Exocrine Pancreatic Insufficiency: all 129 studies

Page 1 of 2. Open to participants first (26), then studies with results posted, then the rest; newest registration first within each.

• A Study on the Efficacy of Different Doses of Oryz-Aspergillus Enzyme And Pancreatin Tablet in Treating Pancreatic Exocrine Insufficiency After Gastrointestinal SurgeryNot yet recruitingNCT07751367Not applicable
• A Multicenter Clinical Study on Protein Absorption Efficiency in Patients With Pancreatic Exocrine Insufficiency in the ICUNot yet recruitingNCT07709611Phase 4
• Comparative Study to Evaluate Microbial Versus Porcine Pancreatic Enzyme Therapy in Chronic PancreatitisRecruitingNCT07697352Phase 3
• A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.RecruitingNCT07559175Phase 2
• Nutrition Intervention for Pancreatic CancerRecruitingNCT07554560Not applicable
• IPEX Study: Pancreatic Exocrine Insufficiency as a Functional Marker of Disease Progression in Patients With IPMNNot yet recruitingNCT07535125
• Assessment of Pancreatic Dysfunction in Patients With Type 2 DiabetesRecruitingNCT07512934
• Breath Test-Based Assessment of SIBO in Chronic Pancreatitis and Partial PancreatectomyNot yet recruitingNCT07479238
• Phase 2 Study to Assess the Safety and Efficacy of ANG003RecruitingNCT07450547Phase 2
• Pancreatic Enzyme Replacement in Acute Necrotizing PancreatitisRecruitingNCT07441824Phase 3
• Malabsorption Blood Test (MBT) to Determine Exocrine Pancreatic Function and Related Quality of Life in Chronic PancreatitisRecruitingNCT07418593Phase 4
• Determine the Prevalence of Exocrine Pancreatic Insufficiency (EPI) in Pediatric and Adult Participants With Alagille Syndrome After Liver TransplantationRecruitingNCT07335523
• PERT in Acute Necrotizing PancreatitisNot yet recruitingNCT07211568Phase 3
• Shwachman-Diamond Syndrome Global Patient Survey and Partnering PlatformRecruitingNCT06999954
• Dorzagliatin in Pancreatic Insufficient Cystic FibrosisRecruitingNCT06995651Phase 1
• Fatty Liver and Pancreatic SteatosisNot yet recruitingNCT06757348
• Exocrine Pancreatic Insufficiency and Functional DyspepsiaNot yet recruitingNCT06756503
• Evaluating the Efficacy of RELiZORB in Managing Exocrine Pancreatic Insufficiency in Tube-fed Pancreatitis PatientsRecruitingNCT06691893Phase 3
• Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic InsufficiencyRecruitingNCT06477159Phase 4
• The Effect of PERT on Patients Undergoing PancreaticoduodenectomyRecruitingNCT06119880Phase 4
• Establishment and Clinical Application of Pancreatic Endocrine and Exocrine Function TestsRecruitingNCT06006312
• The Development of a Metabolomic Test to Diagnose and Quantify Pancreatic Exocrine Insufficiency (The DETECTION Study)RecruitingNCT05980221Not applicable
• The Effects of Pancreatic Enzyme Supplementation in Critically Ill Patients on Enteral FeedingRecruitingNCT05112328Not applicable
• GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose IntoleranceRecruitingNCT04731272Phase 2
• Investigating Predictive Factors of Diabetes Occurence After DuodenalpancreatectomyRecruitingNCT02175459
• Beta-cell Response to Incretin Hormones in Cystic FibrosisRecruitingNCT01851694Not applicable
• Phase 1 Study to Assess Safety and Efficacy of ANG003CompletedNCT06052293Phase 1Results posted
• Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic FibrosisCompletedNCT05719311Phase 2Results posted
• Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fibrosis or Chronic Pancreatitis Treated With CreonCompletedNCT05069597Phase 4Results posted
• OPTION 2: A Trial to Assess the Safety and Efficacy of MS1819 in Enteric Capsules in Patients With Cystic FibrosisCompletedNCT04375878Phase 2Results posted
• A Study to Compare US Marketed Creon Manufactured With a Modernized Process at an Alternate Manufacturing Site and Manufactured With the Approved Manufacturing Process at an Alternate Active Pharmaceutical Ingredient Site, in Participants With Exocrine Pancreatic Insufficiency Due to Cystic FibrosisCompletedNCT03924947Phase 4Results posted
• A Study of Creon (Pancrelipase) in Resected and Non-resected Pancreatic Cancer Participants With Exocrine Pancreatic Insufficiency (EPI)TerminatedNCT03859869Phase 4Results posted
• OPTION: A Trial to Assess the Safety & Efficacy of MS1819 in Patients With Exocrine Pancreatic Insufficiency Due to Cystic FibrosisCompletedNCT03746483Phase 2Results posted
