Intracranial Hypotension clinical trials
The registry lists 20 studies for Intracranial Hypotension across 9 countries. 7 are recruiting or about to start. 13 of them are mainly about Intracranial Hypotension (how this is decided). Per ClinicalTrials.gov, last updated 2026-08-12.
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Phase
- Phase 2
- 2
Who runs them
Duke University (3) · Beijing Tiantan Hospital (2) · University Hospital, Strasbourg, France (2) · Assistance Publique - Hôpitaux de Paris (2) · Ain Shams University (1) · University Health Network, Toronto (1) · Mayo Clinic (1) · Huashan Hospital (1)
What is being tested here
Drugs under test in Intracranial Hypotension studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Fibrin Tissue Adhesive | 0 | 0 | 1 |
| Hydroxyethyl Starch Derivatives | 0 | 0 | 1 |
| Whole blood | 0 | 0 | 1 |
Who these studies take
Of the 5 Intracranial Hypotension studies recruiting now, 5 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 5 (100%) | 5 (100%) |
Across all 20 studies, recruiting or not: 20% stop at 75 or younger and 15% at 65; 10% take children; 5% are for women only and 0% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 20 of 20. search them.
- A Clinical Registry of Spontaneous Intracranial HypotensionRecruitingNCT059225141 country
- CVFs in SIH: EID vs. PCD CTMRecruitingNCT07582744Not applicable1 country
- Autologous Platelet-rich Plasma Versus Whole Blood for Epidural Patch in Spontaneous Intracranial HypotensionNot yet recruitingNCT07602556Not applicable
- Greater Occipital Nerve Block for Spontaneous Intracranial HypotensionRecruitingNCT063745241 country
- Pathophysiology and Treatment of Cerebrospinal Hypotension Exploration StudyEnrolling by invitationNCT068055911 country
- The Blood Patch in the Management of Intracranial HypotensionRecruitingNCT064988041 country
- Spinal CSF Leaks in Chronic Subdural HematomaRecruitingNCT063234341 country
- ONSD Changes and Treatment Response After Epidural Blood Patch in Spontaneous Intracranial HypotensionCompletedNCT070852601 country
- Blind Versus Targeted Epidural Patch With Autologous Platelet-rich Plasma for Spontaneous Intracranial HypotensionWithdrawnNCT07283536Not applicable
- Optic Nerve Sheath Diameter in Postspinal HeadacheCompletedNCT069578991 country
- Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan DiseaseCompletedNCT051233391 country
- Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal AnesthesiaCompletedNCT050769291 country
- Spontaneous Intracranial Hypotension Treatment "SIHT"CompletedNCT02261792Not applicable1 country
- A Randomized Trial of CT Fluoroscopy-guided Targeted Autologous Blood and Fibrin Glue Patching for TreatmentCompletedNCT03276975Phase 21 country
- Low Intracranial Pressure Treatment Strategies for Chronic Subdural Hematoma PatientsStatus unknownNCT04607447Not applicable1 country
- Non-invasive Estimation of CSF Pressure Using MRI in Patients With Spontaneous Intracranial HypotensionCompletedNCT03041441Not applicable1 country
- Postoperative Changes in Optic Nerve Sheath Diameter in Patients Undergoing Spinal Anesthesia for Cesarean DeliveryStatus unknownNCT04301830
- HES Patch Versus Blood PatchCompletedNCT02570724Not applicable1 country
- Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous AccessCompletedNCT03276494Phase 21 country
- Pituitary Function and Spontaneous Intracranial HypotensionSuspendedNCT026035491 country