Amyloidosis: all 495 studies

Page 2 of 5. Open to participants first (135), then studies with results posted, then the rest; newest registration first within each.

• Study of AT-02 in Healthy Volunteers and Subjects With Systemic AmyloidosisRecruitingNCT05521022Phase 1
• Heart Failure: Don't Forget the Role of AmyloidosisRecruitingNCT05501847Not applicable
• Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR CarriersRecruitingNCT05489549
• The Italian Transthyretin Amyloidosis Web-NetworkRecruitingNCT05444920
• Systemic Transthyretin Amyloidosis: Carpal Tunnel Syndrome in a Portuguese PopulationRecruitingNCT05409833
• A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFHRecruitingNCT05283993
• A Registry of Chinese AL Amyloidosis Patients Treated With Subcutaneous or Intravenous DaratumumabRecruitingNCT05277493
• Cardiac Amyloidosis Registry StudyEnrolling by invitationNCT05174338
• Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL AmyloidosisRecruitingNCT05145816Phase 1/2
• Registre HEAR, Healthcare European Amyloidosis RegistryRecruitingNCT05101304
• Isatuximab Plus Pomalidomide and Dexamethasone Association for Patients With AL Amyloidosis Not in VGPR or Better After Any Previous TherapyRecruitingNCT05066607Phase 2
• Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance ProgramRecruitingNCT05040373
• Minimal Residual Disease Response-adapted Deferral of Transplant in Dysproteinemia (MILESTONE)RecruitingNCT04991103Phase 2
• Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral NeuropathyNot yet recruitingNCT04985734Not applicable
• APG-2575 in Combination With Novel Therapeutic Regimens in Subjects With Relapsed or Refractory Multiple MyelomaRecruitingNCT04942067Phase 1/2
• Clinical Study of ATTR-CMRecruitingNCT04935021Phase 4
• Clinical Study for AL-CMRecruitingNCT04924998
• Prevalence and Prognosis of Cardiac Amiloidosis in TurkeyRecruitingNCT04915235
• Prevalence Study of Amyloidosis in Patients With Surgery of Suspect Bilateral Carpal Tunnel (AMYLYONCARP)RecruitingNCT04890119Not applicable
• A Registry of AL Amyloidosis (ReAL)RecruitingNCT04839003
• Swiss Cardiac Amyloidosis REgistry (Swiss-CARE)RecruitingNCT04776824
• Amyloid Proteins From Medullary Thyroid Cancer and Laryngeal AmyloidosisNot yet recruitingNCT04760171
• Prevalence and Significance of ATTR Aortic Valve Amyloidosis in Degenerative Aortic StenosisRecruitingNCT04636684Not applicable
• Cardiac Amyloidosis in HFpEFRecruitingNCT04587648
• ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)RecruitingNCT04561518
• Quantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR AmyloidosisRecruitingNCT04535349Not applicable
• DZHK TORCH-Plus is a Registry for Patients With Cardiomyopathies and Serves as Source for Cardiovascular Research StudiesRecruitingNCT04265040
• Identification of Prognostic Parameters in Patients With " Senile " Amyloid CardiomyopathyRecruitingNCT04225754
• Autologous Stem Cell Transplantation for Patients With AL AmyloidosisEnrolling by invitationNCT04210791
• Registry for Adults With Plasma Cell Disorders (PCD's)RecruitingNCT03717844
• Sahlgrenska Cardiomyopathy ProjectEnrolling by invitationNCT03527342
• Effect of Radiotherapy on ATTR Cardiac Amyloidosis : a Proof of Concept StudyRecruitingNCT03397810Not applicable
• Expanded Access to VenetoclaxAvailableNCT03123029
• Physiologic Assessment of Microvascular Function in Patients With Cardiac AmyloidosisRecruitingNCT02798705
• Molecular Imaging of Primary Amyloid CardiomyopathyRecruitingNCT02641145Not applicable
• Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.CompletedNCT05560555Results posted
• A Study to Evaluate Organ Level Uptake Repeatability of 124I AT-01 in Subjects With Systemic AmyloidosisCompletedNCT05235269Phase 2Results posted
• SGLT2 Inhibitors in Transthyretin Amyloid CardiomyopathyCompletedNCT05233163Phase 4Results posted
• A Study to Examine the Clinical Effectiveness of Tafamidis in Patients With Mixed Phenotype Hereditary Transthyretin AmyloidosisCompletedNCT05139680Results posted
