Herpes Simplex: all 302 studies

Page 2 of 4. Open to participants first (30), then studies with results posted, then the rest; newest registration first within each.

• Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years OldCompletedNCT00224484Phase 3Results posted
• A Study Comparing Daily Treatment With Valaciclovir To Placebo For Suppression Of Herpes Simplex Virus HSV-2 Genital Herpes In Newly Diagnosed Patients. VALTREX® Tablet is a Trademark of the GlaxoSmithKline Group of Companies.CompletedNCT00158860Phase 4Results posted
• Famciclovir Pediatric Formulation in Children 1 to 12 Years of Age With Herpes Simplex InfectionCompletedNCT00098059Phase 3Results posted
• HerpeVac Trial for Young WomenCompletedNCT00057330Phase 3Results posted
• Long Term Treatment of Herpes Simplex Encephalitis (HSE) With ValacyclovirCompletedNCT00031486Phase 3Results posted
• Acyclovir for Herpes Infections Involving the Central Nervous System in NeonatesCompletedNCT00031460Phase 3Results posted
• Acyclovir Herpes Simplex Virus (HSV) Skin, Eye, and MouthCompletedNCT00031447Phase 3Results posted
• Using Artificial Intelligence to Help Doctors Identify Different Skin Conditions and Improve Patient CareCompletedNCT07428954
• Efficacy and Safety of Fire Needle Therapy Combined With Cortex Phellodendri Compound Fluid Wet Compress for Acute Herpes Zoster: a Randomized Controlled Trial.CompletedNCT06985589Phase 4
• Rhomboid Intercostal and Subserratus Plane Block Versus Paravertebral Block for Thoracic Herpes ZosterCompletedNCT06751680Not applicable
• A Study of the Safety, Tolerability and Prelinminary Efficacy of BD111 in Herpes Simplex Virus Type I Stromal KeratitisActive, not recruitingNCT06474416Phase 1
• Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy VolunteersCompletedNCT06435507Phase 1
• Clinical Trial to Evaluate EuHZV in Healthy Adults Aged 50 to 69 YearsActive, not recruitingNCT06409494Phase 1
• Multidisciplinary Hospital-Territory Vaccine Center: a Model for Achieving the Herpes Zoster Vaccine CoverageCompletedNCT06334861
• Ultrasound-Guided Erectro Spinae Plane Block Versus Stellate Ganglion Block for Patients With Upper Limb Acute Herpes Zoster Pain.CompletedNCT06307444Not applicable
• Efficacy of Lazolex® Gel in the Treatment of Herpes SimplexCompletedNCT06089252Phase 2
• A First-in-Human Study to Evaluate JCXH-105, an SrRNA-based Herpes Zoster VaccineCompletedNCT05871541Phase 1
• A 48 Week Observational Study of the Frequency of Symptomatic Herpes Virus I and II in HIV Infected SubjectsStatus unknownNCT05823779
• Non-inferiority Study of ZK-A03 in Treatment of Herpes Zoster Before and After the Alteration of the Active Ingredient ManufacturerStatus unknownNCT05806918Phase 3
• A Clinical Study of Freshly Manufactured 35kDa Hyaluronan Fragment in the Treatment of PainCompletedNCT05756595Not applicable
• A Study to Evaluate Safety and Tolerability of a Recombinant Herpes Zoster VaccineStatus unknownNCT05750017Phase 1
• Phase I Clinical Trial of a Candidate Herpes Zoster VaccineStatus unknownNCT05718037Phase 1
• Trial Evaluating the Immunogenicity and Safety of an Adjuvanted Epstein-Barr Virus (EBV) Glycoprotein 350 Vaccine in EBV-seronegative PersonsCompletedNCT05683834Phase 1/2
• A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.Active, not recruitingNCT05683457Phase 2
• Knowledge of Young Adults About Genital HerpesStatus unknownNCT05675228
• A Study Exploring Efficacy of Peginterferon in Patients With Herpes ZosterCompletedNCT05492591Phase 2
• NPC-06 to Pain Associated With Acute Herpes ZosterCompletedNCT05480553Phase 3
• A Study on the Long-term Efficacy, Safety and Persistence of Immune Response of a Vaccine Against Herpes Zoster in Older AdultsActive, not recruitingNCT05371080Phase 3
• The Efficacy and Safety of Intradermal Acupuncture for Acute Herpes ZosterStatus unknownNCT05348382Not applicable
• A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital HerpesCompletedNCT05298254Phase 1/2
• Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult VolunteersCompletedNCT05245838Phase 1
• Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus InfectionCompletedNCT05226949
• Age Differences in Influenza and Herpes Zoster Vaccine Responses (INFLUENZA-SHINGRIX)CompletedNCT05082688Phase 2
• An Epidemiological Study to Assess Performance of Using Healthcare Tools to Understand Genital Herpes Simplex Virus-2 (HSV-2) in Patients ≥ 18 Years of Age in the United States and Europe.CompletedNCT04950712
• A Study on the Reactogenicity, Safety and Immune Response of a Vaccine Against Herpes Simplex Virus (HSV)-2 in Healthy Participants Aged 18-40 YearsTerminatedNCT04762511Phase 1
• Oral and Perioral Herpes Simplex Virus Infection Type I in a Five-month-old Infant: A Case ReportCompletedNCT04713423
• Study of the Efficacy and Safety of Combined Treatment of Patients With Severe Herpes Simplex (HSV) Infection by Valacyclovir and Interferon Inducer KagocelCompletedNCT04664127
• Erector Spinae Block Versus Thoracic Paravertebral Block for Acute Thoracic Herpes ZosterStatus unknownNCT04656821Phase 4
• Evaluating Adjunctive Cryopreserved Amniotic Membrane Treatment in Herpes Simplex Dendritic KeratitisWithdrawnNCT04598282Not applicable
• Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral KeratitisCompletedNCT04560790Not applicable
• Monoclonal Antibody Therapy Against Chronic Herpes Simplex Virus 1 InfectionTerminatedNCT04539483Phase 2
• HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade GliomaWithdrawnNCT04482933Phase 2
• NOWDx Test for the Diagnosis of Herpes Simplex Virus Type 2WithdrawnNCT04294030
• Occlusion vs Standard Treatment for the Treatment of Herpes ZosterStatus unknownNCT04258930Not applicable
• The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia AreataCompletedNCT04239521
• Study of 2LHERP® in Genital Herpes InfectionsTerminatedNCT04235322Phase 4
• Safety and Efficacy of 4 Investigational HSV 2 Vaccines in Adults With Recurrent Genital Herpes Caused by HSV 2TerminatedNCT04222985Phase 1
• Monoclonal Antibody Therapy Against Chronic Herpes Simplex Virus 2 InfectionCompletedNCT04165122Phase 2
• NPC-06 to Acute Pain in Herpes ZosterTerminatedNCT04139330Phase 2
• Pharmacokinetics of Valacyclovir Oral Solution in ChildrenTerminatedNCT04081480Not applicable
• Impact of Increased Immunoglobulin E to Anti-herpes Simplex Virus -1 Innate Immune Responses in Atopic Dermatitis Patients With Eczema HerpeticumStatus unknownNCT04060550
• Treatment of Herpes Labialis by Photodynamic TherapyCompletedNCT04037475Not applicable
• An Open Label Study to Evaluate the Safety and Efficacy of BOR15001L7 for the Treatment of Cold Sores in Patients With Recurrent Herpes LabialisStatus unknownNCT03977792Phase 2
• Herpes Zoster: Risk Factors, Complications and Special SituationsCompletedNCT03903237
• Melatonin Effects on Genital Herpes in Brazilian WomenCompletedNCT03831165Phase 4
• Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) KeratitisWithdrawnNCT03626376Phase 4
• Effectiveness and Clinical Mechanism of Huanglian-Jiedu Decoction in Patients With Intense-exuberant Stomach Fire SyndromeStatus unknownNCT03469232Phase 1/2
• Efficacy Trial of a Vaccine to Prevent Herpes Zoster in Adults Over 40 Years of AgeCompletedNCT03314103Phase 3
• Immune Evidence to the Consumption of Lactobacillus GG and FOS Consumption in Patients With Herpes LabialisCompletedNCT03310294Not applicable
• Immune Response to the Consumption of Lactobacillus GG and FOS in Patients With Recurrent Herpes LabialisCompletedNCT03307772Not applicable
• Femtosecond Laser-assisted Corneal Debridement for Herpes Simplex KeratitisStatus unknownNCT03217474Not applicable
• The Association Between Herpes Simplex Viruses and AutismStatus unknownNCT03180112
• Tzanck Smear With Methylene Blue Stain for HerpesStatus unknownNCT03178747Phase 3
• Effect of Early Use of Oxycodone During the Acute Phase of Herpes Zoster on Preventing Postherpetic NeuralgiaStatus unknownNCT03120962Not applicable
