Moyamoya Disease clinical trials
The registry lists 62 studies for Moyamoya Disease across 8 countries. 30 are recruiting or about to start. 51 of them are mainly about Moyamoya Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Beijing Tiantan Hospital (14) · Seoul National University Hospital (6) · Huashan Hospital (4) · Capital Medical University (4) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (3) · Assistance Publique - Hôpitaux de Paris (2) · Great Ormond Street Hospital for Children NHS Foundation Trust (2) · National Taiwan University Hospital (2)
What is being tested here
Drugs under test in Moyamoya Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Erythropoietin | 0 | 0 | 2 |
| Butylphthalide | 0 | 1 | 1 |
| Sevoflurane | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Safety and Efficacy of RIC in Pediatric Moyamoya Disease Patients Treated With Revascularization Therapy · Capital Medical University
- Nov 2026Chinese Herbal Therapy (Qiqi Shengmai Formula) for Moyamoya Vasculopathy: The CHIMES Trial · Fudan University
- Nov 2026Long-term Outcomes of Conservative Management in Patients with Moyamoya Disease and Their First-degree Relatives (LAMORA) · Beijing Tiantan Hospital
- Dec 2026Remimazolam Consumption: TCI vs. Manual Infusion · Seoul National University Hospital
- Dec 2026Managing Transient Neurologic Episodes in Surgery for Moyamoya Disease · Stanford University
- Jan 2027Clinical Evaluation of the Safety and Efficacy of "Buyan Huan Wu Tang" Combined With Atorvastatin in the Treatment of Atypical Pneumonia · The First Affiliated Hospital with Nanjing Medical University
- Jan 2027Clinical Safety and Efficacy Evaluation of the Blood-cooling and Stasis-removing Formula as an Adjunct to Atorvastatin in the Treatment of Hemorrhagic Moyamoya Disease. · The First Affiliated Hospital with Nanjing Medical University
- Jun 2027Neurosurgical Outcome Network · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
- Jul 2027Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients · University Hospital Tuebingen
- Sep 2027The Symani Restore Study · Jacobs institute
Who these studies take
Of the 22 Moyamoya Disease studies recruiting now, 9 (41%) set no upper age limit and 10 (45%) stop at 75 or younger. 9 (41%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (23%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (36%) | 8 (36%) |
| 18 | 20 (91%) | 20 (91%) |
| 30 | 20 (91%) | 20 (91%) |
| 40 | 20 (91%) | 20 (91%) |
| 50 | 20 (91%) | 20 (91%) |
| 65 | 16 (73%) | 16 (73%) |
| 75 | 13 (59%) | 13 (59%) |
| 85 | 11 (50%) | 11 (50%) |
Across all 62 studies, recruiting or not: 52% stop at 75 or younger and 44% at 65; 34% take children; 0% are for women only and 0% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered4
- Clinical Evaluation of the Safety and Efficacy of "Buyan Huan Wu Tang" Combined With Atorvastatin in the Treatment of Atypical PneumoniaOct 30, 2026NCT07906652
- Development and Validation of Risk Prediction Models for Stroke and Cognitive Impairment in Moyamoya Disease and Moyamoya SyndromeOct 26, 2026NCT07894107
- Clinical Safety and Efficacy Evaluation of the Blood-cooling and Stasis-removing Formula as an Adjunct to Atorvastatin in the Treatment of Hemorrhagic Moyamoya Disease.Oct 26, 2026NCT07894640
- Efficacy and Safety of Ischemic Preconditioning Therapy Versus Optimal Medical Therapy in Reducing the Recurrence of Ischemic Events in Symptomatic Moyamoya DiseaseOct 22, 2026NCT07889531
Studies
Recruiting first, then most recently updated. Showing 50 of 62. Browse all 62 → or search them.