• COVID-19 VAX Booster Dosing in Patients With Hematologic MalignanciesCompletedNCT05028374Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL AmyloidosisTerminatedNCT04973137Phase 3Results posted
• The Effect Of Tafamidis Meglumine In Transthyretin Amyloid Polyneuropathy PatientsCompletedNCT04828993Phase 4Results posted
• A Study to Assess the Safety and Efficacy Of Tafamidis In Chinese Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)CompletedNCT04814186Phase 4Results posted
• Global Prevalence of ATTR-CM in Participants With HFpEFTerminatedNCT04424914Not applicableResults posted
• Long-term Monitoring of Patients With Cardiac Amyloidosis With Implantable Event MonitorsCompletedNCT04421040Not applicableResults posted
• A Study to Characterize Adverse Events Occurring Within One Day of TEGSEDI Administration to Adult Participants With hATTR-PNTerminatedNCT04306510Phase 4Results posted
• A Study to Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL AmyloidosisCompletedNCT04304144Phase 2Results posted
• HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyActive, not recruitingNCT04153149Phase 3Results posted
• NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Hereditary Transthyretin-Mediated Amyloid PolyneuropathyCompletedNCT04136184Phase 3Results posted
• APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)CompletedNCT03997383Phase 3Results posted
• Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver TransplantCompletedNCT03862807Phase 3Results posted
• Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid CardiomyopathyCompletedNCT03860935Phase 3Results posted
• Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown EtiologyCompletedNCT03842163Results posted
• Evaluate the Safety and Tolerability, as Well as the Pharmacokinetic and Pharmacodynamic Profiles of Single and Multiple Doses of Eplontersen Administered Subcutaneously to Healthy Volunteers and Patients With Hereditary Transthyretin-Mediated Amyloidosis (hATTR ).CompletedNCT03728634Phase 1/2Results posted
• Open-Label Study of AG10 in Patients With CardiomyopathyTerminatedNCT03536767Phase 2Results posted
• Biodistribution of 89Zirconium-labelled GSK2398852 Using PET ImagingTerminatedNCT03417830Phase 1Results posted
• A Study to Evaluate the Efficacy and Safety of Daratumumab in Combination With Cyclophosphamide, Bortezomib and Dexamethasone (CyBorD) Compared to CyBorD Alone in Newly Diagnosed Systemic Amyloid Light-chain (AL) AmyloidosisCompletedNCT03201965Phase 3Results posted
• Renal AL Amyloid Involvement and NEOD001TerminatedNCT03168906Phase 2Results posted
• Study in Subjects With Light Chain (AL) AmyloidosisTerminatedNCT03154047Phase 2Results posted
• Sleep Quality and Amyloid-Beta KineticsCompletedNCT03077620Not applicableResults posted
• Multiple Treatment Session Study to Assess GSK2398852 Administered Following and Along With GSK2315698TerminatedNCT03044353Phase 2Results posted
• The Role of F-18 Florbetapir in the Early Detection of Cardiac AmyloidosisTerminatedNCT03040427Phase 4Results posted
• Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis PatientsTerminatedNCT02994784Phase 2Results posted
• Ixazomib Rollover StudyCompletedNCT02924272Phase 2Results posted
• An Extention Study of Safety of Canakinumab in Japanese Patients With Periodic Fever SyndromesCompletedNCT02911857Phase 3Results posted
• Daratumumab for the Treatment of Patients With AL AmyloidosisCompletedNCT02841033Phase 1/2Results posted
• Low Dose RT to Reduce Cerebral Amyloidosis in Early Alzheimer'sTerminatedNCT02769000Not applicableResults posted
• The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) AmyloidosisCompletedNCT02632786Phase 2Results posted
• Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) AmyloidosisTerminatedNCT02613182Phase 2Results posted
• A Safety Study of GSK3039294 in Healthy Volunteers and Patients With Systemic AmyloidosisTerminatedNCT02603172Phase 1Results posted
