Liver Cirrhosis, Biliary: all 209 studies

Page 1 of 3. Open to participants first (45), then studies with results posted, then the rest; newest registration first within each.

• J-LINX: Japan LINerixibat eXtension StudyNot yet recruitingNCT07860710Phase 3
• Nemolizumab for the Treatment of Moderate to Severe Chronic Hepatic PruritusNot yet recruitingNCT07843420Phase 2
• Study of Seladelpar and Cilofexor in Participants With Primary Biliary CholangitisNot yet recruitingNCT07841977Phase 2
• Phase I/II Trial of Human Umbilical Cord Mesenchymal Stromal Cells for UDCA-Refractory Primary Biliary CholangitisNot yet recruitingNCT07795151Phase 1/2
• Study on Clinical and Pathological Features of Primary Biliary Cholangitis and Risk Factors Related to Disease ProgressionNot yet recruitingNCT07733882
• The Safety and Efficacy of Upadacitinib in Refractory Autoimmune Related Cholangitis and Atopic Dermatitis With Moderate to Severe ItchingNot yet recruitingNCT07678645Phase 2
• Using Digital Health Technology to Monitor Patients With Primary Biliary Cholangitis (PBC)Enrolling by invitationNCT07631442
• Austrian PBC RegistryRecruitingNCT07598669
• Elafibranor Pregnancy Surveillance Program: A Study to Evaluate the Safety of Elafibranor During PregnancyRecruitingNCT07556913
• Biochemical Response and Clinical Outcomes in Patients With PBCRecruitingNCT07449793
• Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA TherapyRecruitingNCT07424677Phase 3
• The Value of Spleen Stiffness Measurement in Patients With PBCNot yet recruitingNCT07319169Not applicable
• FIREFLY Trial: Fenofibrate Intervention---Randomized Evaluation in First-Line PBC TherapyRecruitingNCT07296458Phase 3
• A Study of CS0159 in Patients With PBC With Inadequate Response or Intolerance to UDCARecruitingNCT07282353Phase 3
• Long-Term Study to Evaluate the Safety and Efficacy in Participants With Primary Biliary Cholangitis of Saroglitazar Magnesium-V on Clinical OutcomesRecruitingNCT07216235Phase 3
• Early Diagnosis of Primary Biliary Cholangitis (PBC) in Patients With Positive Anti-Mitochondrial Antibodies (AMA) and Normal Alkaline Phosphatase (ALP)RecruitingNCT07205874
• RELIEF: Multimodal Prehabilitation to Treat Fatigue in Patients With Primary Biliary CholangitisRecruitingNCT07161245Not applicable
• PBC Long-term Outcomes StudyRecruitingNCT07149675
• Monitoring the Response of Combination Ursodiol and Seladelpar TreatmentNot yet recruitingNCT07122206
• Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver DiseaseRecruitingNCT06825559Phase 1
• Spanish Registry of Autoimmune and Cholestatic Liver Diseases (ColHai)RecruitingNCT06767605
• Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis: a Real World StudyRecruitingNCT06755541Phase 3
• Fenofibrate in Primary Biliary Cholangitis: a Real World StudyRecruitingNCT06755151Phase 3
• TH104 for the Treatment of Pruritus in Primary Biliary CholangitisNot yet recruitingNCT06733519Phase 2
• LEOPARD Prospective Validation Cohort 1RecruitingNCT06723275
• LEOPARD Training and Validation Data Collection StudyRecruitingNCT06675604
• A Multicenter, Randomized, Controlled Trial of Prednisone Combined With Ursodeoxycholic Acid in the Treatment of Primary Biliary Cholangitis With Moderate to Severe Interface Hepatitis CharacteristicsEnrolling by invitationNCT06591468Phase 2/3
• Liver-gut Axis Study Through Identification of Liver Disease-specific MicrobiomeRecruitingNCT06519162
• Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune DiseasesNot yet recruitingNCT06417398Early Phase 1
• Clinical Study on the Treatment of Elevated Total Bilirubin in Primary Biliary Cholangitis With Baobao Dan CapsuleNot yet recruitingNCT06371196Phase 4
• Fenofibrate in Patients With Primary Biliary Cholangitis (PBC)RecruitingNCT06365424Phase 2/3
• Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated CirrhosisRecruitingNCT06051617Phase 3
• A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary CholangitisRecruitingNCT06016842Phase 3
• Detection Program for Patients With Primary Biliary Cholangitis Lost in the SystemRecruitingNCT05919433
• Fenofibrate Combined With Ursodeoxycholic Acid in Subjects With Primary Biliary CholangitisRecruitingNCT05751967Phase 3
• Fenofibrate for Compensated Cirrhosis Patients With Primary Biliary CholangitisRecruitingNCT05749822Phase 2/3
• Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)AvailableNCT05448170
• National Database on Primary Biliary CholangitisRecruitingNCT05151809
• Clinical Research of Tapering UDCA in PBC Patients With a Complete ResponseRecruitingNCT04650243Phase 4
• Bezafibrate in Patients With Primary Biliary Cholangitis (PBC)RecruitingNCT04514965
• Prospective, Multicenter Cohort Study on Primary Biliary CholangitisRecruitingNCT04076527
• Biobank for Cholestatic Liver Diseases.RecruitingNCT03445585
• Swiss Primary Biliary Cholangitis Cohort StudyRecruitingNCT03146910
• sCD163 in PBC Patients - Assessment of Treatment ResponseRecruitingNCT02931513
• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168
• To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and BezafibrateTerminatedNCT06488911Phase 3Results posted
• Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing CholangitisCompletedNCT05525520Phase 2Results posted
• Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC PatientsCompletedNCT05292872Results posted
• Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBCCompletedNCT05239468Phase 2Results posted
• A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver StiffnessCompletedNCT05014672Phase 2Results posted
• An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)CompletedNCT04950764Phase 1Results posted
• Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)CompletedNCT04950127Phase 3Results posted
