Genetic Predisposition to Disease clinical trials
The registry lists 241 studies for Genetic Predisposition to Disease across more than 10 countries. 95 are recruiting or about to start. 79 of them are mainly about Genetic Predisposition to Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its narrower condition Genetic Risk Score too: 286 studies, 124 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
University Hospital Tuebingen (10) · National Institute of Environmental Health Sciences (NIEHS) (7) · Brigham and Women's Hospital (6) · Abramson Cancer Center at Penn Medicine (6) · St. Jude Children's Research Hospital (6) · The University of Hong Kong (5) · Mayo Clinic (5) · National Cancer Institute (NCI) (4)
What is being tested here
Drugs under test in Genetic Predisposition to Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026The China Neonatal Genomes Project · Children's Hospital of Fudan University
- Dec 2026VIGOR: Virtual Genome Center for Infant Health · Boston Children's Hospital
- Dec 2026Microbiome and Association With Implant Infections · University of California, San Francisco
- Dec 2026Understanding Gene ENvironment Interaction in ALcohol-related Hepatocellular Carcinoma · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
- Jan 2027Exploring the Genetics of Neuropathic Pain · Oslo University Hospital
- Jan 2027Healthy Volunteers Study · Abramson Cancer Center at Penn Medicine
- Jan 2027Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM Study · Dana-Farber Cancer Institute
- Mar 2027Investigating the Role of Genetics in Disease Predisposition · The Wellcome Sanger Institute
- Mar 2027Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery · Institut de Recerca Biomèdica de Lleida
- Mar 2027Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) · NHS Greater Glasgow and Clyde
Who these studies take
Of the 71 Genetic Predisposition to Disease studies recruiting now, 36 (51%) set no upper age limit and 28 (39%) stop at 75 or younger. 25 (35%) take children under 18. 9 (13%) are for women only and 5 (7%) for men only; 23 (32%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 24 (34%) | 22 (31%) |
| 18 | 50 (70%) | 47 (66%) |
| 30 | 49 (69%) | 45 (63%) |
| 40 | 48 (68%) | 46 (65%) |
| 50 | 52 (73%) | 49 (69%) |
| 65 | 51 (72%) | 48 (68%) |
| 75 | 42 (59%) | 40 (56%) |
| 85 | 39 (55%) | 37 (52%) |
Across all 241 studies, recruiting or not: 36% stop at 75 or younger and 24% at 65; 30% take children; 11% are for women only and 6% for men only; 41% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Genetic Predisposition to Disease studies take
Of 82 observational studies under Genetic Predisposition to Disease, half reached primary completion within 96 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 36 mo18–128 · 57 studies | — | 36 mo18–128 · 57 studies |
| Observational | 96 mo52–… · 82 studies | — | 96 mo52–… · 80 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 241. Browse all 241 → or search them.
