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CompletedNCT03903237Updated Apr 4, 2019

Herpes Zoster: Risk Factors, Complications and Special Situations

An observational study in Herpes Zoster, sponsored by University Hospital, Basel, Switzerland. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-04-04.

Sponsored by University Hospital, Basel, Switzerland · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
355
Ages
18 Years and older
Sex
All
01

Study summary

This retrospective analysis is to investigate patients' history and clinical presentation in Herpes Zoster (HZ), Zoster-related complications, post-Zoster neuralgia and Herpes Zoster management in order to improve the management of HZ patients, to refine HZ-vaccination strategies and elucidate cost factors of HZ in in the setting of a university hospital in Switzerland generally and in a dermatology department specifically.

02

Conditions studied

  • Herpes Zoster

Keywords

  • post-zoster neuralgia
  • Herpes Zoster-related complications
03

In context

Herpes Simplex

305 studies on the registry are indexed under Herpes Simplex; 31 are open to participants now.

This study's enrollment of 355 is above the median of 180 across 55 observational studies indexed under Herpes Simplex.

Browse Herpes Simplex studies →

Lead sponsor

University Hospital, Basel, Switzerland is the lead sponsor of 968 studies on the registry; 191 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Probability sample

Study population

patients with HZ who were seen at University Hospital Basel between 2004-2018

Inclusion criteria

  • Reports of patients with HZ at University Hospital Basel between 2004-2018

Exclusion criteria

Exclusion Criteria:

  • rejection to use patient data
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
355 participants (actual)
Patient registry
No

Interventions

  • Otherretrospective chart review

    retrospective report review of HZ patients treated between 2005 and 2018 in the Department of Dermatology at the University Hospital Basel

06

What researchers measure

Primary outcomes

  1. Evaluation of patients' history

    Free text evaluation of patients' history (age, sex, comorbidities, immunosuppression, obesity, human immune deficiency Virus (HIV), profession, current medication, vaccinations, seasonal occurence of HZ, history of Varicella Zoster virus (VZV) infection

    Time frame: single time point assessment at baseline

  2. Description of the clinical presentation of HZ

    Free text description of the clinical presentation of HZ (localisation, dermatomes affected), Zoster-related acute pain

    Time frame: single time point assessment at baseline

  3. Evaluation of zoster-related complications

    Free text evaluation of zoster-related complications (ophthalmic zoster, generalised HZ, Ramsay-Hunt syndrome, zoster meningoencephalitis)

    Time frame: single time point assessment at baseline

  4. Evaluation of the herpes zoster management

    Free text evaluation of the herpes zoster management (local (antiviral) treatment, systemic antiviral and other treatments, number of revisits, average treatment-related costs, hospitalisations (rate, duration)

    Time frame: single time point assessment at baseline

  5. Assessment of post-zoster neuralgia

    Free text assessment of post-zoster neuralgia (annual incidence, treatment options used)

    Time frame: single time point assessment at baseline

  6. Evaluation of zoster and pregnancy

    Free text evaluation of zoster and pregnancy (incidence, time of pregnancy, pregnancy outcomes and complications)

    Time frame: single time point assessment at baseline

07

Study locations

1 site
  • Department of Dermatology, University Hospital Basel
    Basel, 4031, Switzerland
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 4, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT03903237
Lead sponsor
University Hospital, Basel, Switzerland
Responsible party
Sponsor
First posted
Apr 4, 2019
Start date
Dec 20, 2018
Primary completion
Feb 28, 2019
Completion
Feb 28, 2019
Last update
Apr 4, 2019

Study contacts

Simon Müller, Dr. med
principal investigator · Department of Dermatology, University Hospital Basel

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2019. You cannot join it, but the record below documents what was studied.

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