Anaphylaxis clinical trials
The registry lists 100 studies for Anaphylaxis across more than 10 countries. 20 are recruiting or about to start. 51 of them are mainly about Anaphylaxis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (5) · Assistance Publique - Hôpitaux de Paris (5) · Nasus Pharma (4) · University Hospital, Montpellier (3) · Central Hospital, Nancy, France (3) · Charite University, Berlin, Germany (2) · Imperial College London (2) · Dr. George Luciuk (2)
What is being tested here
Drugs under test in Anaphylaxis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Epinephrine | 2 | 0 | 10 |
| Dexamethasone | 1 | 0 | 1 |
| cow's milk | 0 | 0 | 2 |
| Peanut | 0 | 0 | 2 |
| Omalizumab | 0 | 0 | 2 |
| Prebiotics | 0 | 0 | 1 |
| KP-001 | 0 | 0 | 1 |
| Chlorpheniramine | 0 | 0 | 1 |
| Ranitidine | 0 | 0 | 1 |
| Acetaminophen | 0 | 0 | 1 |
Drug classes tested here Bronchodilators 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7, phase 3 first
- Apr 2027Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO Study · Phase 3 · Pablo Rodríguez del Rio
- Dec 2026Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral Challenges · Dr. George Luciuk
- Dec 2026Steroid Use in Treatment of Allergic Reactions to Food · Johannes Trueck
- Jan 2027Allergy and Immunology Natural History Study · Columbia University
- May 2027Pharmacokinetics and Safety of a Single Dose of Epinephrine Nasal Spray in Paediatric Allergy Patients · Hikma Pharmaceuticals USA Inc.
- Aug 2027A Registry for the Food Allergy Community · Food Allergy Research & Education
- Oct 2027Tolerance in Beekeepers · University Hospital Plymouth NHS Trust
Who these studies take
Of the 16 Anaphylaxis studies recruiting now, 10 (63%) set no upper age limit and 5 (31%) stop at 75 or younger. 10 (63%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 8 (50%) | 8 (50%) |
| 18 | 14 (88%) | 14 (88%) |
| 30 | 13 (81%) | 13 (81%) |
| 40 | 13 (81%) | 13 (81%) |
| 50 | 13 (81%) | 13 (81%) |
| 65 | 13 (81%) | 13 (81%) |
| 75 | 11 (69%) | 11 (69%) |
| 85 | 11 (69%) | 11 (69%) |
Across all 100 studies, recruiting or not: 52% stop at 75 or younger and 44% at 65; 54% take children; 0% are for women only and 1% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Anaphylaxis studies take
Of 13 interventional studies with no phase under Anaphylaxis, half reached primary completion within 12 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 12 mo6–37 · 13 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Post-market Safety Study of LUMISIGHTOct 14, 2026NCT07572162
Newly registered2
Studies
Recruiting first, then most recently updated. Showing 50 of 100. Browse all 100 → or search them.
- Maximum Lysis on Thromboelastography as a Marker of Systemic Severity in Acute Allergic ReactionsRecruitingNCT079059111 country
- Pharmacokinetics and Safety of a Single Dose of Epinephrine Nasal Spray in Paediatric Allergy PatientsNot yet recruitingNCT07891780Phase 21 country
- Post-market Safety Study of LUMISIGHTRecruitingNCT075721621 country
- Tolerance in BeekeepersRecruitingNCT061560461 country
- Optimizing the Diagnostic Approach to Cephalosporin Allergy TestingRecruitingNCT06406114Phase 21 country
- Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing, Immunotherapy or Oral ChallengesRecruitingNCT07038746Phase 11 country
- FASC: Fish Allergy in Spanish Children - A Study of New Cases of Fish Allergy in Children and AdolescentsNot yet recruitingNCT07727148
- Diagnosis and Allergen Identification of Perioperative AnaphylaxisRecruitingNCT067931631 country
- Comparison Between a Rush and a Conventional Oral Immunotherapy Protocol to Treat Cow's Milk and Hen´s Egg Allergy. CompITO StudyRecruitingNCT06976775Phase 2/31 country
- Allergy and Immunology Natural History StudyRecruitingNCT055844881 country
- Steroid Use in Treatment of Allergic Reactions to FoodRecruitingNCT07341776Phase 41 country
- Analysis of the Role of IgE Proteoforms in Health and DiseaseRecruitingNCT073281781 country
- Comparative PK/PD of FMXIN002 and EpiPen, in Healthy Adults With Allergic RhinitisEnrolling by invitationNCT07228325Phase 1/21 country
