Gliosarcoma clinical trials
The registry lists 488 studies for Gliosarcoma across more than 10 countries. 14 are recruiting or about to start. 17 of them are mainly about Gliosarcoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
National Cancer Institute (NCI) (95) · Duke University (37) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (34) · M.D. Anderson Cancer Center (22) · Jonsson Comprehensive Cancer Center (15) · European Organisation for Research and Treatment of Cancer - EORTC (13) · City of Hope Medical Center (11) · Memorial Sloan Kettering Cancer Center (10)
What is being tested here
Drugs under test in Gliosarcoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Alkylating agents 2 open · Tyrosine kinase inhibitors (TKIs) 2 open · Immune checkpoint inhibitors 2 open · HDAC inhibitors 1 open · Angiogenesis inhibitors 35
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Jan 2027Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain Tissue · Baptist Health South Florida
- Jan 2027A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma · James Markert, MD
- Jan 2027A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. · University College, London
- Jan 2027Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM · M.D. Anderson Cancer Center
- Feb 2027Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma · National Cancer Institute (NCI)
- Mar 2027A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas · Julie Krystal
- Mar 2027Study of Pembrolizumab and M032 (NSC 733972) · University of Alabama at Birmingham
- Mar 2027Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms · Jazz Pharmaceuticals
- Jun 2027Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas · Cellectar Biosciences, Inc.
- Jul 2027A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Glioma · University of Nebraska
Who these studies take
Of the 12 Gliosarcoma studies recruiting now, 11 (92%) set no upper age limit and 1 (8%) stop at 75 or younger. 2 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (8%) | 1 (8%) |
| 18 | 11 (92%) | 11 (92%) |
| 30 | 11 (92%) | 11 (92%) |
| 40 | 11 (92%) | 11 (92%) |
| 50 | 11 (92%) | 11 (92%) |
| 65 | 11 (92%) | 11 (92%) |
| 75 | 11 (92%) | 11 (92%) |
| 85 | 11 (92%) | 11 (92%) |
Across all 488 studies, recruiting or not: 9% stop at 75 or younger and 6% at 65; 9% take children; 0% are for women only and 1% for men only; <1% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Gliosarcoma studies take
Of 54 phase 1 interventional studies under Gliosarcoma, half reached primary completion within 59 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 59 mo36–106 · 54 studies | — | 53 mo35–90 · 48 studies |
| Phase 1/2 | 68 mo53–82 · 24 studies | — | — |
| Phase 2 | 49 mo32–69 · 43 studies | — | 49 mo32–71 · 42 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 488. Browse all 488 → or search them.
- GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 AstrocytomaRecruitingNCT07301268Phase 21 country
- Metronomic Temozolomide With Dexbrompheniramine for Recurrent High-Grade Glioma/GlioblastomaNot yet recruitingNCT07859059Phase 1/21 country
- MSC-DNX-2401 in Treating Patients With Recurrent High-Grade GliomaRecruitingNCT03896568Phase 11 country
- ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG TrialRecruitingNCT07089641Phase 11 country
- A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent GliomaRecruitingNCT05698524Phase 11 country
- Study of ABBV-637 or ABBV-155 With ERAS-801 for People With GlioblastomaRecruitingNCT06934889Phase 11 country
- Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBMRecruitingNCT04991870Phase 11 country
- HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 11 country
- Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational StudyRecruitingNCT069546361 country
- Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent GlioblastomaNot yet recruitingNCT07422363Phase 1
- A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment.RecruitingNCT07134842Phase 11 country
- Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain TissueRecruitingNCT057569851 country
- Study of Pembrolizumab and M032 (NSC 733972)RecruitingNCT05084430Phase 1/21 country
- Intracavitary Photodynamic Therapy as an Adjuvant to Resection of Glioblastoma or Gliosarcoma Using IV Photobac®RecruitingNCT05363826Phase 11 country
- Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated GlioblastomaCompletedNCT04396860Phase 2/31 country
- Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsActive, not recruitingNCT04541082Phase 11 country
- Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant GliomaCompletedNCT02062827Phase 11 country
- Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade GliomasCompletedNCT02015819Phase 11 country
- Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma MultiformeActive, not recruitingNCT02152982Phase 2/32 countries
- Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed GlioblastomaCompletedNCT04216329Phase 11 country
- Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent GlioblastomaActive, not recruitingNCT04528680Phase 1/21 country
- SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed GlioblastomaActive, not recruitingNCT02455557Phase 21 country
- Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2CompletedNCT01082926Phase 11 country
- Phase I Trial of DNA-PK Inhibitor (PEPOSERTIB ) in Combination With Radiation and Adjuvant Temozolomide in Newly Diagnosed MGMT Unmethylated and Recurrent GlioblastomaActive, not recruitingNCT04555577Phase 11 country
- Efineptakin Alfa and Pembrolizumab for the Treatment of Recurrent GlioblastomaActive, not recruitingNCT05465954Phase 21 country
- Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and SarcomasActive, not recruitingNCT03478462Phase 13 countries
- Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant GliomaCompletedNCT00730613Phase 1
- Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed GlioblastomaActive, not recruitingNCT05864534Phase 21 country
- Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT03174197Phase 1/21 country
- Pembrolizumab and Standard Therapy in Treating Patients With GlioblastomaActive, not recruitingNCT03197506Phase 21 country
- DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent GlioblastomaActive, not recruitingNCT03115333Not applicable1 country
- Pembrolizumab in Treating Patients With Recurrent GlioblastomaActive, not recruitingNCT02337686Phase 21 country
- Atezolizumab and Cabozantinib for the Treatment of Recurrent GlioblastomaActive, not recruitingNCT05039281Phase 1/21 country
- Vorinostat and Temozolomide in Treating Patients With Malignant GliomasActive, not recruitingNCT00268385Phase 11 country
- Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated GlioblastomaActive, not recruitingNCT05095376Phase 32 countries
- A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant GliomaActive, not recruitingNCT06614855Phase 11 country
- A Phase I Study of Mebendazole for the Treatment of Pediatric GliomasActive, not recruitingNCT01837862Phase 1/21 country
- Phase I Pilot Study to Evaluate the Anti-glioblastoma Effect of S-Gboxin in Standard Treatment of Glioblastoma/Diffuse Midline Glioma and Response to Treatment (Regardless of Mutation Status)SuspendedNCT06806228Phase 13 countries
- Mycophenolate Mofetil Combined With Radiation Therapy in GlioblastomaActive, not recruitingNCT04477200Phase 11 country
- Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade GliomasActive, not recruitingNCT02192359Phase 11 country
- Natural Progesterone for the Treatment of Recurrent GlioblastomaTerminatedNCT05091866Early Phase 11 country
- Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or GliosarcomaCompletedNCT04817254Phase 21 country
- Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and GlioblastomaTerminatedNCT02942264Phase 1/21 country
- Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent GlioblastomaCompletedNCT02709226Phase 11 country
- Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With GlioblastomaCompletedNCT03746080Phase 21 country
- Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain CancerTerminatedNCT03107780Phase 11 country
- Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant GliomaCompletedNCT01165632Early Phase 11 country
- Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior BevacizumabCompletedNCT01931098Phase 21 country
- Spectroscopic MRI-Guided Radiation Therapy Planning in GlioblastomaCompletedNCT03137888Phase 21 country
- Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated GlioblastomaCompletedNCT03452930Phase 11 country