ClinicalTrials.gg
CompletedNCT07639918Updated Jul 8, 2026

Effect of Kinesio-taping With Routine Physical Therapy in Wrist Joint Hypermobility

An interventional study of Routine Physical Therapy Protocol for Wrist Joint and Kinesio Taping (Y-strip Technique) in Wrist Joint Hypermobility, sponsored by University of Lahore. Completed at 1 site in Pakistan. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-07-08.

Sponsored by University of Lahore · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Sep 2025, registered May 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
All
01

Study summary

The study will be randomized controlled trial. This study will be conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan. This will investigate the effects of routine physical therapy with and without Kinesio taping in patients with Wrist Joint Hypermobility. A sample size of 38 participants will be randomly assigned into two groups. Group A will receive routine physical therapy protocol, while Group B will receive the same protocol with additional Kinesio taping. The interventions will be delivered three times per week for 8 weeks. Clinical outcomes, including pain, range of motion, and functionality, will be assessed at baseline and after 8 weeks using standardized tools.

Read the detailed description

Screening: All participants will be screened according to inclusion and exclusion criteria. Eligible individuals will provide written informed consent prior to participation.

Randomization \& Allocation: Participants will be randomized into two groups using the lottery method.

Blinding: This will be a single-blind study in which the assessor will be blinded to group allocation.

Group A (Control): Participants will receive routine physical therapy treatment including Transcutaneous Electrical Nerve Stimulation (TENS), cryotherapy (if swelling), splinting recommendations, passive or active Range of Motion (ROM), strengthening, proprioceptive, dynamic and functional training exercises. Sessions will last 45 minutes, 3 times per week for 8 weeks.

Group B (Experimental): Participants will receive the same routine physical therapy protocol, plus Kinesio taping (Y-strip method) applied to the wrist joint. Each session will last 45 minutes, 3 times per week for 8 weeks.

Outcome Variables:

  1. Pain will be measured with the Numeric Pain Rating Scale (NPRS).
  2. Wrist Functionality with the Patient-Rated Wrist Evaluation (PRWE)
  3. Wrist range of motion with a universal Goniometer. Assessments will be done at baseline and after 8 weeks.
02

Conditions studied

  • Wrist Joint Hypermobility

Browse trials for

Keywords

  • Wrist Instability
  • Kinesio Taping
  • Wrist Pain
  • Joint Hypermobility
03

In context

Joint Instability

115 studies on the registry are indexed under Joint Instability; 21 are open to participants now.

This study's enrollment of 38 is below the median of 46 across 58 interventional studies indexed under Joint Instability.

Browse Joint Instability studies →

Lead sponsor

University of Lahore is the lead sponsor of 232 studies on the registry; 41 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Male and female participants
  • Aged 18 to 40 years.
  • Beighton score greater than or equal to 4 either less than 4 with positive family history of hypermobility
  • Intermittent or persistent wrist pain in one or both hands for more than 3 years.
  • Passive range of motion less than 50 degree in wrist extension

Exclusion criteria

Exclusion Criteria:

  • Surgical history on wrist joint and upper limb in past 12 months.
  • Inflammatory and infectious joint diseases like rheumatoid arthritis, wrist OA.
  • Acute trauma or neurological conditions including radiculopathy, plexopathy, tunnel syndromes.
  • Current or past use of splints or pain-related medications.
  • Medication influencing joint mobility including , HRT, lipid-lowering drugs.
  • Pregnant women and those less than 1 year postpartum
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
38 participants (actual)

Study arms

  • Active comparator
    A - Control (Routine Physical Therapy)

    Participants in this arm will receive the routine physical therapy protocol for wrist joint hypermobility. Treatment includes pain-modality management (Transcutaneous Electrical Nerve Stimulation (TENS) or cryotherapy depending on swelling), wrist joint passive and active range of motion exercises, strengthening exercises, proprioceptive training, dynamic strengthening, grip training, and task-specific functional exercises. A structured home-exercise plan is also provided.

