Esophageal Squamous Cell Carcinoma: all 657 studies
Page 1 of 7. Open to participants first (276), then studies with results posted, then the rest; newest registration first within each.
- Radiotherapy Target Volume Delineation in Locally Advanced Esophageal Cancer in the Immunotherapy EraRecruitingNCT07858630
- PhII Study of Toripalimab Followed by Definitive CRT & Adjuvant Toripalimab in Locally Advanced ESCCNot yet recruitingNCT07836049Phase 2
- Immunotherapy Plus Anlotinib After Surgery for Esophageal Squamous Cell Cancer With Residual Tumor and Positive Lymph NodesNot yet recruitingNCT07830355Phase 2
- Neoadjuvant Sacituzumab Tirumotecan Plus Toripalimab in Locally Advanced Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07823270Phase 2
- Risk of Esophageal Cancer Returning After Immunotherapy, Chemotherapy, and SurgeryNot yet recruitingNCT07822906
- Sacituzumab Govitecan Combined With Tislelizumab for Locally Advanced/Metastatic Esophageal CancerRecruitingNCT07811752Phase 2
- Paclitaxel Polymeric Micelles and Cisplatin Plus Sintilimab as Neoadjuvant Therapy for Resectable Locally Advanced Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07799077Phase 2
- Adebrelimab With Famitinib and Chemotherapy as Neoadjuvant Therapy for ESCCRecruitingNCT07796113Phase 2
- Neoadjuvant Chemoradiotherapy Versus Neoadjuvant Immunochemotherapy for Resectable Esophageal Cancer: A Target Trial Emulation StudyNot yet recruitingNCT07778056
- Retlirafusp Alfa Combined With Chemoradiotherapy in Unresectable ESCCNot yet recruitingNCT07769866Not applicable
- Standardized MRI and Structured Reporting for Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07769658
- Neoadjuvant Chemoradiotherapy Combined With CTLA-4 Monoclonal Antibody Plus PD-1 Monoclonal Antibody for Locally Advanced Esophageal CancerRecruitingNCT07751055Phase 2
- Comparing ICI Followed By CCRT And CCRT Followed By Immunotherapy In Unresectable LA-ESCCRecruitingNCT07733830Phase 2
- A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCCRecruitingNCT07733180Phase 2
- A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid TumorsRecruitingNCT07730021Phase 1/2
- Early Response-guided Sequential Radiotherapy After Chemoimmunotherapy for Locally Advanced Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07721103Phase 2
- Breath Research Narrow Validation for Gastrointestinal Cancer DetectionRecruitingNCT07714538
- An Umbrella-designed Prospective Multicenter Randomized Open-label Superiority Trial Evaluating Multi-biomarker-guided Precision Therapy for First-line Treatment of Advanced Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07709533Phase 2
- Sacituzumab Tirumotecan (Sac-TMT/SKB264) Plus Tagitanlimab (KL-A167) in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma and Gastric/Gastroesophageal Junction AdenocarcinomaNot yet recruitingNCT07701681Phase 2
- SKB500 Combinations in Patients With Esophageal Squamous Cell CarcinomaRecruitingNCT07700667Phase 2
- Neoadjuvant Cardonilizumab Combined With Neoadjuvant Chemoradiotherapy Can Resect Locally Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT07699185Phase 2
- TDLN-Guided Lymphadenectomy After Neoadjuvant Immunochemotherapy for ESCCNot yet recruitingNCT07697898
- PD-1 Inhibitors Combined With Local Therapy at Different Timings in Oligometastatic ESCCRecruitingNCT07697859
- Becotatug Vedotin Plus Cisplatin and Radiotherapy in LA-ESCCNot yet recruitingNCT07697040Phase 1
- A Phase II Study of PD-1/IL-2α-bias Bispecific Antibody Fusion Protein Monotherapy in Advanced Esophageal Squamous Cell Carcinoma After Failure of Prior ICI Plus Platinum-Based ChemotherapyNot yet recruitingNCT07688291Phase 2
- Becotatug Vedotin Plus Tislelizumab and Low-Dose Lenvatinib for Advanced Esophageal Squamous Cell Carcinoma, Phase IINot yet recruitingNCT07686926Phase 2
- Neoadjuvant Short-Course Radiotherapy Plus Tislelizumab and Chemotherapy for Locally Advanced Resectable Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07678580Phase 2
- Precision Medicine for Immunotherapy-Resistant Advanced Esophageal CancerNot yet recruitingNCT07653451Phase 2/3
- Adebrelimab Combined With Neoadjuvant Chemotherapy in Borderline Resectable Locally Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT07638436Phase 2
- Surgery vs. Radical Chemoradiotherapy for Esophageal SCC After Neoadjuvant ImmunochemotherapyRecruitingNCT07629817Phase 3
- A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.Not yet recruitingNCT07623642Phase 2
