Hepatitis D clinical trials
The registry lists 63 studies for Hepatitis D across more than 10 countries. 21 are recruiting or about to start. 39 of them are mainly about Hepatitis D (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Hepatitis D, Chronic too: 95 studies, 28 open.
Get an email when these change. Save the Hepatitis D studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (7) · Vir Biotechnology, Inc. (4) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (4) · Mirum Pharmaceuticals, Inc. (4) · Eiger BioPharmaceuticals (3) · National Taiwan University Hospital (2) · HepNet Study House, German Liverfoundation (2) · University of Alabama at Birmingham (2)
What is being tested here
Drugs under test in Hepatitis D studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6, phase 3 first
- Dec 2026A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide · Phase 3 · Vir Biotechnology, Inc.
- Jun 2027A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2) · Phase 3 · Mirum Pharmaceuticals, Inc.
- Nov 2026A Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV Infection · Vir Biotechnology, Inc.
- Feb 2027Oral-Periodontal Evaluation and Assessment of Oral Fluid Biomarkers in Patients With Hepatitis B+D · Research Center of Periodontal-Systemic Interactions
- Sep 2027Community Screening and Management of Hepatitis B, C and Delta in the Mongolian Population Living in France · Hospices Civils de Lyon
- Sep 2027D-SOLVE Cohorts (Cohort A and B) · Hannover Medical School
Who these studies take
Of the 14 Hepatitis D studies recruiting now, 9 (64%) set no upper age limit and 1 (7%) stop at 75 or younger. 3 (21%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (7%) | 1 (7%) |
| 18 | 14 (100%) | 14 (100%) |
| 30 | 14 (100%) | 14 (100%) |
| 40 | 14 (100%) | 14 (100%) |
| 50 | 14 (100%) | 14 (100%) |
| 65 | 14 (100%) | 14 (100%) |
| 75 | 13 (93%) | 13 (93%) |
| 85 | 12 (86%) | 12 (86%) |
Across all 63 studies, recruiting or not: 25% stop at 75 or younger and 8% at 65; 17% take children; 0% are for women only and 0% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
- EXPANDED-ACCESS PROGRAM FOR THE TREATMENT OF CHRONIC HEPATITIS D WITH BRELOVITUGNov 6, 2026NCT07922733
Studies
Recruiting first, then most recently updated. Showing 50 of 63. Browse all 63 → or search them.
- Evaluation of Patients With Liver DiseaseRecruitingNCT000019711 country
- EXPANDED-ACCESS PROGRAM FOR THE TREATMENT OF CHRONIC HEPATITIS D WITH BRELOVITUGAvailableNCT079227331 country
- Effectiveness and Clinical Outcomes of Long-term Bulevirtide Monotherapy in Patients With HDV-related Compensated CirrhosisRecruitingNCT063978591 country
- Effectiveness and Safety of Bulevirtide (BLV) Therapy in Patients With Chronic Hepatitis Delta (CHD) in Italy (D-SHIELD)RecruitingNCT061222851 country
- "Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".RecruitingNCT046909721 country
- A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2)RecruitingNCT07200908Phase 312 countries
- D-SOLVE Cohorts (Cohort A and B)RecruitingNCT061606354 countries
- A Phase III Study to Evaluate the Efficacy and Safety of Libevitug in Participants With Chronic HDV Infection (D-clear Study)RecruitingNCT07499544Phase 33 countries
- Hepatitis B Infection SurveillanceNot yet recruitingNCT077271871 country
- "Referral Attivo" Delta, Dallo Screening Alla Presa in Carico.RecruitingNCT073170111 country
- Oral-Periodontal Evaluation and Assessment of Oral Fluid Biomarkers in Patients With Hepatitis B+DRecruitingNCT074918481 country
- Community Screening and Management of Hepatitis B, C and Delta in the Mongolian Population Living in FranceNot yet recruitingNCT07038863Not applicable1 country
- DELTA DESCRIBE: the French Collaborative ProjectRecruitingNCT059360731 country
- HDV Screening StudyRecruitingNCT068898051 country
- MIGrant Reflex Test HDV (MIGRED) ProjectNot yet recruitingNCT06539052
- Determination of New Detection and Quantification Thresholds for Serological and Molecular Tests for Hepatitis Delta Virus (HDV) Using Capillary Blood on Blotting Paper (DBS)Not yet recruitingNCT06649396Not applicable1 country