- FMXIN002 in Patients at Risk of AnaphylaxisEnrolling by invitationNCT07045701Phase 2/31 country
- A Registry for the Food Allergy CommunityRecruitingNCT046533241 country
- Repertoire and Properties of Anti-drug Antibodies Involved in Immediate Hypersensitivity in the Operating RoomRecruitingNCT05420935Not applicable1 country
- Acquisition and Long-term Observation of Patients With Severe Allergic ReactionsRecruitingNCT052105431 country
- Use of Dexamethasone in Prevention of the Second Phase or a Biphasic Reaction of AnaphylaxisRecruitingNCT03523221Phase 11 country
- Acutelines: a Large Data-/Biobank of Acute and Emergency MedicineRecruitingNCT046150651 country
- GERAP's Epidemiological Survey on Perioperative Hypersensitivity ReactionsRecruitingNCT046549231 country
- Observation Periods and Biphasic Reaction Risk Factors in Pediatric Emergency Anaphylaxis CasesCompletedNCT07231393
- EPAP, InterviewstudyActive, not recruitingNCT061929141 country
- Mechanisms of AnaphylaxisActive, not recruitingNCT031824911 country
- Natural History of Severe Allergic Inflammation and ReactionsCompletedNCT011642411 country
- Cause of Unexplained AnaphylaxisCompletedNCT007197191 country
- Allergy and COVID-19 VaccinesCompletedNCT05028257Phase 31 country
- DEpth of EPinephrine Delivery With Auto-injectors DevicesCompletedNCT02886468Not applicable1 country
- Virtual Reality-Based Simulation Versus High-Fidelity Simulation for Emergency Management Training in Medical InternsActive, not recruitingNCT07584863Not applicable1 country
- PK/PD Study of IN-001 Sublingual Spray in Healthy AdultsCompletedNCT07210320Phase 11 country
- Oral Immunotherapy in Food Allergy in FinlandCompletedNCT02640014Not applicable1 country
- Clinical Determinants and Perioperative Allergic Reactions (CADECAP Study)CompletedNCT039187721 country
- Pinpoint Trial: Prebiotics IN Peanut Oral ImmunoTherapyCompletedNCT05138757Phase 1/21 country
- Accidental Reactions in Peanut/Tree Nut Allergic ChildrenCompletedNCT056714711 country
- Standardised Drug Provocation Testing in Perioperative HypersensitivityCompletedNCT06065137Not applicable1 country
- Phase 1 Crossover Study Evaluating the Safety, Tolerability, and Pharmacokinetics of KP001 in Healthy Adult VolunteersCompletedNCT06963411Phase 11 country
- Predicting Peanut Anaphylaxis and Reducing EpinephrineCompletedNCT05696236Not applicable1 country
- Effects of Inhaled Epinephrine on Systemic Allergic Reactions During Allergy Testing Immunotherapy or Oral ChallengesCompletedNCT06445374Phase 11 country
- Hymenoptera Venom Immunotherapy: Evaluation of Its Long-term Efficacy at the University Hospital of Angers (EFLOTITA2)CompletedNCT053116441 country
- A Study About the Use of Omalizumab in the Treatment of Food Allergy and AnaphylaxisCompletedNCT070271631 country
- Comparative Bioavailability of Intranasal EpinephrineCompletedNCT06205134Phase 1/21 country
- INhaled Salbutamol vs Placebo for the Treatment of Acute IgE-mediated Abdominal Pain From Allergic Food REactionsTerminatedNCT05653024Phase 31 country
- Canadian Anaphylaxis Network- Predicting Recurrence After Emergency Presentation for Allergic REactionActive, not recruitingNCT051353771 country
- Defining ENDOtypes in Perioperative Hypersensitivity by Extensive Cellular and Molecular PHENotyping (ENDOPHEN)CompletedNCT040061061 country
- Study of Inhaled DMC-IH1 and Intramuscular (EpiPen®) Epinephrine in Healthy Male and Female Participants.CompletedNCT06013150Phase 11 country
- Mechanisms of N-acetylcysteine Mediated Vascular Adverse EffectsCompletedNCT01209455Not applicable1 country
- Oral Penicillin Challenge and Allergy De-labeling in ChildrenTerminatedNCT05563610Phase 41 country
- Design, Implementation and Evaluation of the Guided Observer Role in Clinical SimulationCompletedNCT06405399Not applicable1 country
- Omalizumab in Severe Asthmatics With Food AllergyCompletedNCT063164141 country
- Peanut Oral Immunotherapy in Children With Peanut Allergy (Peanut Flour)CompletedNCT02203799Phase 11 country
- Bioavailability of Nasal EpinephrineCompletedNCT04696822Phase 11 country