Meconium Aspiration Syndrome clinical trials
The registry lists 25 studies for Meconium Aspiration Syndrome across more than 10 countries. 2 are recruiting or about to start. 15 of them are mainly about Meconium Aspiration Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
Lady Hardinge Medical College (4) · NICHD Neonatal Research Network (3) · The Hospital for Sick Children (1) · St. Louis University (1) · University of Alabama at Birmingham (1) · Sir Takhtasinhji General Hospital (1) · University Hospital Padova (1) · Benha University (1)
What is being tested here
Drugs under test in Meconium Aspiration Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Caffeine citrate | 1 | 0 | 1 |
| Caffeine | 1 | 0 | 1 |
| Nitric Oxide | 0 | 2 | 2 |
| Budesonide | 0 | 1 | 1 |
| Sildenafil | 0 | 0 | 1 |
| Poractant alfa | 0 | 0 | 1 |
| Lucinactant | 0 | 1 | 1 |
| Alprostadil | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Aug 2027CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO) · University of Alberta
Who these studies take
Of the 1 Meconium Aspiration Syndrome studies recruiting now, 0 (0%) set no upper age limit and 1 (100%) stop at 75 or younger. 1 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (100%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 0 (0%) | 0 (0%) |
| 30 | 0 (0%) | 0 (0%) |
| 40 | 0 (0%) | 0 (0%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 25 studies, recruiting or not: 88% stop at 75 or younger and 88% at 65; 96% take children; 8% are for women only and 0% for men only; 24% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 25 of 25. search them.
- CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)Not yet recruitingNCT06972108Phase 2
- Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU SettingRecruitingNCT073447141 country
- Pulmonary Function Using Non-invasive Forced OscillometryActive, not recruitingNCT03346343Not applicable1 country
- Efficacy of Nebulised Inhalational Steroids in Neonates With Meconium Aspiration SyndromeCompletedNCT07763119Phase 31 country
- Interleukin-6 in the Development of Meconium Aspiration Syndrome in NewbornCompletedNCT07394322Not applicable1 country
- Early Bolus Surfactant Replacement Therapy Versus Standard Care in Term Neonates With Meconium Aspiration SyndromeCompletedNCT06090981Not applicable1 country
- Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in NewbornsCompletedNCT01757782Phase 41 country
- Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing AbnormalitiesWithdrawnNCT03996317Not applicable1 country
- Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMOCompletedNCT003712411 country
- Time of Positive Pressure Ventilation in Non-vigorous Infants Born Through Meconium-stained Amniotic FluidCompletedNCT04076189Not applicable1 country
- Helium Oxygen Mixture in the Treatment of Meconium Aspiration SyndromeCompletedNCT02620891Not applicable1 country
- Meconium Aspiration and Tracheal Suctioning-Feasibility StudyWithdrawnNCT02708563Not applicable
- Inhaled PGE1 in Neonatal Hypoxemic Respiratory FailureWithdrawnNCT00598429Phase 21 country
- Early Inhaled Nitric Oxide for Respiratory Failure in NewbornsTerminatedNCT00005773Phase 31 country
- Inhaled Nitric Oxide Study for Respiratory Failure in NewbornsTerminatedNCT00005776Phase 32 countries
- Efficacy and Safety of Gastric Suctioning During Neonatal ResuscitationTerminatedNCT00729989Not applicable1 country
- Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration SyndromeCompletedNCT02041546Phase 41 country
- High Flow Ventilation With Volume GuaranteeStatus unknownNCT02571231Not applicable
- Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration SyndromeCompletedNCT01328483Not applicable1 country
- Comparison Of Surfactant Lung Lavage With Standard Care In The Treatment Of Meconium Aspiration SyndromeCompletedNCT01310621Not applicable1 country
- Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained BabiesCompletedNCT01758822Not applicable1 country
- Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration SyndromeTerminatedNCT00004500Phase 31 country
- Post Term Pregnancy - Induction of Labor or Monitoring of PregnancyCompletedNCT00385229Not applicable1 country
- Use of Heliox in the Management of Neonates With Meconium Aspiration SyndromeCompletedNCT01274845Not applicable1 country
- Surfactant Lavage vs. Bolus Surfactant in Neonates With Meconium AspirationStatus unknownNCT00312507Phase 31 country