responses in Multiple Sclerosis (MS) With Advanced MRICompletedNCT03564496Not applicableResults posted
• Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With OcrevusCompletedNCT03562975Results posted
• A 12 Week Randomized Open Label Parallel Group Multicenter Study to Evaluate Bioequivalence of 20 mg Subcutaneous Ofatumumab Injected by Pre-filled Syringe or Autoinjector in Adult RMS PatientsCompletedNCT03560739Phase 2Results posted
• Protective Stepping in People With MSCompletedNCT03551665Not applicableResults posted
• Fatigue Management Programs for People With MSCompletedNCT03550170Not applicableResults posted
• Ketamine for Treatment of MS FatigueCompletedNCT03500289Phase 1/2Results posted
• A Pilot Trial of Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) to Enhance Motor Learning in Progressive Multiple Sclerosis (MS)CompletedNCT03499314Not applicableResults posted
• Melatonin in Patients With Multiple Sclerosis (MS).CompletedNCT03498131Early Phase 1Results posted
• Comparative Effectiveness Study Telerehab Versus ConventionalCompletedNCT03468868Not applicableResults posted
• Safety and Efficacy of ADS-5102 in Multiple Sclerosis Patients With Walking ImpairmentCompletedNCT03436199Phase 3Results posted
• A Trial of Bile Acid Supplementation in Patients With Multiple SclerosisCompletedNCT03423121Phase 1/2Results posted
• Carnosine Loading and Periodized Training in MS and HCCompletedNCT03418376Not applicableResults posted
• Muscle Vibration in MS to Improve WalkingTerminatedNCT03403413Not applicableResults posted

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