An interventional study of Hyperarch Fascia Training in Ankle Injuries, Sprains and Strains and Joint Instability, sponsored by Applied Science & Performance Institute. Completed at 1 site in United States. Open to participants aged 20 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-03-02.
Sponsored by Applied Science & Performance Institute · Not applicable, Interventional, and Treatment
The purpose of this clinical trial is to evaluate whether the Hyperarch Fascia Training (HFT) program can reduce ankle pain and improve jump performance in active adults aged 20-45 with a history of ankle sprains. Participants will be randomly assigned to either an HFT intervention group or a control group, maintaining regular activity. Over 12 weeks, participants will complete remote training sessions, track jump performance using the "My Jump Lab" app, and complete ankle pain and stability questionnaires. All activities and assessments will be conducted remotely with guidance from certified coaches.
This is a decentralized, randomized controlled trial evaluating the effects of Hyperarch Fascia Training (HFT) on pain and functional outcomes in adults aged 20-45 with a history of chronic ankle sprains. Up to 62 participants will be remotely recruited across the United States, with a target of 50 completing the study. Participants will be randomized to either an HFT intervention group or a passive control group, maintaining usual activity. The HFT group will complete three training sessions per week (one live virtual session and two self-guided sessions) over a 12-week period. Outcomes will assess pain and self-reported functional improvement using validated questionnaires and remote performance measures. All study activities, including recruitment, training, and assessments, will be conducted virtually.
350 studies on the registry are indexed under Ankle Injuries; 74 are open to participants now.
This study's enrollment of 62 is above the median of 54 across 270 interventional studies indexed under Ankle Injuries.
Browse Ankle Injuries studies →Applied Science & Performance Institute is the lead sponsor of 23 studies on the registry; 2 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Hepatitis B is a virus that infects the liver. These are separate tests: HBsAg positive usually means a current infection (a recent vaccination can briefly cause it too); total anti-HBc (HBcAb) positive means an infection now or in the past; HBV DNA measures how much virus is in the blood.
Some studies accept a past infection if HBV DNA is undetectable, sometimes with antiviral medicine during the study. Check what this study allows.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A drug or device being studied in a clinical trial.
It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hepatitis B tests
Hepatitis B is a virus that infects the liver. These are separate tests: HBsAg positive usually means a current infection (a recent vaccination can briefly cause it too); total anti-HBc (HBcAb) positive means an infection now or in the past; HBV DNA measures how much virus is in the blood.
Some studies accept a past infection if HBV DNA is undetectable, sometimes with antiviral medicine during the study. Check what this study allows.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Investigational drug or device
A drug or device being studied in a clinical trial.
It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants in this group will undergo a 12-week Hyperarch Fascia Training (HFT) program targeting foot and ankle fascial health. The protocol includes one weekly live 1-hour virtual session with a certified HFT coach and two independent 1-hour training sessions.
Behavioral: Hyperarch Fascia Training
Participants in the control group will be instructed to maintain their usual activities of daily living (ADL) over the 12-week study period. They will not engage in any structured intervention or new rehabilitation protocol.
A 12-week behavioral intervention involving Hyperarch Fascia Training (HFT), which includes one weekly 1-hour virtual session with a certified coach and two 1-hour independent training sessions. The protocol combines meditation, mental imagery, foot and toe strengthening exercises, myofascial rolling, balance drills, and low-impact plyometrics.
Change in Aggregate Score on Cumberland Ankle Instability Tool (CAIT)
The CAIT is a 9-item self-reported questionnaire used to measure perceived ankle instability. Scores range from 0-30, with lower scores indicating greater instability.
Time frame: Baseline (Week 0), Week 8, and Week 12
Change in Aggregate Score on Foot and Ankle Ability Measure (FAAM)
The FAAM assesses functional ability with two subscales: Activities of Daily Living (ADL) and Sports. Each item is scored from 0 (unable to perform) to 4 (no difficulty), with higher scores indicating better function.
Time frame: Baseline (Week 0), Week 8, and Week 12
Change in Countermovement Jump (CMJ) Performance
The performance measures for CMJ will include: Jump height, flight time, force, velocity, and power. Testing will begin with a standardized warm-up consisting of two sets of 10 bodyweight squats, with \~30 seconds of rest between each set. After warming up, participants will perform two maximal CMJs at their perceived maximal effort, with the highest performance being used as the outcome score. Data collection will involve recording all jumps using a mobile phone camera mounted on a tripod to capture motion in the frontal plane. The recordings will utilize artificial intelligence algorithms for markerless motion tracking at 60 Hz with a resolution of 1080p, processed through the previously validated "My Jump Lab" mobile application. To register CMJ performance, participants will be instructed to place their hands on their hips, look directly at the camera, and remain steady until the recording begins and then perform a maximal CMJ.
Time frame: Baseline (Week 0), Week 8, and Week 12
Change in Aggregate Score on Short Form Health Survey (SF-12)
The SF-12 measures quality of life across physical and mental health domains. Higher scores indicate better well-being .Question responses range from 1 to 5 or from 1 to 6 and each response is converted to a score from 0 to 100. For all questions, higher scores demonstrated greater well-being.
Time frame: Baseline (Week 0), Week 8, and Week 12
Glute Activation via Elevated Towel Curls
Participants will self-assess glute activation following the performance of elevated towel curls. At the end of this exercise, subjects rate below on a scale of 1-10 how much they feel this exercise activates (causes muscular tension) in their glutes. With 1 being no glute activation (no glute muscle tension) and 10 being complete glute activation (extreme glute muscle tension).
Time frame: Baseline (Week 0), Week 8, and Week 12
Frequency and Nature of Adverse Events
Self-reported or observed adverse events will be recorded and assessed for severity, causality, and frequency across both groups.
Time frame: Continuous throughout the 12-week intervention
Plan to share: No
Ran from May 2025 to primary completion in Dec 2025, 7 months.
Of 141 interventional studies with no phase under Ankle Injuries, half reached primary completion within 9 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 31. This study's 7 months is below that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.
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