    Other: Routine Physical Therapy Protocol for Wrist Joint

  • Experimental
    B - Experimental (Routine Physical Therapy with Kinesio Taping)

    Participants in this arm will receive the same routine physical therapy protocol as Arm 1, with the addition of Kinesio taping applied to the wrist using a standardized "Y-strip" method. Kinesio tape is applied in the final 10 minutes of each session.

    Device: Kinesio Taping (Y-strip Technique)

Interventions

  • OtherRoutine Physical Therapy Protocol for Wrist Joint

    The routine physical therapy protocol includes: Transcutaneous Electrical Nerve Stimulation (TENS): 10 minutes (80 Hz, pulse width 50-100 µs); avoided if swelling is present. Cryotherapy: Used when swelling is present. Splinting: Static splints recommended for rest or night; dynamic splints for activity (as needed). Passive \& Active Range of Motion (ROM) Exercises: Flexion, extension, radial and ulnar deviation (3 sets of 7 repetitions). Manual Resistance Strengthening: Flexion, extension, radial and ulnar deviation (3 sets of 10 repetitions). Wrist Curls and Reverse Wrist Curls: 0.5-1 kg weight (3 sets of 7 repetitions). Proprioceptive Training: Wrist circles, tendon gliding (3 sets of 10 repetitions). Dynamic Strengthening: Resistance band flexion and extension (3 sets of 12 repetitions). Grip Strengthening: Soft ball/Thera putty (3 sets of 10 reps) Functional Training: Task-specific activities for 5 minutes. Frequency: 3 sessions per week for 8 weeks. Session Duration: 45 minutes

    Also known as: Intervention for Arm 1

  • DeviceKinesio Taping (Y-strip Technique)

    Kinesio taping will be applied in "Y" configuration using 5-cm elastic therapeutic tape. Procedure: 1. Tape Preparation: One base strip 10 cm Two tails 7-10 cm each 2. Application: Base Anchor: Placed over the carpal region above the wrist crease. Radial Tail: Applied along forearm/wrist flexors toward the thumb side. Ulnar Tail: Applied along extensor surface toward the little-finger side. 3. Aftercare: Patient checks wrist movement for comfort. Tape should remain dry for one hour post-application. Session details (combined): 45-minute sessions Heat pack or TENS for 10 minutes (if no swelling) ROM, strengthening, proprioception, dynamic training Tape applied in final 10 minutes Frequency: 3 sessions/week for 8 weeks A complete home-exercise program is also provided.

06

What researchers measure

Primary outcomes

  1. Numeric Pain Rating Scale (NPRS)

    The Numeric Pain Rating Scale (NPRS) is an 11 point scale used to assess wrist pain intensity, ranging from 0 to 10, where 0 indicates no pain and 10 indicates worst imaginable pain. Higher scores indicate greater pain intensity.

    Time frame: Baseline and at the end of 8 weeks

  2. Patient Rated Wrist Evaluation (PRWE)

    The Patient Rated Wrist Evaluation (PRWE) questionnaire is a self reported questionnaire used to assess wrist pain and functional disability. The total score ranges from 0 to 100, with higher scores indicating greater pain and disability.

    Time frame: Baseline and at the end of 8 weeks

  3. Wrist Range of Motion

    Wrist range of motion will be measured using a universal goniometer in degrees for wrist flexion, extension, radial deviation, and ulnar deviation. Higher values indicate greater wrist mobility.

    Time frame: Baseline and at the end of 8 weeks

07

Study locations

1 site
  • University of Lahore Teaching Hospital
    Lahore, Punjab Province 55150, Pakistan
08

