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Demyelinating Autoimmune Diseases, CNS clinical trials

The registry lists 25 studies for Demyelinating Autoimmune Diseases, CNS across more than 10 countries. 8 are recruiting or about to start. 2 of them are mainly about Demyelinating Autoimmune Diseases, CNS (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its 6 narrower conditions too, such as Multiple Sclerosis: 3,813 studies, 764 open.

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Status

Completed
12
Recruiting
5
Not yet recruiting
3
Status unknown
3
Active, not recruiting
1
Suspended
1

Phase

Phase 1
3
Phase 2
2
Phase 3
2
Phase 4
1

Where

United States
11
France
4
Canada
2
United Kingdom
2
China
2
Spain
1

Who runs them

University of Texas at Austin (2) · Regeneris Medical (1) · EMD Serono (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · University of Exeter (1) · Sheffield Teaching Hospitals NHS Foundation Trust (1) · University of Washington (1) · First Affiliated Hospital of Wenzhou Medical University (1)

What is being tested here

Drugs under test in Demyelinating Autoimmune Diseases, CNS studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Rituximab111
Metformin001
PIPE-791001
Mitoxantrone001
Alemtuzumab011

Coming up

1phase 3 study under way
3studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3, phase 3 first

Who these studies take

Of the 5 Demyelinating Autoimmune Diseases, CNS studies recruiting now, 4 (80%) set no upper age limit and 0 (0%) stop at 75 or younger. 2 (40%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (40%) take healthy volunteers.

Recruiting studies that take each age, of 5
AgeWomenMen
102 (40%)2 (40%)
185 (100%)5 (100%)
305 (100%)5 (100%)
405 (100%)5 (100%)
505 (100%)5 (100%)
655 (100%)5 (100%)
755 (100%)5 (100%)
854 (80%)4 (80%)

Across all 25 studies, recruiting or not: 48% stop at 75 or younger and 44% at 65; 16% take children; 0% are for women only and 0% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 14, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 25 of 25. search them.