ClinicalTrials.gg
CompletedNCT07478692Updated Mar 17, 2026

Effects of Transversus Abdominis Plane Block on Recovery Quality and Maternal-Neonatal Outcomes After Cesarean Delivery

An interventional study of The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg) in Postoperative Pain After Cesarean Section, sponsored by Qing Yuan. Completed at 2 sites in China. Open to female participants aged 20 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-17.

Sponsored by Qing Yuan · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Registered 9 months after the study started (first participant enrolled Jun 2025, registered Mar 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
83
Allocation
Randomized
Ages
20 Years to 40 Years
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 248 studies in Pain, Postoperative with a site in China — 78 open to participants now, 80 under way, 3 of them phase 3. Pain, Postoperative · China.

Enrollment
157th of 205
83 · median 132
Started
2025
with 28 others
No phase
103 of 248
36 open now
Registered
223rd of 248
by date

Among the 248 studies in Pain, Postoperative with a site in China, this one is the 157th largest by enrollment of the 205 interventional ones that give a count, is one of 29 that started in 2025, is one of 103 with no phase, and was the 223rd registered.

Pain, Postoperative

5,644 studies on the registry are indexed under Pain, Postoperative; 1,229 are open to participants now.

Browse Pain, Postoperative studies →

Open to participants now

78 of the 248 studies in Pain, Postoperative with a site in China are open now. Recruiting first, the newest first:

73 more — sign in →

All 78 open studies →

A study can be open while its sites in China have not opened yet or have stopped. Only those recruiting at a site in China →

Who these studies take

Of the 678 Pain, Postoperative studies recruiting now, 241 (36%) set no upper age limit and 328 (48%) stop at 75 or younger; 74 take children under 18; 128 take healthy volunteers.

This study: 20 Years to 40 Years · female · healthy volunteers too.

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02

Study summary

ltrasound-guided transversus abdominis plane (TAP) block is an emerging local anesthesia technique that effectively alleviates postoperative pain by injecting anesthetic drugs around the nerves in the abdominal wall. Compared with traditional analgesic methods, TAP blockade may have better analgesic effects and fewer side effects. However, current research on the application of TAP blockade after cesarean section is still limited. Therefore, this study will systematically evaluate its actual effectiveness in pain management after cesarean section through a prospective randomized controlled trial

03

Conditions studied

  • Postoperative Pain After Cesarean Section

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04

Who can participate

Ages eligible
20 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Aged 20-40 years, in good general health
  • I-II
  • Singleton, term (37-41 weeks) pregnancy with normal fetal development
  • Planned for elective cesarean section, no labor

Exclusion criteria

Exclusion Criteria:

  • Pregnancy complications (e.g., severe preeclampsia, gestational diabetes, placental abruption)
  • Major organ dysfunction (heart, liver, kidney) or psychiatric history
  • Allergy to local anesthetics or any study drugs
  • Prior abdominal surgery or infection that may affect block efficacy
  • Coagulation disorders or current anticoagulant use
  • Refusal to participate or inability to comply with follow-up
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

ASA physical status

The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.

05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
83 participants (actual)

Study arms

  • Experimental
    TAP Block Group

    The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg + tropisetron 8 mg);

    Drug: The TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg)

  • No intervention
    the control group

    received only the same formula intravenous analgesia pump. For both groups, rescue

Interventions

  • DrugThe TAP block group received ultrasound-guided bilateral TAP block (20 mL of 0.375 % ropivacaine per side) during surgery and postoperative intravenous analgesia pump (formula of butorphanol 2 mg/kg)

    the control group received only the same formula intravenous analgesia pump

06

What researchers measure

Primary outcomes

  1. VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity ( Time to first rescue analgesia requirement and number of patients and total dosage of flurbiprofen axetil used within 48 hours postoperatively;

    VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity (coughing or turning) at 2, 6, 12, 24, and 48 hours postoperatively were recorded by anesthesiologists not involved in this study.

    Time frame: 5 months

07

Study locations

2 sites
  • Shandong Provincial Maternal and Child Health Care Hospital
    Jinan, Shandong 250014, China
  • Shandong Provincial Maternal and Child Health Care Hospital
    Jinan, Shandong, China
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jun 2025 to primary completion in Oct 2025, 4 months.

Of 2,094 non-industry interventional studies with no phase under Pain, Postoperative, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 23. This study's 4 months is below that.

Counting every sponsor, half of 2,107 studies reached it within 11 months; a quarter within 6 and three quarters within 23.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 7, 2026
First posted
Mar 17, 2026
StartActual
Jun 1, 2025
Primary completionActual
Oct 31, 2025
CompletionActual
Oct 31, 2025
Last update
Mar 17, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07478692
Lead sponsor
Qing Yuan
Responsible party
Qing Yuan (Shandong Provincial Maternal and Child Health Care Hospital, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University) — Sponsor-investigator
First posted
Mar 17, 2026
Start date
Jun 1, 2025
Primary completion
Oct 31, 2025
Completion
Oct 31, 2025
Last update
Mar 17, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.

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