Amyloidosis: all 495 studies
Page 4 of 5. Open to participants first (134), then studies with results posted, then the rest; newest registration first within each.
- A Single Dose Study to Evaluate the Pharmacokinetics of Acoramidis Modified Release Formulations in Healthy SubjectsCompletedNCT04769479Phase 1
- Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral HemorrhageStatus unknownNCT04757597Not applicable
- Unmasking the Prevalence of AC in an Unselected Echocardiographic PopulationStatus unknownNCT04738266
- Effect of Psyllium (Plantago Ovata) on Digestive Disorders in Familial AmyloidosisWithdrawnNCT04695340Not applicable
- Study of Olfactory Disorders in Patients With Cardiac AmyloidosisCompletedNCT04661800Not applicable
- A Study to Investigate the Relationship Between Duration of Treatment and Response in Patients With Multiple Myeloma (MM) or Systemic AL Amyloidosis Treated in Real-life PracticeCompletedNCT04659798
- Cardiac Amyloidosis in Spinal Stenosis: the CASS-studyActive, not recruitingNCT04653675
- Screening to Improve Survival in AL AmyloidosisCompletedNCT04615572
- Comparison of BTD and BCD Based Regimens in the Treatment of AL AmyloidosisStatus unknownNCT04612582Phase 4
- Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release SurgeryTerminatedNCT04611204
- MRI-visible Enlarged Perivascular Spaces and the Alteration of Lymphatic Drainage System in CAAStatus unknownNCT04604587Phase 3
- Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)CompletedNCT04601051Phase 1
- Patient-Reported Outcome Measures in Wild-Type and Variant Cardiac Transthyretin AmyloidosisStatus unknownNCT04563286
- ATTR-Cardiomyopathy Stabilization Following Tafamidis TherapyStatus unknownNCT04513600
- Daratumumab Combined With Bortezomib and Dexamethasone in Mayo 04 Stage III Light Chain AmyloidosisStatus unknownNCT04474938Phase 2
- Cardiac Amyloidosis : Diagnostic Using Red Flag SignalsStatus unknownNCT04459169
- Noninvasive Assessment of Myocardial Stiffness by 2D-SWE Ultrasound Technique (Bidimensional Shear Wave Elastography) in Patients With Transthyretin AmyloidosisStatus unknownNCT04456582Not applicable
- Efficacy and Safety of AG10 in Subjects with Transthyretin Amyloid PolyneurophathyWithdrawnNCT04418024Phase 3
- Novel Imaging Tools in Newly-diagnosed Patients With Cardiac AL AmyloidosisCompletedNCT04392960Not applicable
- Morpho-functional Cardiac Modifications in Treated Mutated Transthyretin Cardiac AmyloidosisStatus unknownNCT04387344
- Targeted Testing for ATTR Among Aortic Stenosis Patients-PilotWithdrawnNCT04363294Not applicable
- First-in-Human Study of NI006 in Patients With Amyloid Transthyretin CardiomyopathyCompletedNCT04360434Phase 1
- Study of the Safety and Efficacy of STI-6129 in Patients With Relapsed or Refractory Systemic AL AmyloidosisStatus unknownNCT04316442Phase 1/2
- Frontline Lenalidomide for AL Amyloidosis Involving MyocardiumCompletedNCT04298372Phase 3
- Carpal Tunnel Syndrome and AmyloidosisStatus unknownNCT04245098Not applicable
- Penn Biobank Return of Research Results ProgramCompletedNCT04242667Not applicable
- A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A MutationCompletedNCT04201418
- Modeling the Relationships Between Functional Connectivity and Amyloid Deposition in Alzheimer's DiseaseStatus unknownNCT04174287Phase 2
- The Potential Role of 18F-NaF PET/CT in Diagnosing Cardiac AmyloidosisStatus unknownNCT04146480Not applicable
- Diagnosis of Cardiac Amyloidosis With 99mTc-PYP; Comparison Between Planar Imaging, SPECT/CT and Cardiac-dedicated CZT CameraStatus unknownNCT04146415Not applicable
- CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)CompletedNCT04136171Phase 3