• Proton Pump Inhibitors (PPI) and Fat Absorption in Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (EPI)CompletedNCT03551691Phase 2Results posted
• PERT for Treatment of Exocrine Pancreatic Insufficiency in Patients With Unresectable Pancreatic CancerTerminatedNCT02985801Phase 1/2Results posted
• EASY: Extended Access to Sollpura Over YearsCompletedNCT02823964Phase 4Results posted
• SIMPLICITY: Studying Impacts on Malabsorption With Liprotamase in Cystic FibrosisCompletedNCT02734810Phase 3Results posted
• Safety, Tolerability and Fat Absorption Using Enteral Feeding In-line Enzyme Cartridge (Relizorb)CompletedNCT02598128Not applicableResults posted
• Efficacy and Safety Study of Creon IR in Subjects With Pancreatic Exocrine Insufficiency Due to Cystic FibrosisCompletedNCT02415959Phase 2Results posted
• A Study to Investigate How Common Pancreatic Exocrine Insufficiency (PEI) is in Patients With Type 2 Diabetes and Also to Investigate the Uptake of a Single Dose of EPANOVA® or OMACOR® in Patients With Different Degrees of PEICompletedNCT02370537Phase 2Results posted
• SOLUTION: Study of Oral Liprotamase Unit-Matched Therapy Of Non-Porcine Origin in Patients With Cystic FibrosisCompletedNCT02279498Phase 3Results posted
• A Double-blind, Randomized, Multicenter, Cross-over Study to Compare the Effect of Creon N and Creon® on Fat Digestion in Subjects ≥ 12 Years of Age With Pancreatic Exocrine Insufficiency Due to Cystic FibrosisCompletedNCT02137382Phase 3Results posted
• Effect of Chronic Incretin-based Therapy in Cystic FibrosisCompletedNCT01879228Not applicableResults posted
• Evaluation of Safety and Tolerability of Creon Micro in Children Younger Than Four Years With Pancreatic Exocrine InsufficiencyCompletedNCT01747330Phase 3Results posted
• Special Investigation of LipaCreon on Long-term Use in Patients With Pancreatic Exocrine InsufficiencyCompletedNCT01427725Results posted
• Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic FibrosisCompletedNCT01427712Results posted
• Control of Steatorrhea in Participants With Cystic Fibrosis and Exocrine Pancreatic InsufficiencyCompletedNCT01327703Phase 4Results posted
• PR-018: An Open-Label, Safety Extension of Study PR-011CompletedNCT01131507Phase 4Results posted
• A Study to Evaluate the Mode of Administration and Safety of EUR-1008 (APT-1008) in Infants 1 to 12 Months of AgeCompletedNCT01100606Phase 4Results posted
• Study of Pancreatic Enzyme Product in Pediatric Participants With Cystic Fibrosis and Exocrine Pancreatic InsufficiencyCompletedNCT00981214Phase 3Results posted
• Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)CompletedNCT00880100Phase 3Results posted
• A Randomized, Double-Blind, Dose Response-Control, Crossover Study to Evaluate the Safety and Efficacy of Two Doses of EUR-1008 (APT-1008) in Chronic Pancreatitis (CP) Participants With Exocrine Pancreatic Insufficiency (EPI)CompletedNCT00788593Phase 3Results posted
• Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency Due to Cystic FibrosisCompletedNCT00775528Phase 3Results posted
• Pilot and Feasibility Study for the Treatment of Pre-diabetes in Patients With Cystic FibrosisCompletedNCT00763412Not applicableResults posted
• Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic InsufficiencyCompletedNCT00743483Phase 2Results posted
• Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency (PEI) Due to Cystic Fibrosis (CF)CompletedNCT00690820Phase 3Results posted
• A Study of the Efficacy and Tolerability of Pancrelipase Microtablet (MT) Capsules for the Treatment of Cystic Fibrosis-dependent Exocrine Pancreatic InsufficiencyCompletedNCT00662675Phase 3Results posted
• Safety and Efficacy Study of Viokase® 16 for the Correction of SteatorrheaCompletedNCT00559364Phase 3Results posted
• Efficacy and Safety of Ultrase® MT20 in Improving the Coefficient of Fat Absorption (CFA) in Children With Cystic Fibrosis (CF) and Pancreatic Insufficiency (PI)CompletedNCT00513682Phase 3Results posted
• A Study to Investigate the Effect of Delayed Release Pancrelipase on Maldigestion in Patients With Exocrine Pancreatic Insufficiency Due to Chronic Pancreatitis and PancreatectomyCompletedNCT00414908Phase 3Results posted
• Safety and Efficacy Study of ULTRASE® MT20 in Participants With Cystic Fibrosis (CF) and Exocrine Pancreatic Insufficiency (PI)CompletedNCT00408317Phase 3Results posted
• Study to Evaluate the Safety and Efficacy of EUR-1008 (APT-1008) Pancreatic Enzyme Product in Participants With Cystic Fibrosis and Exocrine Pancreatic InsufficiencyCompletedNCT00297167Phase 3Results posted
