Cholangiocarcinoma: all 930 studies
Page 1 of 10. Open to participants first (292), then studies with results posted, then the rest; newest registration first within each.
- SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-METRecruitingNCT07873450Phase 1/2
- A Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma With FGFR2 Fusion or Rearrangements After at Least 1 Prior Line of Systemic TherapyNot yet recruitingNCT07862998Phase 2
- Perioperative Retlirafusp Alfa(Anti-PD-L1/TGF-β Bifunctional Fusion Protein) Plus Famitinib and GEMOX-Based Hepatic Arterial Infusion Chemotherapy for Locally Advanced Intrahepatic Cholangiocarcinoma: A Multicenter, Single-Arm, Exploratory Phase II TrialRecruitingNCT07847710Phase 2
- Cryoablation Combined With Anlotinib Plus TQB2868 in Patients With Advanced Intrahepatic CholangiocarcinomaNot yet recruitingNCT07846267Phase 2
- HAIC Plus QL1706 & Bevacizumab in Unresectable HER2-Negative ICCRecruitingNCT07841574Phase 2
- Prognostic Evaluation and Systematic Re-Assessment of Cholangiocarcinoma TherapyNot yet recruitingNCT07814586
- Phase 2 Study of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract CancerNot yet recruitingNCT07793253Phase 2
- Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or CholangiocarcinomaRecruitingNCT07780838Phase 2
- Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CTNot yet recruitingNCT07768085Not applicable
- Combination Therapy Using Durvalumab and Histotripsy for Treatment of Intrahepatic CholangiocarcinomaRecruitingNCT07766187Phase 2
- Testing the Addition of Ivonescimab Combined With Standard Chemotherapy Compared to the Usual Chemotherapy and Immunotherapy Treatment for Patients With Advanced Biliary Tract CancerNot yet recruitingNCT07765433Phase 2/3
- Protective Mechanisms of Phycocyanin in Partial Hepatectomy-Associated Liver InjuryRecruitingNCT07760038Not applicable
- 68Ga-SorB PET/CT Imaging in Patients With Solid TumorsRecruitingNCT07760012Not applicable
- Investigating Precision Medicine in the Adjuvant Setting in Biliary Tract CancerNot yet recruitingNCT07745296Phase 3
- IKS04 Regimen in Advanced Solid Tumors That Express CA242Not yet recruitingNCT07738939Phase 1
- Precision Integrated Strategies and Efficacy Evaluation for Biliary Tract Cancers: An Umbrella Platform StudyNot yet recruitingNCT07729917Phase 2
- DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.RecruitingNCT07717437
- Inter-Individual Tumor Heterogeneity on 3D-MRE for Predicting Response to Conversion Therapy in Liver CancerNot yet recruitingNCT07716345
- Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump TherapyNot yet recruitingNCT07715903Phase 1
- Breath Research Narrow Validation for Gastrointestinal Cancer DetectionRecruitingNCT07714538
- Peritumoral MRE Stiffness for Predicting Resection Margin Status and Recurrence in Liver CancerNot yet recruitingNCT07704216
- Intraarterial Therapies Plus Tislelizumab Plus Lenvatinib Versus Tislelizumab Plus Gemcitabine-Cisplatin in Unresectable Intrahepatic CholangiocarcinomaNot yet recruitingNCT07691515Phase 3
- [18F]FTT Positron Emission Tomography/Computed Tomography to Predict Treatment Response in Patients Scheduled to Receive Gemcitabine, Cisplatin, and Durvalumab for Newly Diagnosed CholangiocarcinomaRecruitingNCT07673341Phase 2
- Pilot Study of Intermittent Fasting With Immune Checkpoint InhibitorsNot yet recruitingNCT07645742Not applicable
- Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract CancerRecruitingNCT07641036Phase 1/2
- Adjuvant Therapy for High-Risk Intrahepatic Cholangiocarcinoma: A Real-World StudyRecruitingNCT07640048
- Efficacy and Safety of Postoperative Concurrent Chemoradiotherapy for Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma: A Multicenter Prospective Phase II StudyRecruitingNCT07636824Phase 2
- A Multicenter, Prospective, Randomized, Open-label Phase Ib/II Study of Celecoxib Plus Pembrolizumab and Gemcitabine/Cisplatin Versus Pembrolizumab and Gemcitabine/Cisplatin in Patients With CK5/6-High Unresectable Locally Advanced or Metastatic Intrahepatic CholangiocarcinomaNot yet recruitingNCT07632235Phase 1/2
- A Phase II Study of GV20-0251 in Combination With Anti-PD-1 Monoclonal Antibodies in Patients With Unresectable, Locally Advanced, or Metastatic Solid Tumors.Not yet recruitingNCT07623642Phase 2