References and documents

Publications

  • Farhadian M, Morovati Z, Shamsoddini A. Effect of Kinesio Taping on Pain, Range of Motion, Hand Strength, and Functional Abilities in Patients with Hand Osteoarthritis: A Pilot Randomized Clinical Trial. Arch Bone Jt Surg. 2019 Nov;7(6):551-560. PubMed 31970261 ↗
  • Daman M, Shiravani F, Hemmati L, Taghizadeh S. The effect of combined exercise therapy on knee proprioception, pain intensity and quality of life in patients with hypermobility syndrome: A randomized clinical trial. J Bodyw Mov Ther. 2019 Jan;23(1):202-205. doi: 10.1016/j.jbmt.2017.12.012. Epub 2017 Dec 15. PubMed 30691753 ↗
  • Kim GS, Weon JH, Kim MH, Koh EK, Jung DY. Effect of weight-bearing wrist movement with carpal-stabilizing taping on pain and range of motion in subjects with dorsal wrist pain: A randomized controlled trial. J Hand Ther. 2020 Jan-Mar;33(1):25-33. doi: 10.1016/j.jht.2019.02.001. Epub 2019 Mar 11. PubMed 30871958 ↗
  • Luder G, Aeberli D, Mebes CM, Haupt-Bertschy B, Baeyens JP, Verra ML. Effect of resistance training on muscle properties and function in women with generalized joint hypermobility: a single-blind pragmatic randomized controlled trial. BMC Sports Sci Med Rehabil. 2021 Feb 8;13(1):10. doi: 10.1186/s13102-021-00238-8. PubMed 33557909 ↗
  • Jung KS, Jung JH, Shin HS, Park JY, In TS, Cho HY. The Effects of Taping Combined with Wrist Stabilization Exercise on Pain, Disability, and Quality of Life in Postpartum Women with Wrist Pain: A Randomized Controlled Pilot Study. Int J Environ Res Public Health. 2021 Mar 30;18(7):3564. doi: 10.3390/ijerph18073564. PubMed 33808137 ↗
  • Chaiparinya P, Gaogasigam C. Prevalence, frontal plane knee alignment, and lower limb joint pain and injury in generalized joint hypermobility in Thai physical therapy students. Reumatologia. 2022;60(2):116-124. doi: 10.5114/reum.2022.115621. Epub 2022 May 18. PubMed 35782028 ↗
  • Chanthana P, Atthakomol P, Manosroi W, Wongpakaran T, Kraisarin J, Sananpanich K. Comparison of patient preferences and responsiveness among common patient-reported outcome measures for hand/wrist injuries or disorders. J Orthop Traumatol. 2023 Jan 9;24(1):2. doi: 10.1186/s10195-022-00681-4. PubMed 36622514 ↗
  • Ituen OA, Anieto EM, Ferguson G, Duysens J, Smits-Engelsman B. Prevalence and Demographic Distribution of Hypermobility in a Random Group of School-Aged Children in Nigeria. Healthcare (Basel). 2023 Apr 11;11(8):1092. doi: 10.3390/healthcare11081092. PubMed 37107926 ↗
  • Oruk DO, Karakaya MG, Yenisehir S, Karakaya IC. Effect of Kinesio taping on wrist kinematics and functional performance: A randomized controlled trial. J Hand Ther. 2023 Jan-Mar;36(1):3-12. doi: 10.1016/j.jht.2021.09.005. Epub 2021 Oct 27. PubMed 34756489 ↗
  • Campos-Villegas C, Perez-Alenda S, Carrasco JJ, Igual-Camacho C, Tomas-Miguel JM, Cortes-Amador S. Effectiveness of proprioceptive neuromuscular facilitation therapy and strength training among post-menopausal women with thumb carpometacarpal osteoarthritis. A randomized trial. J Hand Ther. 2024 Apr-Jun;37(2):172-183. doi: 10.1016/j.jht.2022.07.005. Epub 2022 Aug 7. PubMed 35948454 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Sep 2025 to primary completion in May 2026, 7 months.

Of 36 non-industry interventional studies with no phase under Joint Instability, half reached primary completion within 15 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 37. This study's 7 months is below that.

Counting every sponsor, half of 41 studies reached it within 15 months; a quarter within 7 and three quarters within 60.

How these figures are worked out, and which studies are left out of them.

Registered
May 13, 2026
First posted
Jun 10, 2026
StartActual
Sep 30, 2025
Primary completionActual
May 15, 2026
CompletionActual
Jun 15, 2026
Last update
Jul 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 8, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07639918
Responsible party
Sponsor
First posted
Jun 10, 2026
Start date
Sep 30, 2025
Primary completion
May 15, 2026
Completion
Jun 15, 2026
Last update
Jul 8, 2026

Study contacts

Hafiza Saliha Javed, MS-MSK
principal investigator · University of Lahore

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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