Malabsorption Syndromes clinical trials
The registry lists 54 studies for Malabsorption Syndromes across more than 10 countries. 12 are recruiting or about to start. 14 of them are mainly about Malabsorption Syndromes (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-29. Counting its 6 narrower conditions too, such as Celiac Disease: 666 studies, 126 open.
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Status
Who runs them
Boston Children's Hospital (4) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Elgan Pharma Ltd. (3) · University of Kansas Medical Center (2) · Hvidovre University Hospital (2) · ImmusanT, Inc. (2) · Dr. Schär AG / SPA (2) · Zealand Pharma (2)
What is being tested here
Drugs under test in Malabsorption Syndromes studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Glepaglutide | 1 | 2 | 2 |
| Glutens | 1 | 0 | 1 |
| Nexvax2 | 0 | 0 | 2 |
| Amino Acids | 0 | 0 | 1 |
| Ustekinumab | 0 | 0 | 1 |
| SMOFlipid | 0 | 0 | 1 |
| Apilimod | 0 | 0 | 1 |
| Human Growth Hormone | 0 | 0 | 1 |
| Colesevelam | 0 | 0 | 1 |
| Lidocaine | 0 | 1 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6, phase 3 first
- Nov 2027Efficacy and Safety of ELGN-2112 on Intestinal Malabsorption in Preterm Infants · Phase 3 · Elgan Pharma Ltd.
- Dec 2026Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction · Romanian Society for Enteral and Parenteral Nutrition
- Feb 2027Elemental 028 Extra Case Studies · Nutricia UK Ltd
- Mar 2027Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC) · Napo Therapeutics, S.p.A.
- Jun 2027Assess the Safety of ELGN-2112 in Preterm Infants Born Under 26 Weeks GA and IUGR Infants Born 26-32 Weeks GA · Elgan Pharma Ltd.
- Jun 2027A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB · Boston Children's Hospital
Who these studies take
Of the 8 Malabsorption Syndromes studies recruiting now, 4 (50%) set no upper age limit and 3 (38%) stop at 75 or younger. 5 (63%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (38%) | 3 (38%) |
| 18 | 6 (75%) | 6 (75%) |
| 30 | 5 (63%) | 5 (63%) |
| 40 | 5 (63%) | 5 (63%) |
| 50 | 5 (63%) | 5 (63%) |
| 65 | 5 (63%) | 5 (63%) |
| 75 | 5 (63%) | 5 (63%) |
| 85 | 5 (63%) | 5 (63%) |
Across all 54 studies, recruiting or not: 52% stop at 75 or younger and 35% at 65; 37% take children; 0% are for women only and 0% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Malabsorption Syndromes studies take
Of 16 interventional studies with no phase under Malabsorption Syndromes, half reached primary completion within 18 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 18 mo12–65 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 54. Browse all 54 → or search them.
- Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBSRecruitingNCT07197944Phase 314 countries
- Immune Responses to GlutenEnrolling by invitationNCT05209568Not applicable1 country
- A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORBRecruitingNCT03530852Not applicable1 country
- A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORBEnrolling by invitationNCT056357471 country
- Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)RecruitingNCT06904872Phase 22 countries
- Assess the Safety of ELGN-2112 in Preterm Infants Born Under 26 Weeks GA and IUGR Infants Born 26-32 Weeks GARecruitingNCT05904626Phase 21 country
- Elemental 028 Extra Case StudiesRecruitingNCT06877923Not applicable1 country
- Long-term Health Outcomes of Screen Detected and Potential Celiac Disease PatientsNot yet recruitingNCT073661511 country
- Efficacy and Safety of ELGN-2112 on Intestinal Malabsorption in Preterm InfantsRecruitingNCT05670951Phase 31 country
- Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal DysfunctionRecruitingNCT06510348Not applicable1 country
- Understanding Gut Symptoms in People With Cystic FibrosisRecruitingNCT059346561 country
- Sucrase-isomaltase Deficiency as a Cause of Irritable Bowel SyndromeNot yet recruitingNCT05159115Not applicable
- Efficacy and Safety Evaluation of Glepaglutide in Treatment of Short Bowel SyndromeActive, not recruitingNCT07228403Phase 37 countries
- Impact of Different Carbohydrate Feedings on a Hydrogen Breath Curve and Self-reported Gastrointestinal ComplaintsCompletedNCT06648967Not applicable1 country
