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RecruitingNCT07193823MSUpdated Sep 26, 2025

Sexual Dysfunction in Women With Multiple Sclerosis (MS)

An observational study in Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting and Fatigue in Multiple Sclerosis, sponsored by Ege University. Recruiting at 1 site in Turkey (Türkiye). Open to female participants aged 25 Years to 50 Years. Per ClinicalTrials.gov, last updated 2025-09-26.

Sponsored by Ege University · Observational

From the registry’s dates

  • Primary completion was expected by Oct 2025, 1 year 1 month ago, but the record still lists the study as recruiting.
  • Started Jul 2024; still recruiting 2 years 3 months later.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
140
Ages
25 Years to 50 Years
Sex
Female
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Study summary

Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with MS. The secondary objective is to evaluate the relationship between sexual dysfunction and fatigue, depression, anxiety, overactive bladder symptoms, and cognitive dysfunction.

For this purpose, the following validated instruments will be used: the Female Sexual Function Index (FSFI) to assess sexual dysfunction, the Brief International Cognitive Assessment for MS (BICAMS) to evaluate cognitive function, the Hospital Anxiety and Depression Scale (HADS) to assess depression and anxiety, the Fatigue Severity Scale (FSS) to measure fatigue, and the Overactive Bladder Questionnaire (OAB-V8) to evaluate overactive bladder symptoms.

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Conditions studied

  • Multiple Sclerosis
  • Multiple Sclerosis (MS) - Relapsing-remitting
  • Fatigue in Multiple Sclerosis
  • Sexual Disfunction
  • Cognitive Dysfunction
  • Depression
  • Anxiety
  • Overactive Bladder
  • Fatigue

Keywords

  • multiple sclerosis
  • sexual dysfunction
  • cognitive dysfunction
  • depression
  • anxiety
  • overactive bladder
  • fatigue
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In context

Multiple Sclerosis

3,264 studies on the registry are indexed under Multiple Sclerosis; 659 are open to participants now.

This study's planned enrollment of 140 is above the median of 100 across 970 observational studies indexed under Multiple Sclerosis.

Browse Multiple Sclerosis studies →

Lead sponsor

Ege University is the lead sponsor of 377 studies on the registry; 48 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
25 Years to 50 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Female patients with MS under follow-up at the Department of Neurology, Ege University.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Female patients aged 25-50 years
  • Literate and able to comprehend written and spoken instructions
  • Diagnosed with relapsing-remitting form of multiple sclerosis
  • Having a continuous/regular sexual partner
  • Expanded Disability Status Scale (EDSS) score ≤ 5
  • At least 3 months since the last relapse
  • Sexually active within the past 3 months
  • Spasticity level \< grade 2 according to the Modified Ashworth Scale

Exclusion criteria

Exclusion Criteria:

  • Pregnancy
  • Illiteracy or inability to understand spoken or written instructions
  • Absence of a continuous/regular sexual partner
  • Expanded Disability Status Scale (EDSS) score > 5
  • Not sexually active within the past 3 months
  • Spasticity level ≥ grade 2 according to the Modified Ashworth Scale
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Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
140 participants (estimated)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Prevalence of sexual dysfunction in female patients with multiple sclerosis

    Time frame: At enrollment (Baseline, cross-sectional assessment)

Secondary outcomes

  1. Association between sexual dysfunction and cognitive dysfunction, fatigue, depression, anxiety, and overactive bladder symptoms

    Time frame: At enrollment (Baseline, cross-sectional assessment)

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Study locations

1 of 1 sites recruiting
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References and documents

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 26, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07193823
Lead sponsor
Ege University
Responsible party
Merve Dokumaci (Resident Doctor, Department of Physical Medicine and Rehabilitation, Ege University) — Principal investigator
First posted
Sep 26, 2025
Start date
Jul 16, 2024
Primary completion
Oct 2025 (estimated)
Completion
Nov 2025 (estimated)
Last update
Sep 26, 2025

Study contacts

Merve Dokumaci, Resident doctor
Contact
dokumacimerve@gmail.com
+905435088428
Yesim Akkoc, M.D., Prof
study director · Ege University Faculty of Medicine, Department of Physical Medicine and Rehabilitation
View the source record on ClinicalTrials.gov ↗

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