Short Bowel Syndrome clinical trials
The registry lists 159 studies for Short Bowel Syndrome across more than 10 countries. 24 are recruiting or about to start. 127 of them are mainly about Short Bowel Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-28.
Get an email when these change. Save the Short Bowel Syndrome studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Shire (15) · Takeda (10) · Boston Children's Hospital (9) · Zealand Pharma (7) · Mayo Clinic (5) · Jinling Hospital, China (5) · VectivBio AG (4) · University of Nebraska (4)
What is being tested here
Drugs under test in Short Bowel Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Teduglutide | 1 | 16 | 20 |
| Glepaglutide | 1 | 6 | 7 |
| Apraglutide | 1 | 3 | 6 |
| Human Growth Hormone | 1 | 1 | 4 |
| HM15912 | 1 | 0 | 1 |
| Amoxicillin | 1 | 0 | 1 |
| Levofloxacin | 1 | 0 | 1 |
| Ofloxacin | 1 | 0 | 1 |
| Fish oil triglycerides | 0 | 3 | 5 |
| Fish Oils | 0 | 3 | 5 |
Drug classes tested here GLP-1 receptor agonists 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027A Study of Teduglutide in Chinese Adults With Short Bowel Syndrome · Phase 3 · Takeda
- Oct 2027Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome. · Phase 3 · VectivBio AG
- Jan 2027SBS DISK- Creation of a Quality of Life Tool for Short Bowel Patients Compared With a Validated Quality of Life Questionnaire (SBS QoL) · Hospices Civils de Lyon
- Mar 2027Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC) · Napo Therapeutics, S.p.A.
- Apr 2027Successful Fiber Food Introduction in Short Bowel Syndrome · University of Texas Southwestern Medical Center
- Apr 2027A Clinical Study of FT1 in Patients With Short Bowel Syndrome · Chongqing Peg-Bio Biopharm Co., Ltd.
- Apr 2027Phase IV Study of rhGH Injection in Adult Short Bowel Syndrome · Changchun GeneScience Pharmaceutical Co., Ltd.
- Apr 2027A Study of Teduglutide in Chinese Children and Teenagers With Short Bowel Syndrome · Takeda
- Jun 2027A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB · Boston Children's Hospital
- Jul 2027AGE Accumulation in Patients on Long-term Parenteral Nutrition · University Hospital, Bordeaux
Who these studies take
Of the 18 Short Bowel Syndrome studies recruiting now, 8 (44%) set no upper age limit and 8 (44%) stop at 75 or younger. 9 (50%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (11%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (44%) | 8 (44%) |
| 18 | 15 (83%) | 15 (83%) |
| 30 | 12 (67%) | 12 (67%) |
| 40 | 12 (67%) | 12 (67%) |
| 50 | 12 (67%) | 12 (67%) |
| 65 | 12 (67%) | 12 (67%) |
| 75 | 10 (56%) | 10 (56%) |
| 85 | 10 (56%) | 10 (56%) |
Across all 159 studies, recruiting or not: 42% stop at 75 or younger and 36% at 65; 48% take children; 0% are for women only and 1% for men only; 13% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Short Bowel Syndrome studies take
Of 27 phase 3 interventional studies under Short Bowel Syndrome, half reached primary completion within 37 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 37 mo24–46 · 27 studies | 36 mo20–45 · 26 studies | — |
| Interventional, no phase | 22 mo19–59 · 24 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 159. Browse all 159 → or search them.