- A Study of HS-20093 in Patients With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC)Not yet recruitingNCT07621601Phase 3
- Retlirafusp Alfa Plus Chemotherapy as Neoadjuvant Therapy for Thoracic ESCCNot yet recruitingNCT07618910Phase 2
- A Study of IDP-001 in Advanced or Metastatic Solid TumorsRecruitingNCT07602842Phase 1/2
- Adebrelimab Combined With Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell CarcinomaRecruitingNCT07595770Phase 2
- A Prospective Study of Tumor-specific Tpex in Negative Lymph Nodes for Predicting Pathological Complete Response to Neoadjuvant PD 1 Therapy in Esophageal CancerNot yet recruitingNCT07573397
- Infiltration Pattern of Locally Advanced ESCCEnrolling by invitationNCT07567716
- Induction Chemo-Immunotherapy + Radiotherapy vs Concurrent Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT07559045Phase 2
- A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United StatesRecruitingNCT07554521Phase 2
- A Study of BL-B01D1 in Combination With Tislelizumab ±5-Fluorouracil Versus Platinum-Based Chemotherapy Plus Tislelizumab as First-line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus02)RecruitingNCT07554456Phase 2/3
- Tpex Subsets in Negative Tumor Draining Lymph Nodes for Predicting the Efficacy of PD 1 Inhibitors in Advanced or Recurrent Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07533357
- Intensive Nutritional Support in Conversion Therapy for Locally Advanced Unresectable ESCCRecruitingNCT07519486Phase 2
- Camrelizumab, Chemotherapy and Ivarmacitinib in Patients With Resectable Esophageal Squamous Cell CarcinomaRecruitingNCT07505186Phase 2
- A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors TypesRecruitingNCT07503808Phase 1
- Tumor Microenvironment Changes After Neoadjuvant Chemo-Immunotherapy in Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07482774
- KC1036 in Combination With PD-1 Antibody and Platinum-based Chemotherapy for First-line Advanced Esophageal CancerRecruitingNCT07481058Phase 2
- QLC5508 vs. Chemotherapy in Pretreated Advanced or Metastatic Esophageal Squamous Cell CarcinomaRecruitingNCT07463573Phase 3
- Efficacy and Safety of Neo-CRT Plus Serplulimab, Nimotuzumab in Patients With Locally Advanced Resectable ESCCRecruitingNCT07457528Phase 2
- Time-of-Day of Immunotherapy Infusion in Neoadjuvant Immunochemotherapy for Thoracic ESCCRecruitingNCT07452601Phase 2
- Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical StudyRecruitingNCT07437898Phase 2
- A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F)RecruitingNCT07405151Phase 1/2
- Short-course Radiotherapy Combined With Serplulimab and Chemotherapy as Neoadjuvant Treatment for Resectable ESCCNot yet recruitingNCT07403435Phase 2
- Becotatug Vedotin ± Anti-PD-1 in Pretreated Advanced ESCCRecruitingNCT07403136Phase 2
- A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCCRecruitingNCT07385001Phase 1/2
- Indocyanine Green-guided Omental Shield Anastomosis for Cervical Esophagogastric Anastomosis in Minimally Invasive McKeown EsophagectomyNot yet recruitingNCT07376876Phase 2
- MR-Guided Radiotherapy Dose Escalation Trial for Esophageal Squamous Cell CarcinomaRecruitingNCT07359417Phase 1
- Standardized Management of Esophageal Fistula in Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07353541
- Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal DissectionNot yet recruitingNCT07343869
- Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell CarcinomaRecruitingNCT07339488Phase 2
- Neoadjuvant Immunotherapy Combined With Chemotherapy Sequenced With Endoscopic Resection for Esophageal Cancer (Endosurgery-02)RecruitingNCT07317609Phase 1
- Nimotuzumab,Camrelizumab, and Neoadjuvant Chemotherapy（nCT） in the Treatment of Esophageal Squamous Cell CarcinomaEnrolling by invitationNCT07312578Phase 2
- The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell CarcinomaRecruitingNCT07290010Phase 2
- First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid TumorsRecruitingNCT07284186Phase 1
- A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsRecruitingNCT07277413Phase 1
- A Phase II Study of Toripalimab Plus Chemotherapy and Low-Dose Radiotherapy for Neoadjuvant Therapy-Refractory Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07272291Phase 2
- Efficacy and Safety of Neoadjuvant Envafolimab Combined With Albumin-bound Paclitaxel and Carboplatin for Resectable Locally Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT07266493Phase 2
