An observational study in Benign Prostatic Hyperplasia, sponsored by Hitit University. Not yet recruiting at 1 site in Turkey (Türkiye). Open to male participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-06-26.
Sponsored by Hitit University · Observational
Among 39 studies in Prostatic Hyperplasia with a site in Turkey — 14 open to participants now, 15 under way, none of them phase 3. Prostatic Hyperplasia · Turkey.
Among the 39 studies in Prostatic Hyperplasia with a site in Turkey, this one is the 14th largest by planned enrollment of the 20 observational ones that give a count, is one of 11 that started in 2026, is one of 20 observational ones, reaches primary completion later than 6 of the 14 other live ones, and was the 36th registered.
827 studies on the registry are indexed under Prostatic Hyperplasia; 179 are open to participants now.
Browse Prostatic Hyperplasia studies →14 of the 39 studies in Prostatic Hyperplasia with a site in Turkey are open now. Recruiting first, the newest first:
Hitit University · Sites in Turkey
Ankara City Hospital Bilkent · Sites in Turkey
Eskişehir Osmangazi University Medicine Faculty Hospital · Sites in Turkey
Ankara Training and Research Hospital · Sites in Turkey
inTumo Therapeutics, Inc. · Sites in Turkey
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 102 Prostatic Hyperplasia studies recruiting now, 70 (69%) set no upper age limit and 4 (4%) stop at 75 or younger; 7 take children under 18; 7 take healthy volunteers.
This study: 50 Years and older · male · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
39 studies; the count open now beside each. This study's row is marked.
First in 2003; this study’s year is marked. 11 started in 2026.
This study's planned enrollment of 80 is below the median of 250 across 177 observational studies indexed under Prostatic Hyperplasia.
Median enrollment 85 across the 19 interventional studies, 200 across the 20 observational. Of the 18 that completed or were terminated, 2 (11%) have results posted.
This tab as a report to print or save as PDF → With an account.
3 of 39 have an industry lead sponsor. The 10 most frequent:
Hitit University is the lead sponsor of 87 studies on the registry; 29 are open to participants now.
Hitit University has 2 studies filed under Prostatic Hyperplasia — fewer than ten, so there is no comparison to draw.
6 of the studies in Prostatic Hyperplasia with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07417449Ankara City Hospital BilkentImpact of Long-term Dutasteride Use on Perioperative Outcomes of HoLEP | 2026-11-30 |
| NCT07778355Ondokuz Mayıs UniversityOrientation Video Training Administered at Different Times to Patients Undergoing Prostate Surgery on Postoperative Pain and Anxiety (Video Training) | 2027-03-01 |
| NCT07554989Taksim Egitim ve Arastirma HastanesiComparison of Concurrent Endoscopic Prostate Surgery With Botox-A Injection and Postoperative Medical Therapy in BPH Patients With Overactive Bladder Symptoms | 2027-04-01 |
| NCT07663097Hitit UniversityPreoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia | 2027-04-08 |
| NCT07585552Ondokuz Mayıs UniversityAnesthesia Type and HoLEP Outcomes: A Multi-Center Study | 2027-08-01 |
Among the 39 studies in Prostatic Hyperplasia with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life. Surgical treatment with Holmium Laser Enucleation of the Prostate (HoLEP) or Transurethral Resection of the Prostate (TURP) is often recommended when medical therapy is insufficient.
This prospective observational study aims to evaluate whether preoperative anxiety, depression, and surgical fear influence postoperative functional outcomes, urinary continence, erectile function, and patient satisfaction in patients undergoing HoLEP or TURP for BPH. Participants will complete validated psychological and functional questionnaires before surgery and during postoperative follow-up visits at 1 and 3 months. The study will also assess changes in psychological status after surgery and compare outcomes between HoLEP and TURP patients.
The findings may help improve preoperative patient counseling and identify patients who could benefit from additional psychological support before surgery.
Benign prostatic hyperplasia (BPH) is one of the most common urological conditions affecting aging men and is frequently associated with lower urinary tract symptoms (LUTS) that significantly impair quality of life. Although medical therapy is the first-line treatment for most patients, surgical intervention becomes necessary in cases with severe symptoms, complications, or inadequate response to medication. Transurethral Resection of the Prostate (TURP) has long been considered the standard surgical treatment, while Holmium Laser Enucleation of the Prostate (HoLEP) has emerged as an effective minimally invasive alternative with favorable perioperative and functional outcomes.
