Brain Edema clinical trials
The registry lists 92 studies for Brain Edema across more than 10 countries. 21 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-25.
Status
- Completed
- 38
- Status unknown
- 15
- Not yet recruiting
- 12
- Recruiting
- 8
- Terminated
- 8
- Withdrawn
- 7
Phase
- Phase 2
- 15
- Phase 1
- 10
- Phase 3
- 8
- Phase 4
- 5
- Early Phase 1
- 2
Where
- United States
- 26
- China
- 22
- Canada
- 4
- Italy
- 4
- United Kingdom
- 4
- Egypt
- 4
Who runs them
Celtic Pharma Development Services (4) · Xuanwu Hospital, Beijing (4) · Children's Hospital Medical Center, Cincinnati (3) · University of California, Davis (2) · Second Affiliated Hospital, School of Medicine, Zhejiang University (2) · Virginia Commonwealth University (2) · Shanghai Jiao Tong University Affiliated Sixth People's Hospital (2) · Sheba Medical Center (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 92 — search for more.
- Early Prophylactic Versus Late Salvage Recombinant Human Endostatin in Managing Radiosurgery-Induced Brain Injury for NSCLC Brain Metastases.Not yet recruitingNCT07841106Phase 2
- Transcranial Doppler Evaluation After Endovascular Thrombectomy for Acute Ischemic Stroke (PRECISE-TCD)Not yet recruitingNCT070133961 country
- TENS of Auricular Vagal Nerve for Radiation NecrosisNot yet recruitingNCT07680127Not applicable1 country
- Bedside Ultrasound Measurement of Optic Nerve Sheath Diameter for Detecting Raised Intracranial PressureNot yet recruitingNCT07799714
- International Multi-center Retrospective Study of Patients With Serum Sodium ≤110 mmol/L to Determine the Relationship Between Osmotic Demyelination Syndrome (ODS) and Rapid Correction of HyponatremiaEnrolling by invitationNCT075760361 country
- A Trial of Adacolumn on Cerebral Edema After Anterior Circulation Ischemic StrokeNot yet recruitingNCT07386262Not applicable1 country
- ONSD Trajectory in Rebound ICHNot yet recruitingNCT077227021 country
- Modulating Inflammation in Neuro-TraumaNot yet recruitingNCT07510074Not applicable1 country
- Butylphthalide for Brain Edema After Endovascular TreatmentNot yet recruitingNCT07528456Phase 41 country
- Early Prophylactic Decompressive Hemicraniectomy Following Endovascular Therapy in Large Hemispheric Infarct TrialRecruitingNCT07118345Not applicable1 country
- Antisecretory Factor In Severe Traumatic Brain InjuryRecruitingNCT04117672Phase 21 country
- Effect of Volatile- Based Versus Total Intravenous Anesthesia on Brain Homeostasis and Neurocognitive OutcomeRecruitingNCT06779890Phase 41 country
- High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral EdemaNot yet recruitingNCT06515145Not applicable1 country
- Setting Families on a Positive Path to Recovery After Pediatric TBI: Road-to-RecoveryRecruitingNCT05622461Not applicable1 country
- Early Identification of Malignant Brain Edema in laRge Artery oCclusive Stroke After Endovascular Therapy (EMBRACE Study)RecruitingNCT064518871 country
- Haemodynamical Optimization During Brain SurgeryRecruitingNCT04114799Not applicable1 country
- Clinical Significance of DKK2 Protein in Cerebral Ischemia-reperfusion InjuryRecruitingNCT055852551 country
- Rapid Local Ischemic Postconditioning in Acute Ischemic StrokeNot yet recruitingNCT06307743Not applicable
- Safety and Efficacy of ABX-101 in Participants Aged 18 to 50 Years of Age With Moderate to Severe Traumatic Brain InjuryNot yet recruitingNCT06096415Phase 2
- Non-invasive Monitoring and Serum Marker Study in Children With Cerebral EdemaNot yet recruitingNCT06017635
- Inflammation and Coagulation Factors for Predicting Cerebral Edema After SAHRecruitingNCT060090161 country
- Implementation of Neuro Lung Protective VentilationActive, not recruitingNCT03243539Not applicable1 country
- Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH)Active, not recruitingNCT05020535Phase 21 country
- Wet and Dry Biomarkers to Predict Secondary Injury in Stroke: From Bench to Bedside - The NIMBLE StudyCompletedNCT074226361 country
- Trial of Dexamethasone for Traumatic Brain Injured Patients With Brain Contusions and Pericontusional EdemaTerminatedNCT04303065Phase 31 country
- Local Ischemic Postconditioning in Acute Ischemic StrokeCompletedNCT06526429Not applicable1 country
- AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head InterpretationCompletedNCT060185451 country
- Automatic PredICtion of Edema After StrokeActive, not recruitingNCT040576903 countries
- Bleeding Intracerebral Hemorrhage With Early Invasive Intracranial Pressure Monitoring TrialCompletedNCT05593380Not applicable1 country
- "The Effect of Trimetazidine on the Clinical Outcome of Acute Ischemic Stroke Patients"CompletedNCT06656442Phase 31 country
- Treating Brain Swelling in Pediatric Cerebral MalariaCompletedNCT03300648Phase 31 country
- Fingolimod as a Treatment of Cerebral Edema After Intracerebral HemorrhageCompletedNCT04088630Early Phase 11 country
- A Trial of HRS8179 on Brain Swelling After Large Hemispheric InfarctionCompletedNCT05690711Phase 21 country
- Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric InfarctionTerminatedNCT02864953Phase 324 countries
- Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with GlioblastomaWithdrawnNCT05773664Phase 1
- Risk Factors Associated With High Altitude Sickness: A Case-Control StudyCompletedNCT060394751 country
- Spectroscopic and Diffusion Weighted Analysis of the Effects of Dexamethasone on High Altitude Cerebral Oedema (HACE)CompletedNCT03341676Phase 11 country
- Swiss Prospective Autologous Bone Flap Resorption StudyTerminatedNCT023209551 country
- Diabetic Ketoacidosis Diagnosis and ManagementCompletedNCT063277371 country
- A Predictive Model and Scoring System for Severe Complications After Endovascular ThrombectomyCompletedNCT062900761 country
- The Effect of Lumbar CSF Drainage on the Neurologic Outcome Improvement in OHCA Underwent TTMCompletedNCT043289741 country
- The Tolerability, Safety, and PK Characteristics of SIM1910-09 in Healthy Chinese VolunteersCompletedNCT05200728Phase 11 country
- Early Induced Hypernatremia for the Prevention and Management of Brain EdemaWithdrawnNCT02798601Not applicable
- Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients With Brain DiseasesCompletedNCT057963491 country
- Effects of Intraoperative GDFT on the Postoperative Brain EdemaCompletedNCT03323580Not applicable1 country
- Acute Ischaemic STROKE: From LAboratory to the Patient's BEDStatus unknownNCT05725694
- SMCV Assessment on Brain Swelling in Patients With SAH From Ruptured Artery AneurysmStatus unknownNCT057147351 country
- SMCV Assessment on Brain Swelling in Patients With SAHStatus unknownNCT056966391 country
- Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)TerminatedNCT02460874Phase 1/21 country
- Correlation of Trans Cranial Doppler Ultrasound and CT Scan in Monitoring of Posttraumatic Brain EdemaCompletedNCT048344531 country