- A Study of Daratumumab Monotherapy in Previously Untreated Patients With Stage 3B Light Chain (AL) AmyloidosisCompletedNCT04131309Phase 2
- A Clinical Study of Melphalan Flufenamide (Melflufen) and Dexamethasone for Patients With Immunoglobulin Light Chain (AL) AmyloidosisTerminatedNCT04115956Phase 1
- Molecular Imaging of the Underlying Mechanism of Cardiotoxicity in Patients With Light Chain Amyloidosis Using PET/CTTerminatedNCT04105634Early Phase 1
- Application of High Resolution Optical Coherence Tomography in Skin Disease: Amyloidosis and Differential DiagnosisCompletedNCT04068077
- Prevalence of Amyloidosis in Heart Failure (PREVAMIC)Status unknownNCT04066452
- ATTR Amyloidosis in Elderly Patients With Aortic StenosisStatus unknownNCT04061213
- Platelet Reactivity, B-amyloid, MOTS-c and Mortality of Type II Diabetics With CADStatus unknownNCT04027712
- The Diagnostic Value of Hybrid PET/MR for Systemic AmyloidosisStatus unknownNCT04006223
- Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel SyndromeCompletedNCT03996382Not applicable
- Amyloidosis Typing Using Mass Spectrometry-based Proteomics: a New Accurate Tool for Difficult TypingCompletedNCT03984721Not applicable
- Multimodal Biomarkers for Diagnosis and Prognosis in CAAStatus unknownNCT03969732Phase 3
- Prevalence of Wild Type ATTRCompletedNCT03966105
- A Study to Desensitize Allergic Reactions to Treatments for Blood DisordersCompletedNCT03959358Phase 2
- Screening for Systemic Amyloidosis Via the Ligamentum FlavumCompletedNCT03923920
- Facilitating Optimal Routines in AgingCompletedNCT03913637Not applicable
- Cardiac Amyloidosis Screening at Trigger Finger ReleaseCompletedNCT03886155
- Multiple Ascending Dose Study in Healthy SubjectsTerminatedNCT03879278Phase 1
- Prevalence of Wildtype Amyloid After TAVRWithdrawnNCT03825406
- Evaluation of MyoStrain™ in Clinical PracticeCompletedNCT03825224
- Detection of Amyloidosis in Multiple Myeloma Patients by [18F]Florbetaben Positron Emission TomographyCompletedNCT03779815Not applicable
- A Study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) DiseaseTerminatedNCT03774784
- 24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy PatientsTerminatedNCT03702829Phase 2
- 124I-p5+14 Injection Safety in Subjects With Systemic AmyloidosisCompletedNCT03678259Phase 1/2
- PET/MR Imaging In Patients With Cardiac AmyloidosisCompletedNCT03626584
- Assessment of 18F-Florbetaben Whole-body PET for the Detection of Cardiac and Extracardiac Sites of Amyloid DepositsCompletedNCT03616496Not applicable
- A Study of NPT189 in Healthy SubjectsCompletedNCT03610035Phase 1
- Short-term Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR)CompletedNCT03591757Early Phase 1
- Clinical Trial to Assess the Safety of a Novel Scaffold BiomaterialActive, not recruitingNCT03584022Not applicable
- Pro-arrhythmic Potential of GSK3039294 in Healthy SubjectsWithdrawnNCT03567499Phase 1
- Application of Amyloid PET in Cerebral Amyloid AngiopathyCompletedNCT03542656Phase 3
- A Study of Doxycycline and Tauroursodeoxycholic Acid (Doxy/TUDCA) Plus Standard Supportive Therapy Versus Standard Supportive Therapy Alone in Cardiac Amyloidosis Caused by TransthyretinCompletedNCT03481972Phase 3
- A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based TherapyTerminatedNCT03474458Phase 2/3
- Optical Coherence Tomography in Cerebral AmyloidosisStatus unknownNCT03472482
- Monitoring of Early Disease Progression in Hereditary Transthyretin AmyloidosisCompletedNCT03431896
- Transthyretin Cardiac Amyloidosis in HFpEFCompletedNCT03414632Early Phase 1