• RESPONSE: Response to Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Control to or an Intolerance to Ursodeoxycholic Acid (UDCA)CompletedNCT04620733Phase 3Results posted
• Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary CholangitisCompletedNCT04604652Phase 2Results posted
• Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBCTerminatedNCT04594694Phase 2Results posted
• Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)Active, not recruitingNCT04526665Phase 3Results posted
• A Study of Baricitinib (LY3009104) in Participants With Primary Biliary Cholangitis Who do Not Respond or Cannot Take UDCATerminatedNCT03742973Phase 2Results posted
• Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic ImpairmentTerminatedNCT03633227Phase 4Results posted
• ENHANCE: Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)CompletedNCT03602560Phase 3Results posted
• Early Identification of Myocardial Impairment in PBCCompletedNCT03545672Results posted
• A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary CholangitisCompletedNCT03394924Phase 2Results posted
• BRIDGE Device for Post-operative Pain ControlTerminatedNCT03265249Not applicableResults posted
• Study to Assess Safety & Efficacy of GKT137831 in Patients With Primary Biliary Cholangitis Receiving Ursodiol.CompletedNCT03226067Phase 2Results posted
• Safety, Tolerability, and Efficacy of Etrasimod (APD334) in Participants With Primary Biliary CholangitisTerminatedNCT03155932Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) and Inadequate Response to Ursodeoxycholic AcidCompletedNCT03124108Phase 2Results posted
• Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary CholangitisCompletedNCT03112681Phase 2Results posted
• Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary CholangitisCompletedNCT02966834Phase 2Results posted
• Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)CompletedNCT02955602Phase 2Results posted
• Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without CirrhosisTerminatedNCT02943447Phase 2Results posted
• Study to Evaluate the Effects of Two Doses of Seladelpar (MBX-8025) in Subjects With Primary Biliary Cirrhosis (PBC)TerminatedNCT02609048Phase 2Results posted
• A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC PatientsCompletedNCT02516605Phase 2Results posted
• Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary CholangitisTerminatedNCT02308111Phase 4Results posted
• Study of Abatacept (Orencia) to Treat Primary Biliary CirrhosisCompletedNCT02078882Phase 4Results posted
• Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary CirrhosisCompletedNCT01904058Phase 2Results posted
• Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CTCompletedNCT01879735Phase 1Results posted
• Phase 2 Study on Effects of Obeticholic Acid (OCA) on Lipoprotein Metabolism in Participants With Primary Biliary CirrhosisCompletedNCT01865812Phase 2Results posted
• Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary CirrhosisCompletedNCT01473524Phase 3Results posted
• A Study of Efficacy and Safety of Ustekinumab in Patients With Primary Biliary Cirrhosis (PBC) Who Had an Inadequate Response to Ursodeoxycholic AcidCompletedNCT01389973Phase 2Results posted
• Pentoxifylline for Primary Biliary CirrhosisCompletedNCT01249092Phase 2Results posted
• Use of Fenofibrate for Primary Biliary CirrhosisCompletedNCT00575042Phase 2Results posted
• Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)CompletedNCT00570765Phase 2Results posted
• Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)TerminatedNCT00550862Phase 2Results posted
• Initial Study of Rituximab to Treat Primary Biliary CirrhosisCompletedNCT00364819Phase 1/2Results posted
• Epidemiology of PrImary Biliary Cholangitis in SpainActive, not recruitingNCT07821463
• Deciphering the Self-antigen Specific T Cell Signature of Autoimmune Liver DiseasesCompletedNCT07784881
• Patients With Primary Biliary Cholangitis(PBC)Active, not recruitingNCT07629128
• Patients With Primary Biliary CholangitisActive, not recruitingNCT07573514Not applicable
• A Two-part Study to Investigate the Effects in Adults of Two Doses of Golexanolone in Patients With Primary Biliary Cholangitis (PBC) With Fatigue and Cognitive DysfunctionCompletedNCT07304843Phase 1/2
• Fenofibrate in Subjects With Primary Biliary Cholangitis (PBC)Active, not recruitingNCT07104201Early Phase 1
• A Study Describing Scratch and Sleep Patterns in Patients With Primary Biliary Cholangitis (Luminaria)CompletedNCT07049887
• A Study of the Pharmacokinetics and Safety of CS0159 in Subjects With Hepatic InjuryCompletedNCT06888115Phase 1
• eMPower MechanismsCompletedNCT06861465Not applicable
• Single Ascending Dose Study to Evaluate Safety Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 in Healthy Subjects and Patients (PBC/PSC)CompletedNCT06798454Phase 1
• A Study of Elafibranor in Adult Japanese Participants With Primary Biliary Cholangitis (PBC)Active, not recruitingNCT06730061Phase 3
• Obeticholic Acid Versus Placebo, in Combination with Ursodeoxycholic Acid in Patients with Primary Biliary CirrhosisCompletedNCT06715319Phase 3
• PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.Active, not recruitingNCT06604923
• A Pilot Study of Fenofibrate and Ursodeoxycholic Acid in the Treatment of Newly Diagnosed Primary Biliary CholangitisCompletedNCT06591455Early Phase 1
• A Study to Evaluate the Pharmacokinetics and Safety of K-808 (Pemafibrate) in Subjects With Primary Biliary Cholangitis With Compensated Cirrhosis and Without Cirrhosis.CompletedNCT06525311Phase 1
• A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing TreatmentActive, not recruitingNCT06447168
• Open-Label Extension Study of Saroglitazar Magnesium in Participants With Primary Biliary CholangitisActive, not recruitingNCT06427395Phase 3

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