Drug
Posaconazole clinical trials
Also written Noxafil, MK-5592 and SCH 056592.
- studies test it
- 52
- open now
- 6
- in phase 3
- 13
- first study started
- 1998
Keep track of what changes. Save the posaconazole studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
52 studies that test it; most in 2017 (6)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 1999 | 1 |
| 2001 | 2 |
| 2002 | 2 |
| 2004 | 1 |
| 2007 | 4 |
| 2008 | 4 |
| 2009 | 4 |
| 2010 | 2 |
| 2011 | 1 |
| 2013 | 5 |
| 2014 | 1 |
| 2015 | 3 |
| 2016 | 1 |
| 2017 | 6 |
| 2018 | 3 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 4 |
| 2024 | 2 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 11
- Phase 2
- 15
- Phase 3
- 13
- Phase 4
- 10
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
- Mycoses
- 10
Who runs them
Industry 27 · Other 25
Merck Sharp & Dohme LLC (22) · Radboud University Medical Center (4) · M.D. Anderson Cancer Center (2) · Hoffmann-La Roche (2) · F2G Biotech GmbH (2) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Seoul National University Hospital (1) · Children's Mercy Hospital Kansas City (1)
Often tested with
Tested in the same studies.
Fluconazole (2) · Olorofim (2) · Fosamprenavir (1) · Milademetan (1) · Benzonidazole (1) · Micafungin (1) · Alectinib (1) · Amphotericin B (1)
Studies
Open first, then newest update. How each study uses posaconazole is read from its arms, and is right about nine times in ten.
Testing it · 52
- Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)Not yet recruitingPhase 3University of MinnesotaNCT07261150Written as Posaconazole
- Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)RecruitingPhase 2Merck Sharp & Dohme LLCNCT04665037Written as Posaconazole IV 6 mg/kg
- Posaconazole Plus PD-1 Inhibitors and Chemotherapy vs PD-1 Inhibitors and Chemotherapy in Neoadjuvant Therapy for Triple Negative Breast CancerRecruitingPhase 2Shandong Cancer Hospital and InstituteNCT06802757Written as Posaconazole
- Study of Posaconazole Prophylaxis in Patients Receiving Hematopoietic Stem Cell Allograft (Allo-HSC) at High Risk of Invasive Fungal Infection (IFI)RecruitingPhase 2Nantes University HospitalNCT06541067Written as Posaconazole
- PTX3-targeted Antifungal ProphylaxisRecruitingNot applicableBochud Pierre-YvesNCT03828773Written as Posaconazole
- Azoles Targeting Recurrent High Grade GliomasNot yet recruitingEarly Phase 1University Health Network, TorontoNCT03763396Written as Posaconazole (PCZ)
- Amphotericin Versus Posaconazole for Pulmonary MucormycosisCompletedPhase 2Post Graduate Institute of Medical Education and Research, ChandigarhNCT05468372Written as Posaconazole 600 mg followed by posaconazole 300 mg once daily
- Pilot Study of Posaconazole in Crohn's DiseaseTerminatedPhase 4Cedars-Sinai Medical CenterNCT04966585Written as Posaconazole Delayed Release Oral Tablet
- Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical TrialTerminatedEarly Phase 1Milton S. Hershey Medical CenterNCT04825275Written as Posaconazole Pill
- Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)CompletedPhase 2Merck Sharp & Dohme LLCNCT04218851Written as Posaconazole IV
- Posaconazole Prophylaxis During ATG Treatment for hMDS/AA PatientsCompletedPhase 2Seoul National University HospitalNCT03318159Written as Posaconazole
- A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)CompletedPhase 3Merck Sharp & Dohme LLCNCT01782131Written as Posaconazole
- Pharmacokinetics Variability of Posaconazole (PCZ) and Its Glucuronide Metabolite During Induction and Consolidation Treatments in Patients With Acute Myeloid Leukemia (AML): a Covariate Analysis With the Tablets Formulation and Evaluation of the Potential Risk of HepatotoxicityStatus unknownNot applicableHospices Civils de LyonNCT03796533Written as Posaconazole
