An interventional study of surgery in Cleft Lip, Nose; Anomaly and Repair, sponsored by King Edward Medical University. Completed at 1 site in Pakistan. Per ClinicalTrials.gov, last updated 2026-06-03.
Sponsored by King Edward Medical University · Not applicable, Interventional, and Treatment
Dermal Roll flap for alar base support
Background: Unilateral secondary cleft lip and nasal deformity is almost always associated with under projected cleft side alar base for which augmentation with autologous grafts or synthetic material has been described. Many of such cases with secondary cleft lip and nasal deformity require revision surgery for wide lip scar or vermillion disparities. Objective: During lip revision surgery, some vascularized lip tissue can be spared in the area of previous repair and can be utilized as dermal roll flap for augmentation of alar base. Methodology: This prospective study was conducted on forty-three patients requiring lip scar revision with unilateral secondary cleft lip and nasal deformity having difference of alar base projection of 2 to 5mm measured on basal view photograph. Dermal roll flap was marked, de-epithelized and incised. Tunnel under the alar base was made, insetting of flap was done and lip repair completed. Measurements repeated after 6 months to find out improvement in the projection.
162 studies on the registry are indexed under Cleft Lip; 51 are open to participants now.
This study's enrollment of 45 is above the median of 30 across 114 interventional studies indexed under Cleft Lip.
Browse Cleft Lip studies →King Edward Medical University is the lead sponsor of 78 studies on the registry; 24 are open to participants now.
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Exclusion Criteria:
Patients with Secondary cleft lip and nasal deformity
Procedure: surgery
Dermal Roll flap from the lip to support alar base
Alar base projection
Pre and post operative alar base projection will be measured by by drawing horizontal line extending from normal alar base towards columella and crossing towards to cleft side alar base making perpendicular to the vertical line passing through the height of columella. Difference of cleft side alar base projection will be determined by measuring the distance of alar base central point from the horizontal line.
Time frame: 6 months
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Plan to share: No
This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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King Edward Medical University