- HDV-Europe: Prevalence and Outcome of HDV in HIV/HBV CoinfectionRecruitingNCT062645831 country
- Standardising Care for Hepatitis Delta in the NetherlandsRecruitingNCT059037421 country
- HEllenic Multicenter ReAl-life CLInical Study for Bulevirtide Therapy in Chronic Hepatitis D: HERACLIS-BLVRecruitingNCT059280001 country
- A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-InfectionNot yet recruitingNCT05467553Phase 21 country
- Registry-based Study in Patients With Hepatitis D Virus (HDV) Infection in ChinaNot yet recruitingNCT054510821 country
- Immunological and Virological Characterization of Patients With Chronic HBV-HDV Infection: Outcomes and Response to Bulevirtide TreatmentCompletedNCT065044851 country
- A Study to Evaluate Tobevibart + Elebsiran in Chronic HDV InfectionActive, not recruitingNCT06903338Phase 310 countries
- A Clinical Trial of Hepalatide for Injection in Patients With Chronic Hepatitis DCompletedNCT06505928Phase 21 country
- A Trial Evaluating BJT-778 vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta InfectionActive, not recruitingNCT06907290Phase 2/311 countries
- A Study to Assess Efficacy and Safety of HH-003 Injection in Subjects With Chronic Hepatitis Delta Virus InfectionCompletedNCT05861674Phase 22 countries
- A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With BulevirtideActive, not recruitingNCT07128550Phase 37 countries
- Liver Fibrosis in Zambian HIV-HBV Co-infected PatientsCompletedNCT023446801 country
- A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)Active, not recruitingNCT07298330Phase 310 countries
- SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.Active, not recruitingNCT05461170Phase 29 countries
- Expanded Access for BulevirtideApproved for marketingNCT06780579
- Chronic Hepatitis B Virus Infection in ZambiaCompletedNCT031588181 country
- Once Daily Dosing of Lonafarnib Co-administered With Ritonavir for Treatment of Chronic Hepatitis D Virus InfectionCompletedNCT05229991Phase 33 countries
- A Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV InfectionActive, not recruitingNCT07142811Phase 211 countries
- Study of ARC-520 With or Without Other Drugs Used in the Treatment of Chronic Chronic Hepatitis B Virus (HBV)TerminatedNCT02577029Phase 28 countries
- A Study to Assess the Safety, Tolerability and Pharmacokinetics of ABI-6250 in Healthy ParticipantsCompletedNCT06740474Phase 11 country
- Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)Active, not recruitingNCT048637031 country
- Replicor Compassionate Access ProgramNo longer availableNCT056835485 countries
- Peginterferon Lambda and Lonafarnib Boosted With Ritonavir 48-Week Combination Therapy for Delta HepatitisWithdrawnNCT05953545Phase 21 country
- Prevalence and Clinical Characterization of Hepatitis D Virus (HDV) Infection Among Sudanese Patients With Hepatitis B VirusCompletedNCT063604841 country
- Patient Knowledge, Beliefs and Barriers to Hepatitis D CareStatus unknownNCT06017375
- Phase 3 Study to Evaluate the Efficacy and Safety of Peginterferon Lambda for 48 Weeks in Patients With Chronic HDVActive, not recruitingNCT05070364Phase 312 countries
- Efficacy and Safety of Bulevirtide (BLV) Therapy in HDV Chronic Hepatitis (CHD) in ItalyCompletedNCT059623071 country
- Epidemiology of Hepatitis B, C and D and HIV Along the Maroni River Bordering French Guiana and Suriname (MaHeVi)CompletedNCT050029072 countries
- Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2aCompletedNCT03719313Phase 322 countries
- A Study of Safety and Efficacy of ATI-2173 in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection and in Subjects With Hepatitis D Virus CoinfectionTerminatedNCT04847440Phase 22 countries
- Prevalence and Burden of Hepatitis D Virus Infection in China Through Preoperative Examination Test (Predict Study)Status unknownNCT05394623
- The Hepatitis Delta International NetworkCompletedNCT0237590612 countries
- Disease Loads and Status of TreatmentStatus unknownNCT052642721 country
- Treatment of Chronic Delta Hepatitis With Lonafarnib, Ritonavir and Lambda InterferonCompletedNCT03600714Phase 21 country