- A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus InfectionStatus unknownPhase 2/3Bambino Gesù Hospital and Research InstituteNCT04966234Written as Posaconazole 100 MG [Noxafil]
- Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)CompletedPhase 3Merck Sharp & Dohme LLCNCT02180165Written as Posaconazole
- Genetic Variation and Variability in Posaconazole Pharmacokinetics in ChildrenCompletedPhase 1Children's Mercy Hospital Kansas CityNCT02358499Written as Posaconazole
- Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD)CompletedPhase 2Radboud University Medical CenterNCT00799071Written as posaconazole (PSZ)
- Pharmacokinetic Study of Posaconazole Boosted FosamprenavirCompletedPhase 1Radboud University Medical CenterNCT00817765Written as Posaconazole
- Dosing Obese With Noxafil® Under a Trial (DONUT)CompletedPhase 4Radboud University Medical CenterNCT03246386Written as Posaconazole Injection [Noxafil] 300mg
- King's Invasive Aspergillosis Study IICompletedPhase 4King's College Hospital NHS TrustNCT02875743Written as Posaconazole
See all 52 studies that test posaconazole →
Given in every arm · 9 — posaconazole is usual care beside what is tested
- Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX OverexpressionRecruitingPhase 1/2AstraZenecaNCT07155226Written as Posaconazole
- Phase 1 Open-label Study of AMX-883 Alone in Participants With AML and High-risk MDS and in Combination in Participants With AMLRecruitingPhase 1Amphista Therapeutics LtdNCT07723703Written as Posaconazole
- A Study of BGB-11417 in Participants With Myeloid MalignanciesRecruitingPhase 1/2BeOne MedicinesNCT04771130Written as Posaconazole
- Study of Monzosertib In Patients With R/R AML Or High-Risk Myelodysplastic SyndromeNot yet recruitingPhase 1M.D. Anderson Cancer CenterNCT07780565Written as Posaconazole
- A Study to Evaluate S241656 Alone or in Combination in Participants With Selected Myeloid MalignanciesNot yet recruitingPhase 1/2ServierNCT07719348Written as Posaconazole
- Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host DiseaseCompletedPhase 2National Cancer Institute (NCI)NCT04294641Written as Posaconazole
- Study of ABT-199 (GDC-0199) in Combination With Azacitidine or Decitabine (Chemo Combo) in Subjects With Acute Myelogenous Leukemia (AML)TerminatedPhase 1AbbVieNCT02203773Written as Posaconazole
- HDM201 Added to CT in R/R or Newly Diagnosed AMLWithdrawnPhase 1/2Novartis PharmaceuticalsNCT03760445Written as posaconazole
- Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for Invasive Fungal Infections (P05520)CompletedPhase 1Merck Sharp & Dohme LLCNCT01075984Written as Posaconazole
As the comparator · 2 — what is tested is compared with posaconazole
- Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow TransplantationCompletedPhase 3Mundipharma Research LimitedNCT04368559Written as Posaconazole
- Posaconazole for the Prevention of Influenza-associated Aspergillosis in Critically Ill PatientsCompletedPhase 4Universitaire Ziekenhuizen KU LeuvenNCT03378479Written as SOC +Posaconazole 18 MG/ML (milligram/milliliter)
Codes
What other systems call posaconazole · ClinicalTrials.gg INT003932
- MeSH (NLM) C101425posaconazoleConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6TK1G07BHZPOSACONAZOLEConfirmed FDA, NLM, Wikidata
- RxNorm 282446Confirmed FDA, Wikidata
- Wikidata Q906453posaconazoleConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61500PosaconazoleConfirmed FDA, Wikidata
- DrugBank DB01263One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C101425 | posaconazole | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6TK1G07BHZ | POSACONAZOLE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 282446 | — | Confirmed FDA, Wikidata |
| Wikidata | Q906453 | posaconazole | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61500 | Posaconazole | Confirmed FDA, Wikidata |
| DrugBank | DB01263 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.