An interventional study of Juniper Aromatherapy and Thyme Aromatherapy in Exam-induced Psychological Stress, Emotional Intelligence and Physiological Stress Responses in Healthy University Students, sponsored by Gulbahar Boyuk Ozcan. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-06.
Sponsored by Gulbahar Boyuk Ozcan · Not applicable, Interventional, and Treatment
Among 39 studies in Stress, Psychological with a site in Turkey — 9 open to participants now, 12 under way, none of them phase 3. Stress, Psychological · Turkey.
Among the 39 studies in Stress, Psychological with a site in Turkey, this one is the 15th largest by enrollment of the 33 interventional ones that give a count, is one of 7 that started in 2024, is one of 33 with no phase, and was the 20th registered.
848 studies on the registry are indexed under Stress, Psychological; 139 are open to participants now.
Browse Stress, Psychological studies →9 of the 39 studies in Stress, Psychological with a site in Turkey are open now. Recruiting first, the newest first:
Istanbul University · Sites in Turkey
Ages 18+
Mustafa Kemal University · Sites in Turkey
Ages 20–30 · Healthy volunteers
Fidan Balkaya · Sites in Turkey
Ages 18+ · Women only · Healthy volunteers
Süleyman Korkusuz · Sites in Turkey
Healthy volunteers
Kilis 7 Aralik University · Sites in Turkey
Ages 0 days–28 days · Healthy volunteers
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 75 Stress, Psychological studies recruiting now, 34 (45%) set no upper age limit and 37 (49%) stop at 75 or younger; 14 take children under 18; 49 take healthy volunteers.
This study: 18 Years to 25 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
39 studies; the count open now beside each. This study's row is marked.
First in 2018; this study’s year is marked. 7 started in 2024.
This study's enrollment of 94 is above the median of 84 across 692 interventional studies indexed under Stress, Psychological.
Median enrollment 80 across the 33 interventional studies, 72 across the 6 observational. Of the 27 that completed or were terminated, 0 (0%) have results posted.
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None of the 39 has an industry lead sponsor. The 10 most frequent:
Gulbahar Boyuk Ozcan is the lead sponsor of 2 studies on the registry; none are open to participants now.
Gulbahar Boyuk Ozcan has 2 studies filed under Stress, Psychological — fewer than ten, so there is no comparison to draw.
5 of the studies in Stress, Psychological with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07727434Istanbul UniversityStress and Anxiety Before Biopsy, After Biopsy Results, and During Treatment in Patients With Suspected Bone or Soft Tissue Cancer | 2026-12-20 |
| NCT07906743Fidan BalkayaMandala Coloring in Late Pregnancy | 2027-01-05 |
| NCT07842744Süleyman KorkusuzMultiple Sclerosis Severity and Caregiver Health Outcomes | 2027-01-20 |
| NCT07644949Istanbul Medeniyet UniversitySelf-Help Plus (SH+) for Stress Reduction in Social Service Workers: A Pilot RCT | 2027-02 |
| NCT07666594Tugba Civi KaraaslanMobile App-Based Yoga and Meditation in Rheumatoid Arthritis | 2027-05 |
Add all 5 to your calendar (.ics) → With an account.
Among the 39 studies in Stress, Psychological with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study is an interventional investigation aiming to evaluate the physiological effects of thyme (Thymus vulgaris) and juniper (Juniperus communis) essential oil aroma inhalation on examination stress in medical students. The research assesses participants' emotional intelligence and exam anxiety levels, and analyzes changes in salivary apelin, BDNF, and GRP78 levels using the ELISA method before and after the aromatherapy intervention.
Study Purpose: This study aims to investigate the effects of aroma inhalations (thyme and juniper) on exam stress, adipokines (apelin), neurotrophic factors (BDNF), and endoplasmic reticulum stress responses (GRP78) based on emotional intelligence and exam anxiety levels in medical students. Methods: The study is a three-arm, randomized, controlled interventional investigation conducted on healthy volunteer medical students. Saliva samples are collected before inhalation and immediately after the 15-minute intervention. The ELISA technique is utilized to determine salivary apelin, BDNF, and GRP78 levels.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Being willing to participate in the research, being a medical student, not having a cardiovascular disease, not having any allergies to odors, not being pregnant, not having any respiratory system diseases (such as asthma, , etc.), not having any condition that prevents smelling, not using any medication that affects heart rate and blood pressure, and not having any psychiatric illness.
Exclusion Criteria:
The communication barrier, incomplete filling of forms, menstruation in girls, allergy to the scents of thyme and juniper oil, and the occurrence of any side effects during the application.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants inhale juniper essential oil for 40 minutes during the exam. Physiological and hormonal measurements are taken before and after inhalation.
Other: Juniper Aromatherapy
Participants inhale thyme essential oil for 40 minutes during the exam. Physiological and hormonal measurements are taken before and after inhalation.
Other: Thyme Aromatherapy
Participants inhale juniper essential oil (2 drops) via a diffuser or inhaler for approximately 40 minutes during the exam session. This inhalation is intended to assess effects on anxiety-related physiological and hormonal parameters.
Participants inhale thyme essential oil (2 drops) via a diffuser or inhaler for approximately 40 minutes during the exam session. This inhalation is intended to assess effects on anxiety-related physiological and hormonal parameters.
Change in Salivary Apelin Levels
Salivary apelin levels will be measured to evaluate the metabolic and neuroendocrine response to aroma inhalation.
Time frame: Immediately before inhalation and immediately after the 15-minute inhalation intervention
Change in Salivary BDNF Levels
Salivary BDNF levels will be measured as a neurotrophic and physiological stress indicator.
Time frame: Immediately before inhalation and immediately after the 15-minute inhalation intervention
Change in Salivary GRP78 Levels
Salivary GRP78 levels will be measured to monitor cellular endoplasmic reticulum stress responses.
Time frame: Immediately before inhalation and immediately after the 15-minute inhalation intervention
Plan to share: No — The individual participant data (IPD) will not be shared due to ethical considerations and institutional restrictions.
No publications or documents are linked to this record.
Ran from Jun 2024 to primary completion in Jun 2024, 0 months.
Of 459 non-industry interventional studies with no phase under Stress, Psychological, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 26. This study's 0 months is below that.
Counting every sponsor, half of 472 studies reached it within 13 months; a quarter within 5 and three quarters within 26.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Gulbahar Boyuk Ozcan