- Helix Research NetworkRecruitingNCT060571811 country
- Prostate Cancer Genetic Risk Evaluation and Screening StudyRecruitingNCT051296051 country
- The Preventive Risk Outreach And Cascade TestingNot yet recruitingNCT07478237Not applicable
- Vascular Disease Discovery ProtocolRecruitingNCT035386391 country
- Mayo Clinic Tapestry 2.0: Applying Multi-Omics for Scientific DiscoveryEnrolling by invitationNCT064563201 country
- Breast Cancer Risk Assessment and Management ProgramEnrolling by invitationNCT07911592Not applicable1 country
- Pancreatic Cancer Early Detection ConsortiumRecruitingNCT0497005612 countries
- Precision-Based Genomics in Prostate CancerRecruitingNCT047066631 country
- Slow-SPEED: Slowing Parkinson's Early Through Exercise DosageRecruitingNCT06993142Not applicable2 countries
- Effects of Sirolimus on Asymptomatic ApoE4 CarriersRecruitingNCT07728175Phase 11 country
- COsegregation of VARiants in Panel of GenesRecruitingNCT01689584Not applicable5 countries
- Investigating Hereditary Risk In Thoracic Cancers (INHERIT)RecruitingNCT055874391 country
- Precure Targeted Accrual and Rapid Growth in Enrollment Trial StudyEnrolling by invitationNCT077563201 country
- Using the EHR to Advance Genomic Medicine Across a Diverse Health SystemRecruitingNCT06377033Not applicable1 country
- Measuring Athlete's Risk of Cardiovascular Events 3 (MARC-3)Enrolling by invitationNCT076254881 country
- Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology PatientsRecruitingNCT025306581 country
- Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast ReconRecruitingNCT07264790Phase 11 country
- GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGHRecruitingNCT06003153Phase 41 country
- Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral PalsyRecruitingNCT06554288Phase 11 country
- Outcomes of Health Care Transition for AYA With a Cancer PredispositionRecruitingNCT074569041 country
- Familial Investigations of Childhood Cancer PredispositionRecruitingNCT030502681 country
- Bundled Cancer Screening and Genetic Services NavigationRecruitingNCT07228000Not applicable1 country
- Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor SyndromesRecruitingNCT047318571 country
- Germline Testing for Predisposition to Myeloid MalignanciesRecruitingNCT07112287Not applicable1 country
- Barriers and Facilitators of Parent-Child Communication in Children With Cancer PredispositionRecruitingNCT058491551 country
- Study of a Polygenic Risk Score to Predict the Risk of Pancreatic Ductal AdenocarcinomaNot yet recruitingNCT07516392Not applicable
- EXOME Analysis Position in the Strategy of Genetic Predisposition Factors Identification in Early-onset CancerRecruitingNCT04141462Not applicable1 country
- Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary SyndromeRecruitingNCT064419421 country
- Genetic Susceptibility to Periprosthetic Joint InfectionsEnrolling by invitationNCT051597391 country
- Microbiome and Association With Implant InfectionsRecruitingNCT05020574Phase 21 country
- The China Neonatal Genomes ProjectRecruitingNCT039317071 country
- Mayo Clinic Precure - Prospective StudyEnrolling by invitationNCT073325981 country
- Assesment of Multiomics Profiles in Health and Disease.RecruitingNCT044271631 country
- Healthy Volunteers StudyRecruitingNCT069620591 country
- The i4i PRODICT® Study: Evaluation of the i4i PRODICT® Test in Different Ethnic Groups (The i4i PRODICT® Study).RecruitingNCT066365261 country
- Genetic Predisposition to High Blood PressureEnrolling by invitationNCT07181213Not applicable1 country
- Blood Markers of Early Pancreas CancerRecruitingNCT035686301 country
- The Effect of rs7903146 Genotype on Islet GLP-1 Production in HumansNot yet recruitingNCT06972407Phase 21 country
- Key Longitudinal Associations With Risk and Glioblastoma OutcomesRecruitingNCT066256841 country
- Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Population: The INFORM StudyRecruitingNCT06450171Not applicable1 country
- Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic LeukemiaRecruitingNCT055121691 country
- Genetic Investigation of Cancer PredispositionNot yet recruitingNCT046202781 country
- Precision Medicine in the Prostate Cancer Care PathwayRecruitingNCT047633171 country
- Understanding Gene ENvironment Interaction in ALcohol-related Hepatocellular CarcinomaRecruitingNCT07272200Not applicable1 country
- PTX3-targeted Antifungal ProphylaxisRecruitingNCT03828773Not applicable3 countries
- Evaluation of Risk of hEpatocellular CarcinomaRecruitingNCT06523179Not applicable1 country
- Prostate Tissue BioBankRecruitingNCT066596141 country
- Genetic Information Assistant in TelegeneticsRecruitingNCT06089421Not applicable1 country
- Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DMRecruitingNCT06256419Not applicable1 country
- InterNatIonal CHildhood Leukemia Microbiome/MEtabolome CohortRecruitingNCT059299766 countries