• MAMAS: Mentoring Adolescent Mothers at SchoolCompletedNCT03090802Not applicable
• Dexamethasone in Herpes Simplex Virus EncephalitisStatus unknownNCT03084783Phase 3
• Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised SubjectsCompletedNCT03073967Phase 3
• A Phase I-c Study of Recombinant GM-CSF Herpes Simplex Virus to TreatⅣ M1cStatus unknownNCT03048253
• Safety and Tolerability of Herpes Zoster Vaccine Rheumatologic PatientsStatus unknownNCT03016884Phase 4
• Observation on the Herpes Simplex KeratitisStatus unknownNCT03013959
• Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's DiseaseCompletedNCT02997982Phase 2
• Long-term Follow-up of GEN-003-002 Subjects for Efficacy and ImmunogenicityCompletedNCT02910284
• Study to Evaluate the Safety and Pharmacokinetics of Single Doses of ASP2151 in Healthy Male Subjects and the Effects of FoodCompletedNCT02852876Phase 1
• Safety and Efficacy Study of Herpes Simplex Virus Type 2 (HSV-2) Therapeutic DNA VaccineCompletedNCT02837575Phase 2
• Herpes Zoster Prevalence in Frailty ConsultationsCompletedNCT02832986
• A Retrospective Chart Review Study of Gene-Eden-VIR/NovirinCompletedNCT02715752
• Study to Evaluate the Safety and Pharmacokinetics of Topically Applied 40% Lidocaine Gel Compared With Placebo in Subjects With Acute Herpes Zoster (Shingles) PainTerminatedNCT02679339Phase 1
• Study of a New Topical Natural Health Product for the Treatment of Herpes LabialisStatus unknownNCT02582086Not applicable
• Safety Study of Monoclonal Antibodies to Reduce the Vaginal Transmission of HSV and HIVCompletedNCT02579083Phase 1
• HSV529 Vaccine in HSV-2 Seropositive AdultsCompletedNCT02571166Phase 1
• Evaluating New Formulation of Therapeutic HSV-2 VaccineCompletedNCT02515175Phase 2
• Safety, Tolerability and Therapeutic Efficacy of Topical ZEP-3 Ointment (1.0%) for the Treatment of Cold SoresCompletedNCT02483182Phase 2
• Review of Human Herpes Viruses in BurnsCompletedNCT02452229
• Antiviral Prophylaxis in a Burn PopulationWithdrawnNCT02349828Phase 2/3
• Study to Evaluate Safety, Tolerability, and Pharmacokinetics of UB-621 in Healthy VolunteersCompletedNCT02346760Phase 1
• Herpes Simplex Reactivation in Adult Critical Care PatientsStatus unknownNCT02322476
• Rollover Trial for Placebo Subjects Previously Enrolled Into GEN-003-002 StudyCompletedNCT02300142Phase 2
• Evaluation of the HSV 1 & 2 Assay in Specimens From Symptomatic SubjectsCompletedNCT02270099
• A Double-Blind, Randomized, Placebo-Controlled Study of Topical VDO for the Treatment of Herpes Simplex LabialisCompletedNCT02207881Phase 2
• Clinical Assessment of the Effectiveness and Safety of Herpes Patch SOS in the Treatment of Herpes Simplex Labialis in Comparison to a Competitor's Product.CompletedNCT02157090Not applicable
• A Study of Vacyless® Versus Valtrex® in Patients With Herpes ZosterCompletedNCT02152800Phase 4
• Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes ZosterCompletedNCT02151240Phase 4
• Comparison of a Live Herpes Zoster Vaccine and a Recombinant Vaccine in 50-59 and 70-85 Year OldsCompletedNCT02114333Phase 1
• Dose Ranging Safety and Efficacy of Therapeutic HSV-2 VaccineCompletedNCT02114060Phase 2
• The Flocked Swab and the Traditional Fiber Swab for the Diagnosis of the Herpes Simplex Epithelial KeratitisTerminatedNCT02045082Phase 4
• Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in AdultsCompletedNCT02030301Phase 1/2
• A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat CancerCompletedNCT01935453Phase 1
• A Study to Assess the Burden of Herpes Zoster and Postherpetic Neuralgia in Japanese Adults Aged Sixty Years and AboveCompletedNCT01873365
• Valacyclovir Augmentation for Cognitive and Functional Remediation in SchizophreniaCompletedNCT01794897Phase 4
• A Study to Investigate the Efficacy, Safety and Tolerability of PEG in Patients With Genital HerpesTerminatedNCT01765114Phase 2

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