• The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver TransplantCompletedNCT02595983Phase 2Results posted
• Idelalisib for Immunoglobulin M (IgM)-Associated Primary (AL) AmyloidosisTerminatedNCT02590588Phase 2Results posted
• A Dose Escalation Study of Carfilzomib Taken With Thalidomide and Dexamethasone in Relapsed AL AmyloidosisCompletedNCT02545907Phase 1/2Results posted
• The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran)CompletedNCT02510261Phase 3Results posted
• Trial of High Dose Melphalan/Stem Cell Transplant With or Without BortezomibTerminatedNCT02489500Phase 3Results posted
• A Study of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis or Hereditary Periodic Fevers Who Participated in the CACZ885G2301E1, CACZ885G2306 or CACZ885N2301 StudiesCompletedNCT02334748Phase 3Results posted
• ENDEAVOUR: Phase 3 Multicenter Study of Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Mediated Familial Amyloidotic Cardiomyopathy (FAC)CompletedNCT02319005Phase 3Results posted
• The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL AmyloidosisTerminatedNCT02312206Phase 3Results posted
• A Extension Study to Evaluate Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Cardiac AmyloidosisCompletedNCT02292186Phase 2Results posted
• Doxycycline to Upgrade Organ Response in Light Chain (AL) Amyloidosis TrialCompletedNCT02207556Phase 2Results posted
• Extension Study Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)CompletedNCT02175004Phase 3Results posted
• Escitalopram Effects on CSF Amyloid BetaCompletedNCT02161458Phase 4Results posted
• Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal DiseaseCompletedNCT02158052Not applicableResults posted
• Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep InductionCompletedNCT02063217Not applicableResults posted
• Study of Efficacy and Safety of Canakinumab in Patients With Hereditary Periodic FeversCompletedNCT02059291Phase 3Results posted
• The Study of ALN-TTR02 (Patisiran) for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran)CompletedNCT01961921Phase 2Results posted
• APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated AmyloidosisCompletedNCT01960348Phase 3Results posted
• Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain AmyloidosisCompletedNCT01864018Phase 1/2Results posted
• Doxycycline and TUDCA in Patients With Transthyretin Amyloid CardiomyopathyCompletedNCT01855360Phase 1/2Results posted
• Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple MyelomaCompletedNCT01849783Phase 2Results posted
• Study Evaluating the Safety,Tolerability and Efficacy of PF-04360365 in Adults With Probable Cerebral Amyloid AngiopathyCompletedNCT01821118Phase 2Results posted
• Efficacy and Safety of Inotersen in Familial Amyloid PolyneuropathyCompletedNCT01737398Phase 2/3Results posted
• Imaging Cardiac Amyloidosis: A Pilot Study Using F-18 Florbetapir Positron Emission TomographyCompletedNCT01683825Phase 4Results posted
• Safety and Effect of Doxycycline in Patients With AmyloidosisCompletedNCT01677286Phase 2Results posted
• Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) AmyloidosisTerminatedNCT01659658Phase 3Results posted
• Safety and Tolerability of Patisiran (ALN-TTR02) in Transthyretin (TTR) AmyloidosisCompletedNCT01617967Phase 2Results posted
• Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And CaregiversCompletedNCT01604122Results posted
• A Phase I/II Trial of Pomalidomide and Dexamethasone in Subjects With Previously-Treated AL AmyloidosisCompletedNCT01570387Phase 1/2Results posted
• The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M TransthyretinCompletedNCT01435655Phase 3Results posted
• Bortezomib/Dexamethasone (BD), Followed By Autologous Stem Cell Transplantation and Maintenance Bortezomib/Dexamethasone For the Initial Treatment of Monoclonal Immunoglobulin Deposition Disease (MIDD) Associated With Multiple Myeloma and AL AmyloidosisCompletedNCT01383759Not applicableResults posted

← Amyloidosis overview