- BCD With or Without Doxycycline in Mayo Stage II-III Light Chain Amyloidosis PatientsCompletedNCT03401372Not applicable
- ATTR Expanded Access Program (EAP) by IonisApproved for marketingNCT03400098
- Narcolepsy Protect Against Alzheimer's Disease?CompletedNCT03378453Not applicable
- Early Diagnosis of TTR Amyloidosis by Use of Molecular BiologyCompletedNCT03373370
- Positron Emission Tomography / Magnetic Resonance Imaging in Aortic StenosisCompletedNCT03352089
- A Study of PRX004 in Subjects With Amyloid Transthyretin (ATTR) AmyloidosisTerminatedNCT03336580Phase 1
- Mitochondrial Function in Transthyretin AmyloidosisTerminatedNCT03328338
- Frequency of Cardiac Amyloidosis in the Caribbean's. (TEAM Amylose)CompletedNCT03322319Not applicable
- Copper 64Cu-DOTA-Daratumumab Positron Emission Tomography in Diagnosing Patients With Relapsed Multiple MyelomaCompletedNCT03311828Phase 1
- Cerebral Infarction and White Substance in Angiopathy Cerebral AmyloidCompletedNCT03262246
- Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary AmyloidosisStatus unknownNCT03252600Phase 2
- Ixazomib In Combination With Cyclophosphamide And Dexamethasone for Newly Diagnosed AL AmyloidosisCompletedNCT03236792Phase 1/2
- Assessment of Cardiac Fixation During PET Using a New Drug Within Amyloid Cardiac Injuries.TerminatedNCT03232632Early Phase 1
- Comparison of Hemodialysis With Medium Cut-off Dialyzer (Theranova) and High Flux DialyzerCompletedNCT03211676Not applicable
- Use Lay Language. CAA-ri : a Series of 28 PatientsTerminatedNCT03187886
- Ibrutinib With or Without Bortezomib and Dexamethasone in Treating Patients With Relapsed or Refractory Immunoglobulin Light Chain AmyloidosisWithdrawnNCT03130348Phase 2
- Return of Amyloid Imaging Results (RAISR Study)CompletedNCT03121118
- PET/MRI Evaluation of Cardiac AmyloidCompletedNCT03119558Early Phase 1
- Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac DiseaseStatus unknownNCT03098901Not applicable
- The Role of Occult Cardiac Amyloid in the Elderly With Aortic Stenosis.CompletedNCT03029026
- Diagnostic Utility of F-18 Florbetapir PET/MR in Peripheral Nerve AmyloidosisCompletedNCT03019029Phase 1/2
- Trial of Venetoclax (ABT-199) and Dexamethasone for Relapsed or Refractory Systemic AL AmyloidosisTerminatedNCT03000660Phase 1
- Thalidomide/Dexamethasone Treatment And PET Evaluation In Organ Involvemenet of Cardiac AmyloidosisStatus unknownNCT02966522Phase 2
- Risk Evaluation and Education for Alzheimer's Disease - the Study of Communicating Amyloid Neuroimaging (REVEAL-SCAN)CompletedNCT02959489Not applicable
- Phase 1 Study of GSK2315698 in Healthy Japanese SubjectsCompletedNCT02953808Phase 1
- Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)Approved for marketingNCT02939820
- Study of Captisol Enabled Melphalan and Pharmacokinetics for Patients With Multiple Myeloma or Light Chain Amyloidosis That Are Receiving an Autologous Transplant.Active, not recruitingNCT02909036Phase 1
- Daratumumab Therapy for Patients With Refractory or Relapsed AL AmyloidosisCompletedNCT02816476Phase 2
- A Safety and Tolerability Study of an Investigational Drug, ALN-TTRSC02, in Healthy SubjectsCompletedNCT02797847Phase 1
- Carpal Tunnel Syndrome and Amyloid CardiomyopathyCompletedNCT02792790
- Vinorelbine and Gemcitabine in MyelomaCompletedNCT02791373Phase 2
- Ilaris (Canakinumab) in Patient With Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA)Status unknownNCT02775994Phase 1
- A Diagnostic Screening Trial Seeking AL Amyloidosis Very EarlyCompletedNCT02741999
- Assessment of Minimal Residual Disease (MRD) After Antineoplastic Treatment in Patients With AL AmyloidosisCompletedNCT02716103