- EYEMAX® Versus SPYGLASS™ DS for Biliary Stricture DiagnosisNot yet recruitingNCT07620080Not applicable
- AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic CancerRecruitingNCT07619313Phase 1
- Safety and Efficacy of CD160-Enhanced Autologous Antigen-Specific T-Cells (BTC-Ag-T) in Advanced Biliary Tract CancerRecruitingNCT07614061Phase 1
- Study of Becotatug Vedotin Added to Standard Treatment for Advanced Bile Duct Cancer With EGFR MutationsNot yet recruitingNCT07598318Phase 2/3
- To Evaluate the Safety, Tolerability, and Preliminary Efficacy of XH001 Injection as Adjuvant Therapy in Patients With High-risk Recurrent Solid TumorsRecruitingNCT07594964Phase 1
- TCR1188-ABC Cells in KRAS-mutated CancersRecruitingNCT07594067Phase 1
- Chidamide Combined With Chemotherapy and Immunotherapy as First-line Treatment for Advanced Intrahepatic CholangiocarcinomaRecruitingNCT07570849Phase 2
- Adebrelimab Plus S-1 for Resected CholangiocarcinomaNot yet recruitingNCT07561775Phase 2
- Suprapapillary Metal Stent vs. Routine Transpapillary Drainage in Malignant Hilar Biliary Obstruction (SMART-B Trial)RecruitingNCT07558304Not applicable
- 18F-T2 PET/CT Imaging for CAIX Positive Solid TumorsRecruitingNCT07557225Not applicable
- Outcomes After Liver and Biliary Resection at a High-Volume CenterNot yet recruitingNCT07556835
- A Clinical Study to Evaluate the Efficacy and Safety of VG2025 in Intrahepatic CholangiocarcinomaRecruitingNCT07522476Phase 2
- The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced CholangiocarcinomaNot yet recruitingNCT07514533Phase 2
- A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid TumorsRecruitingNCT07488676Phase 1/2
- Olutasidenib DDI Study in Patients With IDH1 Mutation Positive MalignanciesRecruitingNCT07486713Phase 4
- FAPI-PET Value for the Initial Screening of Pancreatic and Biliary CancersRecruitingNCT07478523Phase 2
- Scout Dose of Resin MicrospheresRecruitingNCT07476651Not applicable
- A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) MutationRecruitingNCT07458347Phase 1
- TRACE-BTC. Relation of Biomarkers and Patients Reported Quality of Life to Outcomes in Patients With Biliary Tract Cancer: a Real- World CohortNot yet recruitingNCT07454486
- A Study of Liposomal Irinotecan Plus 5-FU/LV HAIC With Lenvatinib and a PD-1 Inhibitor in Advanced ICCNot yet recruitingNCT07432568Phase 2
- Preclinical Development of a 3D Bili-MRI Reconstruction Tool and an Artificial Intelligence Algorithm to Assist Endoscopists in Performing Endoscopic Retrograde Cholangiopancreatography (ERCP)Not yet recruitingNCT07401485
- Laryngopharyngeal Injury After Endotracheal Intubation Under General AnesthesiaRecruitingNCT07359586
- FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic CholangiocarcinomaNot yet recruitingNCT07353827Phase 2
- Hepatobiliary and Pancreatic Tumor BiobankNot yet recruitingNCT07344116
- Prospective Evaluation of 68Ga-FAPI PET in Biliary CancersRecruitingNCT07337850
- A First in Human Study of PLT012 in Participants With Solid Tumor CancersRecruitingNCT07337525Phase 1
- Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of MT-304 in Adults With Advanced HER2-Expressing Solid TumorsRecruitingNCT07334119Phase 1
- Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or MutationsNot yet recruitingNCT07328919Phase 3
- Adjuvant Chemotherapy for BTC Based on 3D-PTANot yet recruitingNCT07296666Phase 2
- PULSAR Combined With Immunotherapy and ChemotherapyRecruitingNCT07291947Phase 1/2
- Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCARecruitingNCT07291063
- Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) LevelsRecruitingNCT07282912Phase 2
- A Phase IIb Randomized Clinical Trial of Immune Checkpoint Inhibitor-based Maintenance Therapy in Patients With Advanced Biliary Tract CancerNot yet recruitingNCT07269158Phase 1/2
- A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract CancerRecruitingNCT07265674Phase 3
- Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver InjuryRecruitingNCT07263217Not applicable
- Phase II Study Evaluating Ivosidenib Maintenance After SOC Adjuvant Chemotherapy in Curative mIDH1 CholangiocarcinomaRecruitingNCT07260175Phase 2
- Repeated Endobiliary Radiofrequency Ablation Plus Durvalumab, Gemcitabine, and Cisplatin for Unresectable Extrahepatic CholangiocarcinomaRecruitingNCT07235007Not applicable