- Safety and Efficacy of RIC in Pediatric Moyamoya Disease Patients Treated With Revascularization TherapyRecruitingNCT03546309Not applicable1 country
- Application of Digital Twins' Technology in Patients Who Had a Stroke, With Moyamoya Disease and With Cerebral Amyloid Angiopathy (CAA) During the Secondary Prevention Phase: A Proof of Concept Using a Randomized Control Trial (Clinical Study 6, STRATIF-AI Project)RecruitingNCT06714097Not applicable1 country
- Clinical Evaluation of the Safety and Efficacy of "Buyan Huan Wu Tang" Combined With Atorvastatin in the Treatment of Atypical PneumoniaEnrolling by invitationNCT07906652Early Phase 11 country
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT017931681 country
- Efficacy and Safety of Ischemic Preconditioning Therapy Versus Optimal Medical Therapy in Reducing the Recurrence of Ischemic Events in Symptomatic Moyamoya DiseaseRecruitingNCT07889531Not applicable1 country
- Clinical Safety and Efficacy Evaluation of the Blood-cooling and Stasis-removing Formula as an Adjunct to Atorvastatin in the Treatment of Hemorrhagic Moyamoya Disease.Enrolling by invitationNCT07894640Early Phase 11 country
- Development and Validation of Risk Prediction Models for Stroke and Cognitive Impairment in Moyamoya Disease and Moyamoya SyndromeRecruitingNCT078941071 country
- Cognitive-Motor Incorporated Training and Its Relations in Cerebrovascular Diseases With Cognitive and Motor ImpairmentsRecruitingNCT07144930Not applicable1 country
- 5T MRI and Metabolomics-Based Hemorrhage Risk Prediction in Moyamoya DiseaseRecruitingNCT077815791 country
- Evaluating Antiplatelet and Physical Therapy for Slowing Progression in Mild Moyamoya Disease.Not yet recruitingNCT07762547Not applicable1 country
- Application of Extended Reality (XR)-Assisted Computed Tomography (CT)-Guided Localization in Extracranial-intracranial (EC-IC) Bypass SurgeryRecruitingNCT077114571 country
- Remimazolam Consumption: TCI vs. Manual InfusionRecruitingNCT07377695Not applicable1 country
- Family-Based Moyamoya Susceptibility and Early DetectionRecruitingNCT075173541 country
- Neurosurgical Outcome NetworkRecruitingNCT067240291 country
- Biomarker-Led Optimization of Successful Surgical Outcomes in MoyamoyaEnrolling by invitationNCT066340041 country
- Cardiac Index-Guided Intraoperative Hemodynamic Management in Pediatric Moyamoya SurgeryRecruitingNCT07304947Not applicable1 country
- Chinese Herbal Therapy (Qiqi Shengmai Formula) for Moyamoya Vasculopathy: The CHIMES TrialNot yet recruitingNCT07286110Phase 11 country
- The Symani Restore StudyRecruitingNCT07140731Not applicable1 country
- Treatment of Moyamoya Disease With iPSC-derived ExosomesRecruitingNCT07065409Phase 11 country
- Managing Transient Neurologic Episodes in Surgery for Moyamoya DiseaseRecruitingNCT068803411 country
- Study on the Mechanism of Cognitive Impairment in Patients with Moyamoya DiseaseRecruitingNCT068328391 country
- Functional Magnetic Resonance-Based Observations of Brain Networks in Moyamoya Disease Patients Under AnesthesiaRecruitingNCT060416591 country
- Study on Evaluating the Effectiveness of Statins in the Treatment of Moyamoya DiseaseRecruitingNCT068174341 country
- Long-term Outcomes of Conservative Management in Patients with Moyamoya Disease and Their First-degree Relatives (LAMORA)RecruitingNCT053327561 country
- Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya PatientsRecruitingNCT06330818Not applicable1 country
- Prognostic Prediction Model in Patients With Moyamoya Disease Undergoing Revascularization SurgeryNot yet recruitingNCT060515521 country
- Registry of Multicenter Brain-Heart Comorbidity in ChinaRecruitingNCT059617481 country
- Remote Ischemic Conditioning in Adult Moyamoya Disease PatientsNot yet recruitingNCT05860946Not applicable
- Angiogenic Markers in Cerebrovascular Disease (ANFIS)Enrolling by invitationNCT04240119
- The Evolution and Prognosis of Moyamoya DiseaseRecruitingNCT056190681 country
- Florida Cerebrovascular Disease Biorepository and Genomics CenterActive, not recruitingNCT054919801 country
- RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)CompletedNCT069355781 country
- A Study of Cerebral Perfusion With tDCS in Chronic HypoperfusionCompletedNCT06477107Not applicable1 country
- Super-resolution Clinical Brain UltrasoundCompletedNCT057855981 country
- Functional Disorders Moya Moya Young PatientsCompletedNCT057725721 country
- Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya PatientsActive, not recruitingNCT03882060Not applicable1 country
- RNF213 Variants and Collateral Vessels in Moyamoya DiseaseCompletedNCT049065641 country
- The Role of m6A RNA Modification in Moyamoya DiseaseStatus unknownNCT046960941 country
- NIRS to Evaluate Haemodynamic Reserve in Paediatric MoyamoyaSuspendedNCT05160454Not applicable1 country
- Characteristics and Outcomes of Childhood Moyamoya in the UKCompletedNCT024343021 country
- Moya Moya Syndrome With or Withtout Sickle Cell DiseaseStatus unknownNCT050503441 country
- Safety and Efficacy of Remote Ischemic Conditioning Combined EDAS on Ischemic Moyamoya DiseaseStatus unknownNCT04917003Not applicable1 country
- Gut Microbiota in Patients With Moyamoya DiseaseStatus unknownNCT048907821 country
- The Safety and Efficacy of RIC on Adult Moyamoya DiseaseCompletedNCT04012268Not applicable1 country
- Precision Bypass in Patients With Moyamoya DiseaseWithdrawnNCT03516851Not applicable1 country
- NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular EventsStatus unknownNCT04205578Phase 31 country
- The Effect of RIC on TIA/Stroke in Children With Moyamoya DiseaseStatus unknownNCT03821181Not applicable1 country
- Effects of Remote Ischemic Pre-Conditioning in Moyamoya Disease PatientsSuspendedNCT04064658Not applicable1 country
- Effect of Surgical Revascularization on Hemorrhagic Moyamoya DiseaseStatus unknownNCT03627975Not applicable1 country
- Relationship Between Endothelial Progenitor Cells and Revascularization Effect of Moyamoya DiseaseStatus unknownNCT036137011 country