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT017931681 country
- Efficacy and Safety of TRA16 Administered Orally in Patients With Enteric Hyperoxaluria (EH).Not yet recruitingNCT07871669Phase 2
- Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBSRecruitingNCT07197944Phase 314 countries
- Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF SubjectsRecruitingNCT04775706Phase 28 countries
- A Feasibility Study to Evaluate Safety and Probable Benefit of the Eclipse XL1 System for Distraction Enterogenesis in Adult and Pediatric Patients With Short Bowel SyndromeRecruitingNCT05535361Not applicable1 country
- A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)RecruitingNCT07742735Phase 322 countries
- A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORBRecruitingNCT03530852Not applicable1 country
- AGE Accumulation in Patients on Long-term Parenteral NutritionRecruitingNCT07392801Not applicable1 country
- Resting Energy Expenditure by Gastrointestinal Functional StatusRecruitingNCT07714499Not applicable1 country
- A Clinical Study of FT1 in Patients With Short Bowel SyndromeRecruitingNCT07704047Phase 21 country
- Fiber Food Introduction in Pediatric Short Bowel SyndromeRecruitingNCT05432648Not applicable1 country
- Phase IV Study of rhGH Injection in Adult Short Bowel SyndromeRecruitingNCT07691125Phase 41 country
- A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORBEnrolling by invitationNCT056357471 country
- Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)RecruitingNCT06904872Phase 22 countries
- Role of the Microbiota in Intestinal Adaptation During Short Bowel SyndromeNot yet recruitingNCT07530055Not applicable
- Prospective Multisite Study of Quality of Life in Pediatric Intestinal FailureRecruitingNCT046290142 countries
- A Study of Teduglutide in Chinese Children and Teenagers With Short Bowel SyndromeRecruitingNCT073198321 country
- SBS DISK- Creation of a Quality of Life Tool for Short Bowel Patients Compared With a Validated Quality of Life Questionnaire (SBS QoL)RecruitingNCT067715051 country
- TED_ORG: Study on Short Bowel SyndromeRecruitingNCT07400783Not applicable1 country
- Palliative Care Needs of Children With Rare Diseases and Their FamiliesEnrolling by invitationNCT06938542Not applicable1 country
- Successful Fiber Food Introduction in Short Bowel SyndromeEnrolling by invitationNCT06240065Not applicable1 country
- Effect of Parenteral Support on FibroScan in Short Bowel SyndromeNot yet recruitingNCT072060041 country
- Absorption of Antibiotics With High Oral Bioavailability in Short-bowel SyndromeRecruitingNCT05302531Phase 11 country
- Efficacy Evaluation of UCB-MNCs in the Treatment of Refractory Neonatal DiseasesRecruitingNCT06427642Not applicable1 country
- Efficacy and Safety of PJ009 in Patients With Short Bowel Syndrome Requiring Parenteral NutritionActive, not recruitingNCT06512584Phase 31 country
- Pharmacokinetics of Apixaban in Patients With Short Bowel Syndrome Requiring Long Term Parenteral NutritionCompletedNCT04344717Phase 41 country
- A Survey to Assess Participants' and Physicians' Knowledge When Using GATTEX (Knowledge Assessment Survey)CompletedNCT055616471 country
- Registry for Participants With Short Bowel SyndromeActive, not recruitingNCT019900401 country
- Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBSCompletedNCT03905707Phase 39 countries
- Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension TrialCompletedNCT04881825Phase 38 countries
- A Study of Teduglutide in Chinese Adults With Short Bowel SyndromeActive, not recruitingNCT06973304Phase 31 country
- Open-Label Pilot Study With Crofelemer in Patients With Short Bowel SyndromeActive, not recruitingNCT06326645Early Phase 11 country
- A Study of Teduglutide in Japanese People With Short Bowel SyndromeCompletedNCT050233821 country
- Efficacy and Safety Evaluation of Glepaglutide in Treatment of Short Bowel SyndromeActive, not recruitingNCT07228403Phase 37 countries
- Effect of GLP-1 on Intestinal Barrier Function in SBS-IF Patients: A Preliminary Exploration.CompletedNCT07297238Not applicable1 country
- Evaluation of the Efficacy and Safety of Recombinant Human Growth Hormone (rhGH) in the Treatment of Children With Short Bowel SyndromeCompletedNCT00169637Phase 31 country
- Use of Omegaven Fish Oil Emulsion for Parenteral Nutrition Associated Liver Disease in Infants and ChildrenCompletedNCT01194063Phase 31 country
- Gastrointestinal Hormone Secretion, Intestinal Permeability and Short Bowel SyndromeCompletedNCT07235670Not applicable1 country
- Functional Sucrase Deficiency in Short Bowel Syndrome Patients With Intestinal FailureTerminatedNCT04604275Phase 21 country
- Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral NutritionCompletedNCT04743960Not applicable1 country
- Specific Dietary Fibers May Enhance Colonic Adaptation in Short Bowel Syndrome Through Microbial and Metabolic Mechanisms That Drive Functional Compensation.CompletedNCT07186608Not applicable1 country
- Characterization of the Long-term Safety, Efficacy, and Pharmacodynamics Revestive® in the Management of Short Bowel Syndrome Pediatric PatientsCompletedNCT03562130Phase 41 country
- Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS)CompletedNCT03690206Phase 39 countries
- Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.Active, not recruitingNCT05018286Phase 318 countries
- Metabolic Balance Study of Apraglutide in Patients With Short Bowel Syndrome, Intestinal Failure (SBS-IF) and Colon-in-Continuity (CIC)CompletedNCT04964986Phase 22 countries
- Intralipid Versus SMOFlipid in HPN PatientsCompletedNCT03773237Not applicable1 country
- A Study of Teduglutide (Revestive®) in Participants With Short Bowel Syndrome (SBS) in CanadaCompletedNCT053710281 country
- Long-term Safety and Efficacy Study of Teduglutide in Pediatric Participants With Short Bowel Syndrome (SBS)CompletedNCT02954458Phase 36 countries
- Long-term Study of Teduglutide in Pediatric Subjects With Short Bowel Syndrome Who Completed the TED-C13-003 StudyCompletedNCT02949362Phase 32 countries
- Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IFCompletedNCT04627025Phase 318 countries