ClinicalTrials.gg
Not yet recruitingNCT07753980Updated Aug 10, 2026

Presentations and Outcomes of Acute Pancreatitis

An observational study in Acute Pancreatitis, sponsored by Assiut University. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-10.

Sponsored by Assiut University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 12 studies in Pancreatitis by Assiut University — 6 open to participants now, 6 under way, none of them phase 3. Pancreatitis · Assiut University.

Planned enrollment
3rd of 11
100 · median 100
Started
2026
with 1 other
Observational
7 of 12
4 open now
Registered
11th of 12
by date

Among the 12 studies in Pancreatitis by Assiut University, this one is the 3rd largest by planned enrollment of the 11 observational ones, is one of 2 that started in 2026, is one of 7 observational ones, and was the 11th registered.

By phase

12 studies; the count open now beside each. This study's row is marked.

Observationalthis study7 · 4 open
Other kind4 · 2 open
Phase 21 · 0 open

By the year they started

First in 2015; this study’s year is marked. 2 started in 2026.

Size and results

Median enrollment 90 across the 1 interventional studies, 100 across the 11 observational. Of the 2 that completed or were terminated, 0 (0%) have results posted.

Watch this landscapeDownload CSVWith an account: a weekly mail of what changed among 12 studies in Pancreatitis by Assiut University, or all of them as a file.
02

Study summary

Evaluate the outcomes of the patients and their possible predictors.

Read the detailed description

Acute pancreatitis (AP) is an acute inflammatory disease of the pancreas characterized by variable involvement of regional tissues and distant organ systems. The disease may range from mild interstitial edema to severe pancreatic necrosis associated with multiple organ failure and high mortality rates [1,2]. Acute pancreatitis is considered one of the leading gastrointestinal causes of hospital admission worldwide and its incidence has progressively increased over recent decades [3]. The pathogenesis of acute pancreatitis is mainly related to premature activation of pancreatic digestive enzymes within pancreatic acinar cells, resulting in autodigestion of pancreatic tissue and activation of inflammatory pathways [1]. This inflammatory response may progress to systemic inflammatory response syndrome (SIRS), acute respiratory distress syndrome (ARDS), renal failure, shock, and multiorgan dysfunction syndrome (MODS) in severe cases[ 2,4]. Although approximately 80% of patients experience mild self-limited disease with favorable outcomes, nearly 20% develop severe acute pancreatitis associated with pancreatic necrosis, infected collections, persistent organ failure, and systemic complications [3,8]. The overall mortality rate of acute pancreatitis ranges from 3% to 10%, while mortality in severe acute pancreatitis may reach 20-30%, particularly in patients with infected pancreatic necrosis and persistent organ failure4 and [8].Early identification of severe disease and accurate assessment of prognosis are therefore essential to improve patient outcomes and reduce morbidity and mortality [7,8]. In Upper Egypt, particularly at Al-Rajhi University Hospital, prospective data regarding the clinical presentation, etiological factors, disease severity, complications, and outcomes of patients admitted with acute pancreatitis remain limited. In addition, the association between demographic characteristics, comorbidities, severity scores, and short-term clinical outcomes has not been adequately evaluated in the local population.

Accordingly, this prospective study aims to describe the clinical characteristics of hospitalized patients with acute pancreatitis, identify factors associated with adverse outcomes, and evaluate the prognostic value of the Ranson and APACHE II scoring systems. The findings may contribute to improved early risk stratification, support clinical decision-making, optimize resource utilization, and ultimately enhance patient care at Al-Rajhi University Hospital.

03

Conditions studied

  • Acute Pancreatitis

Browse trials for

Keywords

  • acute pancreatitis
  • Al-Rajhi University Hospital
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All enrolled patients will undergo:

  • Detailed medical history taking including demographic data, comorbidities, smoking, alcohol intake, and possible etiological factors.
  • Complete clinical examination.
  • Laboratory investigations including CBC, liver function tests, kidney function tests, serum amylase, serum lipase, calcium profile, lipid profile, and CRP.
  • Radiological investigations including abdominal ultrasonography and CT abdomen when indicated.
  • Assessment of severity using Ranson score, APACHE II score and Revised Atlanta classification.
  • Follow-up during admission for complications, ICU admission, length of hospital stay, and mortality.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 1. Adult patients aged 18 years or older. 2. Patients fulfilling at least two diagnostic criteria of acute pancreatitis. 3. Patients willing to participate in the study.

Exclusion criteria

Exclusion Criteria:

  1. Patients with chronic pancreatitis.
  2. Patients diagnosed with pancreatic .
  3. Patients less than 18 years old.
  4. Patients with incomplete clinical data.
  5. Refusal to participate. -
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No

Interventions

  • OtherUS,MSCT abdomen,arterial blood gases

    arterial blood gases

06

What researchers measure

Primary outcomes

  1. Frequency and types of clinical patterns of acute pancreatitis and the fates of patients.

    Time frame: july 2026-july 2027

07

Study locations

No study locations are listed for this record.

08

References and documents

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07753980
Lead sponsor
Assiut University
Responsible party
Roaa Khaled Mohamed Hasanin (doctor, Assiut University) — Principal investigator
First posted
Aug 10, 2026
Start date
Sep 2026 (estimated)
Primary completion
Sep 2027 (estimated)
Completion
Oct 2027 (estimated)
Last update
Aug 10, 2026

Study contacts

Roaa M Khaled Hasanin, Resident doctor
Contact
ro2a5aled12@gmail.com
00201008753743
Madiha M El attar, professor
Contact
Melattarmakhlouf@aun.edu.eg
00201005207841
Rasha H shehata, assistant professor
study director · Assiut University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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