- Study to Assess the Efficacy and Safety of NTRA-2112 on Intestinal Malabsorption in Preterm InfantsTerminatedNCT02510560Phase 310 countries
- IMPact of AerobiC Exercise in Addition to Nutritional Treatment on Quality of Life After PancreatectomyActive, not recruitingNCT06858631Not applicable1 country
- High Energy High Protein Peptide Feed StudyCompletedNCT03140371Not applicable1 country
- Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM)CompletedNCT05130047Phase 21 country
- Fat Absorption and Metabolism After Roux-en-Y Gastric BypassCompletedNCT04859816Not applicable1 country
- Enteral Nutrition and Amino Acid AbsorptionCompletedNCT02590120Not applicable1 country
- Effects of Home Gluten Immunogenic Peptide Testing on Children With Celiac DiseaseSuspendedNCT03462979Not applicable1 country
- Three M Study (Malabsorption, Microbiota, Mini-Gastric Bypass)CompletedNCT03412149Not applicable1 country
- Protein-bound Versus Free Amino Acid Nutrition During INtestinal Malabsorption in Critical IllnessCompletedNCT04791774Not applicable1 country
- Intestinal Ultrasound Versus Double Balloon Enteroscopy (DBE) in Diagnosis of Malabsorption SyndromeStatus unknownNCT04777682Not applicable
- Microbial Basis of Systemic Malodor and "People Allergic To Me" ConditionsCompletedNCT03582826Not applicable2 countries
- Teen and Young Adult Connections for Support From Multidisciplinary Professionals & PeersCompletedNCT02987569Not applicable1 country
- Study of Safety, Tolerability, and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated With Common Variable ImmunodeficiencyCompletedNCT02199496Phase 1/21 country
- Market Research - Acceptability Study for a Range of MCT ProductsCompletedNCT04309149Not applicable1 country
- Market Research - Acceptability Study for New MCT Fat ProductsCompletedNCT04309214Not applicable1 country
- A Study to Monitor the Use of an Amino Acid-Based Infant FormulaCompletedNCT029532231 country
- Effect of Proprietary Botanical Blend on Glycemic Control and Post-prandial Carbohydrate AbsorptionStatus unknownNCT03897517Not applicable
- Immune System and Gut Abnormalities in Patients With Common Variable Immunodeficiency With and Without Gastrointestinal SymptomsCompletedNCT000154311 country
- A Study of the Safety, Efficacy and Tolerability of Nexvax-2 in Patients With Celiac Disease (CeD)Status unknownNCT03644069Phase 23 countries
- Bioequivalence Study of Nexvax2 in Subjects With Celiac DiseaseCompletedNCT03543540Phase 11 country
- Small Intestinal Absorption in Patients With Chronic Obstructive Pulmonary Disease and Cor PulmonaleCompletedNCT03243994Not applicable
- Use of a Peptide-based Formula in an Adult PopulationCompletedNCT02750787Not applicable1 country
- STA-5326 Meslylate to Treat Gut Inflammation Associated With Common Variable ImmunodeficiencyCompletedNCT00263237Phase 11 country
- Home Parenteral Nutrition (HPN) Families' Mobile Distance Connections to Care ResearchCompletedNCT01900288Not applicable1 country
- Fructose Malabsorption in Northern NorwayCompletedNCT00555191Phase 2/31 country
- Prospective Comparison Between SADI-S and Gastric BypassCompletedNCT027685061 country
- rHGH and Intestinal Permeability in Intestinal FailureCompletedNCT01380366Phase 41 country
- Investigate the Breath Hydrogen Exhalation After a Test Meal Containing Isomaltulose or Sucrose in InfantsStatus unknownNCT02247102Phase 31 country
- Detection of Celiac Disease in Patients With HypothyroidismCompletedNCT018625101 country
- Digestibility of Selected Resistant Starches in HumansCompletedNCT01939600Not applicable1 country
- A Study of the Efficacy and Tolerability of Pancrelipase Microtablet (MT) Capsules for the Treatment of Cystic Fibrosis-dependent Exocrine Pancreatic InsufficiencyCompletedNCT00662675Phase 32 countries
- Control of Steatorrhea in Participants With Cystic Fibrosis and Exocrine Pancreatic InsufficiencyCompletedNCT01327703Phase 42 countries
- Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?CompletedNCT00911612Phase 21 country
- Vitamin D Substitution for Patients With Chronic Pancreatitis and MalabsorptionCompletedNCT01141998Not applicable1 country
- Validation of Breath Tests in Diagnosing Small Bowel Bacterial OvergrowthCompletedNCT008720921 country
- Plasma Citrulline Concentration in Tropical EnteropathyCompletedNCT008168421 country