• Safety of Stopping Pancreatic Enzyme Replacement Therapy in Children With Improved Pancreatic Function After Highly Effective Modulator TherapyCompletedNCT07632768Phase 4
• A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy SubjectsActive, not recruitingNCT07285863Phase 4
• Investigation on the Current Situation and Risk Factors Analysis of Exocrine Insufficiency in Chronic PancreatitisCompletedNCT06946108
• Magnesium Supplementation in Simultaneous Pancreas-Kidney TransplantationCompletedNCT06766786
• Medication Adherence to Phone-supervised Pancreatic Enzyme Replacement TherapyActive, not recruitingNCT06581653Not applicable
• AI Evaluation of Pancreatic Exocrine Insufficiency in CP PatientsCompletedNCT06278272
• Screening for Pancreatic Exocrine Insufficieny in Metabolic Associated Fatty Liver Disease PatientsStatus unknownNCT05804409
• PE-1 in the Diagnosis of Pancreatic Exocrine InsufficiencyCompletedNCT05791110Not applicable
• Evaluating the Utility of RELiZORB™ for Treating Feeding Intolerance in Critically Ill Adults With Multi-Organ FailureActive, not recruitingNCT05710315Not applicable
• Hypoglycemia and Glucagon Response in CFCompletedNCT05700604
• Exocrine Pancreatic Insufficiency After Acute Pancreatitis and Pancreatic Enzyme Replacement TherapyStatus unknownNCT05480241Not applicable
• PERT to Improve Quality of Life in Patients Undergoing Pancreaticoduodenectomy: A Pilot Randomized Controlled TrialActive, not recruitingNCT05466838Not applicable
• Registry of Pancreatic Exocrine Insufficiency: Enzyme Dose Requirements and Outcomes in Pancreatic Exocrine Insufficiency Across AetiologiesCompletedNCT05450627
• Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Exocrine Pancreatic Dysfunction in Type 1 DiabetesCompletedNCT05385211
• Endotherapy for Painless Chronic PancreatitisStatus unknownNCT05261997Not applicable
• Impact of Pancreatic Endoscopic Drainage on Exocrine Pancreatic Function in Unresectable Pancreatic CancerStatus unknownNCT05244174Not applicable
• Intestinal Microbiota Composition in Patients With Chronic Pancreatitis and Pancreatic Exocrine InsufficiencyCompletedNCT05132309
• Oral CDX-7108 in Healthy Adults and EPI SubjectsCompletedNCT05082051Phase 1
• Assessment of a PERT-free Nutritional Therapeutic Delivery System for Cystic FibrosisCompletedNCT04966897Not applicable
• Effect of CREON on Exocrine Pancreatic Insufficiency (EPI) SymptomsCompletedNCT04949828
• Role of Pancreatic Exocrine Secretion in Weight Gain After Pancreas TransplantationSuspendedNCT04690738
• BÜHLMANN FPELA in the Diagnosis of Exocrine Pancreatic InsufficiencyCompletedNCT04548778
• Study Of Effects Of Oral CREON Capsules In Adult Participants With Exocrine Pancreatic Insufficiency Not Due To Cystic Fibrosis, Chronic Pancreatitis, Pancreatectomy, Or Pancreatic CancerWithdrawnNCT04315311Phase 4
• Genomic Resources for Enhancing Available Therapies (GREAT1.0) StudySuspendedNCT04306939
• Phase 2 Combination Study With Escalating Doses of MS1819-SD on Top of a Stable Dose of PPEsCompletedNCT04302662Phase 2
• Diabetes/ Endocrine Surveillance in SDSTerminatedNCT04275479
• Recurrent Abdominal Pain and Exocrine Pancreatic InsufficiencyTerminatedNCT04231279Phase 3
• Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic CancerStatus unknownNCT04112836
• A Phase IIa Study With Escalating Dose of MS1819-SDCompletedNCT03481803Phase 2
• Equivalence Study to Compare Two Strengths of Creon in ChinaStatus unknownNCT03450772Phase 3
• Detection of Exocrine Pancreatic Insufficiency in Patients With Diarrhea and BloatingCompletedNCT03407534
• Pancreatic Exocrine Insufficiency After Bariatric SurgeryStatus unknownNCT03279653
• Utility of Point Shear-wave Elastography to Assess for Hepatic & Pancreatic Fibrosis in Pediatric CF PatientsStatus unknownNCT03264950Not applicable
• Prevalence of Exocrine Pancreatic Insufficiency in Patients With Decompensated CirrhosisCompletedNCT03236038
• RESULT: Reliable, Emergent Solution Using Liprotamase TreatmentStatus unknownNCT03051490Phase 3
• MRI to Characterize and Predict CF Liver Disease in PUSH CohortCompletedNCT02979340
• Pancreatic Exocrine Insufficiency in Acute PancreatitisCompletedNCT02563080
• A Study to Assess the Effect of Creon® on Pancreatic Exocrine Insufficiency in Subjects With Diabetes Mellitus Type 2WithdrawnNCT02009410Phase 4

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