Joint Instability clinical trials
The registry lists 115 studies for Joint Instability across more than 10 countries. 21 are recruiting or about to start. 60 of them are mainly about Joint Instability (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03.
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Who runs them
Gazi University (4) · Istituto Ortopedico Rizzoli (4) · University of Southern Denmark (4) · Aesculap AG (3) · University of Calgary (3) · Peter Brehm GmbH (3) · Peking University Third Hospital (3) · Hacettepe University (2)
What is being tested here
Drugs under test in Joint Instability studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Glucose | 1 | 0 | 2 |
| Platelet rich plasma | 1 | 0 | 1 |
| Doxycycline | 1 | 0 | 1 |
| Dimethyl sulfone | 0 | 0 | 1 |
| Ketorolac | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Arthroscopic Versus Open Brostrom for Ankle Instability · Federal University of São Paulo
- Dec 2026Frequency of Hypermobility-Related Problems in Patients With Anorexia Nervosa · Vastra Gotaland Region
- Feb 2027Stabilization Exercises for Young Adults With Habitual Knuckle Cracking · Borna Farhoomand
- May 2027Hamstring Strengthening in Hypermobile Conditions · University of Calgary
- Sep 2027A Study on Associations Between Multidimensional Human Phenotypic Traits and Human Growth and Development · Nanfang Hospital, Southern Medical University
Who these studies take
Of the 13 Joint Instability studies recruiting now, 2 (15%) set no upper age limit and 11 (85%) stop at 75 or younger. 3 (23%) take children under 18. 1 (8%) are for women only and 1 (8%) for men only; 3 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (8%) | 1 (8%) |
| 18 | 12 (92%) | 12 (92%) |
| 30 | 10 (77%) | 9 (69%) |
| 40 | 10 (77%) | 9 (69%) |
| 50 | 9 (69%) | 8 (62%) |
| 65 | 4 (31%) | 3 (23%) |
| 75 | 2 (15%) | 2 (15%) |
| 85 | 2 (15%) | 2 (15%) |
Across all 115 studies, recruiting or not: 72% stop at 75 or younger and 70% at 65; 28% take children; 10% are for women only and 5% for men only; 37% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Joint Instability studies take
Of 41 interventional studies with no phase under Joint Instability, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 15 mo7–60 · 41 studies | — | 15 mo8–37 · 36 studies |
| Observational | 7 mo3–35 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
- Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle InstabilityOct 16, 2026NCT07878312
Studies
Recruiting first, then most recently updated. Showing 50 of 115. Browse all 115 → or search them.
- A Study on Associations Between Multidimensional Human Phenotypic Traits and Human Growth and DevelopmentRecruitingNCT078577981 country
- Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle InstabilityNot yet recruitingNCT07878312Not applicable1 country
- Regenerative Medicine for Joint Hypermobility and InstabilityNot yet recruitingNCT07688096Phase 1/2
- Stabilization Exercises for Young Adults With Habitual Knuckle CrackingNot yet recruitingNCT07815717Not applicable
- Frequency of Hypermobility-Related Problems in Patients With Anorexia NervosaEnrolling by invitationNCT071598671 country
- Comparative Effects of Closed Kinetic Chain Exercises and Thrower's Ten Exercises in Glenohumeral InstabilityRecruitingNCT07724977Not applicable1 country
- Effect of Core Stability Training With Foot Exercises in Chronic Ankle Instability PatientsRecruitingNCT07731035Not applicable1 country
- Clinical Outcomes Study of the Nexel Total ElbowRecruitingNCT02469662Not applicable8 countries
- Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Revision Hip Prosthesis SystemRecruitingNCT076532951 country
- Neurocognitive Loading Following Anterior Shoulder Stabilization: A Randomized Controlled TrialNot yet recruitingNCT07631819Not applicable
- Hamstring Strengthening in Hypermobile ConditionsNot yet recruitingNCT07626957Not applicable1 country
- Comparison of MBR + Suture Tape and MBR for CLAI : A Prospective Cohort StudyRecruitingNCT068972931 country
- Characteristics of the Functional State of the Musculoskeletal System, Body Awareness, and Quality of Life in Individuals With Joint Hypermobility, Their Associations, and Guidelines for Intervention.Enrolling by invitationNCT074769761 country
- Investigation of Medial Longitudinal Arch and Foot Function in Patients With LipedemaRecruitingNCT072940141 country