Psychological factors such as anxiety, depression, and fear of surgery have been shown to influence recovery, pain perception, treatment satisfaction, and functional outcomes after various surgical procedures. However, the impact of preoperative psychological status on postoperative outcomes in patients undergoing surgery for BPH remains insufficiently investigated.
This prospective, single-center, observational study aims to evaluate the relationship between preoperative anxiety, depression, and surgical fear and postoperative functional outcomes in patients undergoing HoLEP or TURP for BPH. Eighty patients scheduled for surgical treatment of BPH will be enrolled. Patients will be allocated to HoLEP or TURP according to routine clinical practice, surgeon preference, and patient choice. No randomization or study-related intervention will be performed.
Before surgery, participants will complete validated questionnaires assessing lower urinary tract symptoms, erectile function, anxiety, depression, and surgical fear, including the International Prostate Symptom Score (IPSS), International Index of Erectile Function-5 (IIEF-5), State-Trait Anxiety Inventory (STAI), Hospital Anxiety and Depression Scale (HADS), and Surgical Fear Questionnaire (SFQ).
Follow-up assessments will be conducted at postoperative 1 month and 3 months. Functional outcomes, urinary continence, erectile function, psychological status, and patient satisfaction will be evaluated using the same validated instruments. Urinary continence will additionally be assessed using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF).
The primary objective is to determine whether preoperative anxiety levels are associated with postoperative functional improvement, measured by changes in IPSS scores. Secondary objectives include evaluating the relationship between psychological status and postoperative urinary incontinence, erectile function, patient satisfaction, and longitudinal changes in anxiety and depression after surgery. Outcomes will also be compared between patients undergoing HoLEP and TURP.
The results of this study may improve understanding of the role of psychological factors in BPH surgery and contribute to the development of targeted perioperative counseling and psychological support strategies for patients undergoing surgical treatment for BPH.
Male patients aged 50 years or older with benign prostatic hyperplasia (BPH) who are scheduled to undergo Holmium Laser Enucleation of the Prostate (HoLEP) or Transurethral Resection of the Prostate (TURP) at Hitit University Erol Olcok Training and Research Hospital and who provide written informed consent.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients with benign prostatic hyperplasia undergoing HoLEP surgery.
Procedure: Holmium Laser Enucleation of the Prostate (HoLEP)
Patients with benign prostatic hyperplasia undergoing TURP surgery.
Procedure: Transurethral Resection of the Prostate (TURP)
Standard HoLEP procedure for treatment of benign prostatic hyperplasia.
Standard TURP procedure for treatment of benign prostatic hyperplasia.
Change in International Prostate Symptom Score (IPSS)
Association between preoperative anxiety levels and postoperative functional improvement measured by changes in International Prostate Symptom Score (IPSS). IPSS scores range from 0 to 35, with higher scores indicating more severe lower urinary tract symptoms. Change from baseline to postoperative 3 months will be evaluated.
Time frame: Baseline to 3 months after surgery
Change in IIEF-5 Score
Change in International Index of Erectile Function-5 (IIEF-5) score. Scores range from 5 to 25, with higher scores indicating better erectile function.
Time frame: Baseline to 3 months after surgery
Urinary Incontinence Assessed by ICIQ-SF
Urinary continence assessed using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF). Scores range from 0 to 21, with higher scores indicating more severe urinary incontinence.
Time frame: 1 and 3 months after surgery
Change in HADS Score
Change in Hospital Anxiety and Depression Scale (HADS) score. Total scores range from 0 to 42, with higher scores indicating greater anxiety and depressive symptoms.
Time frame: Baseline to 3 months after surgery
Change in STAI Score
Change in State-Trait Anxiety Inventory (STAI) score. Scores range from 20 to 80, with higher scores indicating greater anxiety levels.
Time frame: Baseline to 3 months after surgery
Patient Satisfaction Score
Patient satisfaction will be assessed using a visual analog scale ranging from 0 to 10, with higher scores indicating greater satisfaction with surgical outcomes.
Time frame: 3 months after surgery
Plan to share: No — Individual participant data collected during this study will not be made publicly available due to privacy and confidentiality considerations.
No publications or documents are linked to this record.
Start is estimated for Jun 2026; primary completion for Apr 2027, 9 months later.
Of 59 non-industry observational studies under Prostatic Hyperplasia, half reached primary completion within 33 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 50. This study's planned 9 months is below that.
Counting every sponsor, half of 74 studies reached it within 25 months; a quarter within 12 and three quarters within 50.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Hitit University