Leukoplakia clinical trials
The registry lists 49 studies for Leukoplakia across more than 10 countries. 9 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-08-20.
Status
- Completed
- 27
- Recruiting
- 7
- Status unknown
- 6
- Terminated
- 5
- Not yet recruiting
- 2
- Withdrawn
- 1
Phase
- Phase 2
- 14
- Phase 1
- 7
- Phase 3
- 1
- Phase 4
- 1
Where
- United States
- 21
- Egypt
- 5
- Italy
- 4
- China
- 3
- India
- 3
- Taiwan
- 2
Who runs them
National Cancer Institute (NCI) (7) · Cairo University (3) · National Taiwan University Hospital (2) · Fayoum University (2) · University of Medicine and Dentistry of New Jersey (1) · University of Zagreb (1) · University of California, San Francisco (1) · Institute of Head and Neck Studies and Education, United Kingdom (1)
Studies
Recruiting first, then most recently updated. Showing 49 of 49 — search for more.
- Pembrolizumab in Treating Participants With LeukoplakiaRecruitingNCT03603223Phase 21 country
- AI-Assisted Endoscopy for Upper Aerodigestive Tract LesionsNot yet recruitingNCT075963553 countries
- Topical Imiquimod Treatment of Oral DysplasiaRecruitingNCT07210775Phase 1/21 country
- SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence TomographyRecruitingNCT063210031 country
- Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See ApproachRecruitingNCT04858100Not applicable1 country
- Analyzing Handprint Patterns to Predict Oral Cancer Risks: A Comparative StudyNot yet recruitingNCT06256809
- A Comparative Study on the Efficacy of AI Temperature-controlled Radiofrequency Technology and Electrical Stimulation in the Treatment of Vulvar LeukoplakiaRecruitingNCT05250466Not applicable1 country
- Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal CordsRecruitingNCT05688488Phase 1/21 country
- Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based ImmunoscoreRecruitingNCT039753221 country
- Vitamin A Status in Patients With Vocal Fold LeukoplakiaActive, not recruitingNCT053232921 country
- Biomarkers for Oral CancerCompletedNCT003414971 country
- Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image AnalysisCompletedNCT063255141 country
- Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant LesionsTerminatedNCT05536037Phase 11 country
- Safety and Efficacy of Nivolumab in Treating Oral Proliferative Verrucous LeukoplakiaCompletedNCT03692325Phase 21 country
- Saliva and Plasma Exosomes for Oral Leukoplakia Malignant Transformation Diagnosis and Oral Cancer Prognosis MonitoringCompletedNCT064698921 country
- Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant LesionsCompletedNCT060870421 country
- Diagnostic Accuracy of lncRNA DQ786243 and miRNA146a in Saliva of Oral Potentially Malignant LesionsCompletedNCT057308551 country
- Intra and Extra Oral Inspection of Oral MucosaTerminatedNCT040794911 country
- Intralesional 5-fluorouracil Injection for the Treatment of Oral LeukoplakiaWithdrawnNCT05505539Phase 11 country
- Infectious Aetiology of Potentially Malignant Disorders and Squamous Cell Carcinomas of the Oral CavityCompletedNCT01636544Not applicable1 country
- Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral LeukoplakiaCompletedNCT00099021Phase 21 country
- Clinical Evaluation of the OncAlert RAPID in Subjects Presenting for Evaluation and/or Initial Biopsy; Impact on Decision-MakingCompletedNCT032398341 country
- Diagnostic Accuracy of Salivary Gamma-synuclein in Oral Malignant and Premalignant LesionsStatus unknownNCT04732741
- Candida Associated Cytokines in Oral LeukoplakiaCompletedNCT047129291 country
- A Randomized Study of Sulindac in Oral Premalignant LesionsCompletedNCT00299195Not applicable2 countries
- Oral Cancer Screening and Education in Hong KongStatus unknownNCT04487938
- Diagnostic Accuracy of Salivary DNA Integrity Index in Oral Malignant and Premalignant LesionsCompletedNCT036825621 country
- Oral Epithelial Dysplasia Informational Needs QuestionnaireCompletedNCT041532661 country
- Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral LesionsCompletedNCT042674191 country
- Evaluation of Effect of Topical Melatonin in Treatment of Oral LeukoplakiaStatus unknownNCT04251845Not applicable1 country
- Photodynamic Therapy With Metil 5-aminolevulinate for Actinic Cheilitis - Phase 2 Clinical TrialStatus unknownNCT03990636Phase 2
- Comparison or Rose Bengal and Toluidine Blue Staining for Lesion Detection EfficacyCompletedNCT03031899
- Natural History of Oro-pharyngeal Cancer PrecursorsCompletedNCT001793611 country
- Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral LeukoplakiaCompletedNCT03233165Not applicable
- Photodynamic Therapy for Oral Precursor LesionsCompletedNCT01497951Phase 31 country
- Tobacco Cessation Intervention Study for Oral DiseasesStatus unknownNCT02737176Not applicable1 country
- Pioglitazone for Oral Premalignant LesionsTerminatedNCT00951379Phase 23 countries
- Treatment of Oral Premalignant Lesions With 5-ALA PDTCompletedNCT00571974Phase 1/21 country
- Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral LeukoplakiaCompletedNCT00330382Phase 21 country
- Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Oral LeukoplakiaTerminatedNCT00571558Phase 11 country
- Aspirin Mouthwash in Treating Patients With Oral LeukoplakiaCompletedNCT01238185Phase 11 country
- Celecoxib in Preventing Head and Neck Cancer in Patients With Oral LeukoplakiaCompletedNCT00101335Phase 21 country
- Fenretinide in Treating Patients With Leukoplakia of the MouthCompletedNCT00004161Phase 21 country
- Rosiglitazone Maleate in Treating Patients With Oral LeukoplakiaCompletedNCT00369174Phase 21 country
- Photodynamic Therapy for Oral Leukoplakia and ErythroleukoplakiaCompletedNCT00155337Phase 41 country
- Least Invasive Nonlinear Light MicroscopyStatus unknownNCT007674421 country
- A Phase II Trial to Assess the Effects of Green Tea in Oral LeukoplakiaTerminatedNCT00176566Phase 21 country
- Randomized, Double Blind, Placebo-Controlled, Phase IIB Trial of Ketorolac Mouth Rinse Evaluating the Effect of Cyclooxygenase Inhibition on Oropharyngeal Leukoplakia: Collaborative Study of the NCI, NIDCD and the NIDCRCompletedNCT00001698Phase 21 country
- Treatment and Suppression of Hairy Leukoplakia in ARC Patients With Oral Acyclovir (ACV)CompletedNCT00002026Not applicable1 country