- Functional Instability in Patients Suffering From Collagen Disease and Joint HypermobilityRecruitingNCT058712161 country
- Ultrasonographic Evaluation of the Ulnar Nerve in Individuals With and Without Generalized Joint HypermobilityNot yet recruitingNCT070449861 country
- The Clinical Outcomes of the Modified Broström vs Anatomic Reconstruction Operation in CLAI and GJLRecruitingNCT051969061 country
- Spinal and Supraspinal Control in Chronic Ankle InstabilityRecruitingNCT06898554Not applicable1 country
- Arthroscopic Versus Open Brostrom for Ankle InstabilityRecruitingNCT03643926Not applicable1 country
- Effects of Textured Insoles and Exercise in Children With Joint HypermobilityRecruitingNCT06350240Not applicable1 country
- The Effect of Wii Fit Rehabilitation in Patients With Chronic Ankle Instability a Randomized Control StudyRecruitingNCT05957965Not applicable1 country
- ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty PopulationActive, not recruitingNCT03153449Not applicable10 countries
- Evaluation of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee ArthroplastyActive, not recruitingNCT046180162 countries
- Whole-Body Vibration and Postural Stability in Painful HSDActive, not recruitingNCT07830589Not applicable1 country
- Exercise in Patients With Hypermobile Joints and Knee PainActive, not recruitingNCT06277401Not applicable1 country
- Joint Hypermobility and Associated Factors in Patients With LipedemaCompletedNCT078082421 country
- Anterior Shoulder Instability Treated With a Semitendinosus Subscapular Sling ProcedureActive, not recruitingNCT03424421Not applicable1 country
- Effect of Kinesio-taping With Routine Physical Therapy in Wrist Joint HypermobilityCompletedNCT07639918Not applicable1 country
- Hypermobility, Foot Posture, and Scoliosis SeverityCompletedNCT072495411 country
- Evaluation of Benign Joint Hypermobility and Serum Prolidase Levels in Children Diagnosed With Attention-Deficit/Hyperactivity Disorder (ADHD) Compared to Healthy ControlsCompletedNCT076633831 country
- STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad TendonActive, not recruitingNCT03935750Not applicable8 countries
- Evaluation of Anterior Tibial Translation of the Knee in Healthy Women, at Two Times of the Menstrual Cycle, on Hormonal Contraceptives or Not (FLEX)CompletedNCT05177549Not applicable1 country
- Exercise and Lumbopelvic Mobility in PregnancyCompletedNCT07447466Not applicable1 country
- Impact of Hyperarch Fascia Training on Ankle Health and Exercise PerformanceCompletedNCT06959472Not applicable1 country
- Sleep Characteristics in Infants With Joint HypermobilityCompletedNCT071211791 country
- Identifying the Determinants of Bleeding and Hypermobility in Patients With Heavy Menstrual BleedingTerminatedNCT056851991 country
- Prenatal Pilates and Postpartum Ligamentous LaxityCompletedNCT073448571 country
- Prenatal Hormonal Markers and Sleep Characteristics in Young Adults With Joint HypermobilityCompletedNCT071579301 country
- IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and DysmorphismsCompletedNCT05763901Not applicable1 country
- Improvement of Fatigue in Unstable Shoulder Through a Therapeutic Exercise Program in PhysiotherapyCompletedNCT05443295Not applicable1 country
- Fitness Integrative Training for Pediatric Rheumatology DisordersCompletedNCT06556992Not applicable1 country
- Tight-Rope Augmented Adams Berger Technique for Distal Radioulnar Joint InstabilityCompletedNCT07080255Not applicable1 country
- Joint Hyperlaxity and Volar Plate Dynamics: MRI-Based Comparative Evaluation of the PIP JointCompletedNCT070820751 country
- The Effect of Lower Extremity Rotational Profile on Postural Control, Muscle Strength, Functional Capacity and Lower Extremity Function in Children With Generalized Joint HypermobilityCompletedNCT069985631 country
- Effects of Pilates Exercises on Laxity in Pregnant WomenCompletedNCT06684002Not applicable1 country
- Morphologic and Biomechanical Analysis of the Carpal LigamentsCompletedNCT02401568Not applicable1 country
- Is the Combine Prolotherapy More Effective Than the Traditional Prolotherapy in Patients With Temporomandibular Joint Hypermobility?CompletedNCT07020455Phase 41 country
- Sensorimotor Organization in Individuals With General Joint HypermobilityCompletedNCT06988631Not applicable1 country
- Quantitative MRI of Glenohumeral Cartilage & Labrum in Shoulder InstabilityCompletedNCT054311141 country
- Brace Efficiency and Generalized Joint HypermobilityCompletedNCT060213141 country