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CompletedNCT05671471ALLERGYUpdated Dec 26, 2025

Accidental Reactions in Peanut/Tree Nut Allergic Children

An observational study in Peanut and Tree Nut Allergy, sponsored by University Hospital, Lille. Completed at 1 site in France. Open to participants aged Up to 18 Years. Per ClinicalTrials.gov, last updated 2025-12-26.

Sponsored by University Hospital, Lille · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
147
Ages
Up to 18 Years
Sex
All
01

Study summary

Food allergy is an immune reaction, triggered by food protein allergens, of varying severity, from mild local reaction to life threatening anaphylaxis and fatalities.

Peanut is a plant from the botanical family of the Fabaceae, more commonly known as legumes. The prevalence of peanut and tree nut allergy is increasing. In France (ELFE cohort), it is estimated to 0.93%. The tree nuts include mainly almond, hazelnut, pistachio, cashew nut, walnut, pecan nut and Brazil nut. Allergy's prevalence is estimated to 0.54% in children up to 5.5 years. Peanut allergy is a main cause of anaphylaxis and deaths due to food allergy.

Recurrence of food allergy is a main concern. The risk has been estimated to 10% per year for peanut.

In France, Data in real-life on the rate of recurrence of allergic reactions and anaphylaxis to peanut/tree-nut as well as risk factors, are lacking.

The objective of this study is to assess the frequency of allergic reaction to peanut and tree-nuts, to describe the reactions' characteristics and risk factors.

02

Conditions studied

  • Peanut and Tree Nut Allergy

Keywords

  • Peanut allergy
  • tree nut allergy
  • peanut immunotherapy
  • anaphylaxis
  • real life
03

In context

Peanut Hypersensitivity

166 studies on the registry are indexed under Peanut Hypersensitivity; 27 are open to participants now.

This study's enrollment of 147 is below the median of 220 across 30 observational studies indexed under Peanut Hypersensitivity.

Browse Peanut Hypersensitivity studies →

Lead sponsor

University Hospital, Lille is the lead sponsor of 631 studies on the registry; 142 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Up to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients followed in the Pediatric Allergy and Pulmonology Unit, CHU Lille, aged 0-18 years with peanut and/or tree nut allergy

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Confirmed allergy to peanuts and/or nuts

Exclusion criteria

Exclusion Criteria:

  • Other chronic diseases, except allergic comorbidities (asthma, rhinitis, atopic dermatitis, other food allergy)
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
147 participants (actual)
Patient registry
No

Groups and cohorts

  • Allergic Children

    Patients followed in the Pediatric Allergy and Pulmonology Unit, CHU Lille, aged 0-18 years with peanut and/or tree nut allergy

06

What researchers measure

Primary outcomes

  1. the number of episode of allergic reactions in real life

    Time frame: At 1 year

Secondary outcomes

  1. the severity of the allergic reactions according to a validated scale (FASS scale)

    Time frame: At 1 year

  2. interview for the characteristics of the allergic reactions

    the characteristics of the reactions: symptoms, triggering food and quantity, location, emergency kit available, treatment administered, evolution (hospitalization or emergency room)

    Time frame: At 1 year

  3. interview to defined the risks factor associated

    risk factors for reaction: * Other known allergies * Asthma * Atopic dermatitis * Allergic rhinoconjunctivitis * Patient characteristics: sex, age

    Time frame: At 1 year

07

Study locations

1 site
  • Hop Jeanne de Flandre Chu Lille
    Lille, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 26, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05671471
Responsible party
Sponsor
First posted
Jan 4, 2023
Start date
Sep 22, 2021
Primary completion
Oct 10, 2022
Completion
Oct 10, 2022
Last update
Dec 26, 2025

Study contacts

Antoine DESCHILDRE, MD,PhD
principal investigator · University Hospital, Lille

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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