- A Noninvasive and Screening miRNA Signature for Gastrointestinal CancerRecruitingNCT07224750
- The Sarah Nanotechnology System for Treatment of Advanced Metastatic Solid Tumors Using Hyperthermia.RecruitingNCT07224464Not applicable
- REGULUS: MRI-guided Adaptive SABR for Liver CancersRecruitingNCT07223307Phase 2
- A Study of LY4337713 in Participants With FAP-Positive Solid TumorsRecruitingNCT07213791Phase 1
- A Randomized Trial of Surgical Decision-Making Guided by TDTP-RECISTNot yet recruitingNCT07208526Not applicable
- In-Depth Characterisation of Biliary Strictures and Hepato-Pancreato-Biliary Focal Lesions for Development of New Technologies to Tackle Hepato-Pancreato-Biliary CancersRecruitingNCT07206355
- Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion ChemotherapyRecruitingNCT07201519Phase 2
- A Cell-free DNA Methylation Blood-Based Test for Biliary Tract Cancers ScreeningRecruitingNCT07176962
- A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid TumorsRecruitingNCT07169734Phase 1/2
- Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma (POELH-III)RecruitingNCT07161869
- Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft PancreasRecruitingNCT07155525Not applicable
- PErioperative CISGEM + Rilvegostomig in High-Risk Resectable Intra Hepatic CholangioCarcinomaNot yet recruitingNCT07128290Phase 2
- Improving a Bile Duct Drainage Procedure in Patients With Inoperable Cancer Blocking the Bile Ducts: Comparing Two Types of Endoscopically Placed Internal Stents to Prevent Blockage of a Lumen Apposing Metal StentNot yet recruitingNCT07115420Not applicable
- A Study of GV20-0251 in Advanced or Refractory Solid TumorsRecruitingNCT07106827Phase 1
- Exploring the Safety and Efficacy of Sacituzumab Tirumotecan Combined With Pucotenlimab in the Treatment of Advanced CholangiocarcinomaRecruitingNCT07105852Phase 2
- An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Characterization of Tumor Heterogeneity for Precision Diagnosis and Treatment Optimization in Liver Cancer.RecruitingNCT07101237
- Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic CholangiocarcinomaRecruitingNCT07070700Phase 2
- Spanish Registry of Direct Cholangiopancreatoscopy by Single OperatorNot yet recruitingNCT07064447
- A Prospective Phase II Study of Postoperative Concurrent Chemoradiotherapy in Patients With Intrahepatic CholangiocarcinomaRecruitingNCT07063888Phase 2
- Streamlining Radioembolization for CCC and Metastatic Liver CancerRecruitingNCT07043387
- Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar CholangiocarcinomaRecruitingNCT07030140Phase 2
- Sequential Anti-Angiogenic Therapy After Immunotherapy in Advanced Biliary Tract CancerRecruitingNCT07025174Phase 2
- A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid TumorsRecruitingNCT07020221Phase 1/2
- Bile Omics for Diagnosing Indeterminate Biliary StricturesRecruitingNCT07007832
- Adjuvant Immunotherapy Combined With ChemoRadiation for Patients With High-risk Resectable Extrahepatic Cholangiocarcinoma（AICRC）Enrolling by invitationNCT06997913
- Outpatient Versus Inpatient Care Pathway for Intra-arterial Treatment of Primary Liver Cancer (CHOC)RecruitingNCT06990659Not applicable
- Liver Transplantation for Unresectable Perihilar CholangiocarcinomaRecruitingNCT06986486
- Evaluation of Skin Tests in Biotherapy AllergiesRecruitingNCT06971848Not applicable
- Raman Spectroscopy in the Diagnosis of Extrahepatic Cholangiocarcinoma - a Pilot StudyRecruitingNCT06964425Not applicable
- Gem+Nab-P+LEN+TIS for Advanced Unresectable BTC (GALENT-BT)Enrolling by invitationNCT06963060Phase 2
- Personalized Tumor Neoantigen mRNA Therapy for Advanced Intrahepatic CholangiocarcinomaRecruitingNCT06956716Phase 1/2
- Second-line Regimen Combined With Radiotherapy Versus Without Radiotherapy in Patients With Locally Advanced/Oligometastatic ICC After Failure of First-line Treatment：an Open-label, Randomized, Controlled Phase II Clinical StudyNot yet recruitingNCT06946849Phase 2
- A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICCRecruitingNCT06925516Phase 2
- Neoadjuvant Gemcitabine and Cisplatin in Combination With Perioperative Pembrolizumab Versus Upfront Surgery for Patients With Primary Resectable and Borderline Resectable Perihilar and Distal CholangiocarcinomaRecruitingNCT06923475Phase 2/3