- Integrated Cf-miRNA and Exosomal miRNA Signature for Early Detection of Esophageal Squamous Cell CarcinomaRecruitingNCT07266363
- A Study of SYS6010, Enlonstobart, and Chemotherapy for First-Line Treatment of Esophageal Squamous Cell Carcinoma.Not yet recruitingNCT07251062Phase 2/3
- Stratified Treatment in Unresectable Locally Advanced ESCC Without Progression After Chemoimmunotherapy Induction Plus CCRT: Toripalimab Consolidation vs observation--a Prospective, Randomized, Controlled Phase III Multicenter StudyRecruitingNCT07246330Phase 3
- Neoadjuvant Ivonescimab（AK112） Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell CarcinomaRecruitingNCT07244978Phase 2
- A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid TumorsRecruitingNCT07229313Phase 1
- A Noninvasive and Screening miRNA Signature for Gastrointestinal CancerRecruitingNCT07224750
- A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4Enrolling by invitationNCT07218003Phase 1
- A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell CarcinomasRecruitingNCT07217171Phase 1
- Phase II Study Evaluating Safety and Efficacy of Tislelizumab for Elderly Patients Unfit for Chemotherapy, With Advanced Esophageal Squamous-cell CarcinomaRecruitingNCT07205731Phase 2
- A Study of IPM514 in Patients With Esophageal Squamous Cell Carcinoma.Not yet recruitingNCT07203898Phase 1
- 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid TumorsRecruitingNCT07189871Phase 1/2
- Ivonescimab Plus Short-Course Hypofractionated Radiotherapy as Second-Line Therapy for Esophageal Squamous Cell CarcinomaRecruitingNCT07188103Phase 2
- Consolidation of Toripalimab and Capecitabine After Chemoradiotherapy in ESCCRecruitingNCT07177794Phase 3
- Endostatin Adenovirus With Checkpoint Inhibitor in Advanced Head and Neck or Esophageal CancerNot yet recruitingNCT07154108Phase 1
- Brachytherapy With Radiotherapy and Immunotherapy: Guided HDR Trial in Esophageal Squamous Cell CarcinomaRecruitingNCT07152678Phase 2
- Multi-omics Monitoring of Dynamic Evolution in Esophageal Squamous Cell Carcinoma: PKU-ESCC-MonitorNot yet recruitingNCT07152535
- A Single-center, Multicohort, Phase II Clinical Study Evaluating the Combination Therapy of Sacituzumab Tirumotecan in Patients With Unresectable, Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07128693Phase 2
- A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway AlterationsRecruitingNCT07109726Phase 1/2
- A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid TumorsRecruitingNCT07090499Phase 1
- Deep Learning Model Predicts Pathological Complete Response of Esophageal Squamous Cell Carcinoma Following Neoadjuvant ImmunochemotherapyRecruitingNCT07088354
- Surufatinib in Combination With Neoadjuvant Chemo-immunotherapy and Concurrent Chemoradiotherapy for Patients With Unresectable Locally Advanced Esophageal Squamous Cell CarcinomaRecruitingNCT07086469Phase 2
- A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid TumorsRecruitingNCT07085091Phase 1
- An Observational Study on the Safety and Efficacy of Immunotherapy Combined With Concurrent Chemoradiotherapy in Elderly Patients With Esophageal Squamous Cell CarcinomaRecruitingNCT07080437
- Adjuvant Immunotherapy for Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07067450Not applicable
- Oncolytic Virus in Esophageal Squamous Cell CarcinomaRecruitingNCT07061704Phase 1/2
- QL1706 Plus Celecoxib in Advanced Esophageal Squamous Cell CarcinomaNot yet recruitingNCT07049185Phase 2
- Study of Tislelizumab Combined With Chemoradiotherapy and Surgery for Unresectable Esophageal Squamous Cell CarcinomaRecruitingNCT07039162Phase 2
- Immunochemotherapy ± Salvage Chemoradiation for Local Recurrence of Esophageal Squamous Cell Carcinoma After Definitive ChemoradiotherapyEnrolling by invitationNCT07016737Phase 3
- Neoadjuvant Radiochemotherapy Combined With Cadonilizumab for Local Advanced Esophageal Squamous Cell CancerRecruitingNCT07016724Phase 2
- Nimotuzumab Plus Definite Chemoradiotherapy(dCRT) in Elderly Patients With Esophageal Squamous Cell CarcinomaRecruitingNCT06988956Phase 2
- Diagnostic Accuracy of Endocytoscopy for Superficial Esophageal NeoplasiaEnrolling by invitationNCT06984055
- SLND Versus Non-Dissection Following ESD for T1a Stage Esophageal Squamous Cell CarcinomaNot yet recruitingNCT06979986Not applicable
- Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid TumorsRecruitingNCT06975410Phase 1/2
- Evaluation of Skin Tests in Biotherapy AllergiesRecruitingNCT06971848Not applicable