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Intervertebral Disc Degeneration clinical trials

The registry lists 462 studies for Intervertebral Disc Degeneration across more than 10 countries. 100 are recruiting or about to start. 368 of them are mainly about Intervertebral Disc Degeneration (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Intervertebral disc disease too: 509 studies, 111 open.

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Status

Completed
189
Recruiting
60
Status unknown
55
Terminated
53
Withdrawn
34
Active, not recruiting
28

Phase

Phase 2
42
Phase 1
32
Phase 3
25
Phase 4
17
Early Phase 1
2

Where

United States
232
Germany
29
France
18
China
17
Italy
14
Australia
13

Who runs them

Medtronic Spinal and Biologics (23) · NuVasive (20) · DePuy Spine (11) · Zimmer Biomet (9) · Orthofix Inc. (8) · Aesculap AG (6) · Rush University Medical Center (6) · Mesoblast, Ltd. (6)

What is being tested here

Drugs under test in Intervertebral Disc Degeneration studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
EC5026101
Cannabis sativa subsp. indica TOP101
Dexamethasone101
Rexlemestrocel-l012
Stem Cell012
Morphine012
Fibrin Tissue Adhesive022
Tranexamic Acid001
Oxycodone001
Autologous adipose derived mesenchymal stem cells (mscs)001

Drug classes tested here Opioids 4 · Local anesthetics 3

Coming up

7phase 3 studies under way
34studies finish main data collection within a year2 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 60 Intervertebral Disc Degeneration studies recruiting now, 29 (48%) set no upper age limit and 16 (27%) stop at 75 or younger. 7 (12%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (8%) take healthy volunteers.

Recruiting studies that take each age, of 60
AgeWomenMen
106 (10%)6 (10%)
1842 (70%)42 (70%)
3059 (98%)59 (98%)
4059 (98%)59 (98%)
5060 (100%)60 (100%)
6558 (97%)58 (97%)
7549 (82%)49 (82%)
8533 (55%)33 (55%)

Across all 462 studies, recruiting or not: 37% stop at 75 or younger and 18% at 65; 7% take children; <1% are for women only and 0% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Intervertebral Disc Degeneration studies take

Of 85 interventional studies with no phase under Intervertebral Disc Degeneration, half reached primary completion within 50 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase50 mo27–72 · 85 studies52 mo43–82 · 45 studies44 mo13–63 · 40 studies
Observational61 mo45–84 · 80 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Stopped1

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 462. Browse all 462 → or search them.