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CompletedNCT07249541AISUpdated Jun 26, 2026

Hypermobility, Foot Posture, and Scoliosis Severity

An observational study in Joint Hypermobility, Adolescent Idiopathic Scoliosis and Foot Posture, sponsored by Istinye University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 10 Years to 19 Years. Per ClinicalTrials.gov, last updated 2026-06-26.

Sponsored by Istinye University · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
22
Ages
10 Years to 19 Years
Sex
All
01

Study summary

Adolescent Idiopathic Scoliosis is a three-dimensional spinal deformity that may also affect joint mobility, lower limb alignment, and overall posture. Joint hypermobility and foot posture abnormalities, including pronation or supination, are commonly observed in adolescents and may contribute to postural imbalance or altered biomechanical loading. However, the relationship between hypermobility, foot posture, and the severity of scoliosis remains unclear.

The aim of this study is to examine whether generalized joint hypermobility and foot posture characteristics are associated with Cobb angle severity in adolescents diagnosed with Adolescent Idiopathic Scoliosis. Hypermobility will be assessed using the Beighton Score, and foot posture will be evaluated with the Foot Posture Index. Understanding these associations may help clinicians better evaluate biomechanical factors related to scoliosis and guide future preventive or therapeutic approaches.

02

Conditions studied

  • Joint Hypermobility
  • Adolescent Idiopathic Scoliosis
  • Foot Posture

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03

In context

Joint Instability

115 studies on the registry are indexed under Joint Instability; 21 are open to participants now.

This study's enrollment of 22 is below the median of 60 across 54 observational studies indexed under Joint Instability.

Browse Joint Instability studies →

Lead sponsor

Istinye University is the lead sponsor of 221 studies on the registry; 94 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
10 Years to 19 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study population consists of adolescents aged 10 to 19 years who have been clinically and radiographically diagnosed with Adolescent Idiopathic Scoliosis. Participants must have a Cobb angle of at least 10° and be able to complete physical assessments, including hypermobility and foot posture evaluations.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Diagnosis of Adolescent Idiopathic Scoliosis
  • Age 10-19 years
  • Cobb angle ≥ 10° on standing Anterior-Posterior radiograph
  • Ability to participate in physical assessments
  • Voluntary consent to participate

Exclusion criteria

Exclusion Criteria:

  • Neuromuscular, syndromic, or congenital scoliosis
  • Previous spinal surgery
  • Lower extremity orthopedic conditions affecting foot posture
  • Neurological or rheumatological disorders affecting joint mobility
  • Communication or cognitive difficulties limiting participate
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
22 participants (actual)
Patient registry
No

Groups and cohorts

  • Adolescent Idiopathic Scoliosis Group

    Participants diagnosed with Adolescent Idiopathic Scoliosis will undergo assessments of hypermobility (Beighton Score), foot posture (Foot Posture Index), and scoliosis severity (Cobb angle).

    Other: Assessment

Interventions

  • OtherAssessment

    Participants diagnosed with Adolescent Idiopathic Scoliosis will undergo assessments of hypermobility (Beighton Score), foot posture (Foot Posture Index), and scoliosis severity (Cobb angle).

06

What researchers measure

Primary outcomes

  1. Foot Posture Index-6

    The Foot Posture Index-6 is a reliable and valid clinical assessment tool used to objectively evaluate foot posture in the pronation-supination spectrum. The assessment is performed with the individual in a relaxed standing position and is based on six observational criteria. The total score ranges from -12 to +12, where higher scores indicate a more pronated foot posture, while lower scores reflect a more supinated posture. A score close to 0 represents a neutral foot posture.

    Time frame: 4 weeks

  2. The Beighton Test

    This is a standardized and easily applicable clinical assessment method used to determine joint hypermobility. The total score for the nine-item test ranges from 0 to 9. A total score of ≥4 indicates the presence of hypermobility. It is scored out of 9 points; each positive finding is evaluated as 1 point.

    Time frame: 4 weeks

Secondary outcomes

  1. Feiss Line Test

    Used to evaluate the structural characteristics of the arch of the foot. In this test, the position of the navicular tubercle above or below a line drawn by aligning the medial malleolus, navicular tubercle, and first metatarsal head indicates the presence of pes planus or pes cavus.

    Time frame: 4 weeks

  2. Sit-Reach Test

    This is a common field test that evaluates the flexibility of the hamstring and lumbar muscles. The participant sits in a straight position, knees straight, and the soles of their feet touching the test box, reaching forward; the distance between their toes indicates the level of flexibility.

    Time frame: 4 weeks

07

Study locations

1 site
  • Istinye University
    Istanbul, 34010, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Dec 2025 to primary completion in Mar 2026, 3 months.

Of 22 observational studies under Joint Instability, half reached primary completion within 7 months of starting (the median), counting those still running; a quarter within 3 and three quarters within 35. This study's 3 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 18, 2025
First posted
Nov 25, 2025
StartActual
Dec 15, 2025
Primary completionActual
Mar 15, 2026
CompletionActual
Apr 30, 2026
Last update
Jun 26, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 26, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07249541
Lead sponsor
Istinye University
Responsible party
Tuğçe Yavuz (Principal Investigator, Istinye University) — Principal investigator
First posted
Nov 25, 2025
Start date
Dec 15, 2025
Primary completion
Mar 15, 2026
Completion
Apr 30, 2026
Last update
Jun 26, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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