ClinicalTrials.gg
RecruitingNCT07447362CV-RISKUpdated Mar 3, 2026

Clinical Management of Cardiovascular Risk Factors in Adult Patients: A Before-and-After Interventional Study

An interventional study of Structured Cardiovascular Risk Management in Cardiovascular Risk Factors, Hypertension and Dyslipidemia, sponsored by Universidad Católica San Antonio de Murcia. Recruiting at 1 site in Chile. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-03-03.

Sponsored by Universidad Católica San Antonio de Murcia · Not applicable, Interventional, and Prevention

From the registry’s dates

  • Primary completion was expected by Jul 2026, 3 months ago, but the record still lists the study as recruiting.
  • Registered 1 year 7 months after the study started (first participant enrolled Jul 2024, registered Feb 2026).
  • Started Jul 2024; still recruiting 2 years 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
220
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

This study aims to evaluate cardiovascular risk factors, clinical characteristics, and outcomes in adult patients attending an outpatient cardiology clinic. The research focuses on identifying predictors of adverse cardiovascular events, optimizing risk stratification, and improving preventive strategies in routine clinical practice. Data will be collected from patients receiving standard cardiology care without altering their treatment. The results are expected to contribute to better understanding of cardiovascular risk profiles and to support improvements in clinical decision-making and patient management.

02

Conditions studied

  • Cardiovascular Risk Factors
  • Hypertension
  • Dyslipidemia
  • Type 2 Diabetes Mellitus
  • Obesity
  • Overweight
  • Tobacco Use

Keywords

  • Cardiovascular prevention
  • Risk factor control
  • Medication adherence
  • Clinical follow-up
03

In context

Hypertension

6,114 studies on the registry are indexed under Hypertension; 912 are open to participants now.

This study's planned enrollment of 220 is above the median of 100 across 4,575 interventional studies indexed under Hypertension.

Browse Hypertension studies →

Lead sponsor

Universidad Católica San Antonio de Murcia is the lead sponsor of 138 studies on the registry; 18 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age ≥18 years
  • Presence of at least one cardiovascular risk factor (hypertension, diabetes, dyslipidemia, obesity, or smoking)
  • Receiving outpatient clinical follow-up
  • Ability to provide

Exclusion criteria

Exclusion Criteria:

  • Severe clinical instability requiring hospitalization
  • Pregnancy
  • End-stage renal disease or dialysis
  • Inability to complete follow-up visits
  • Refusal to participate
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
220 participants (estimated)

Study arms

  • Experimental
    Structured Clinical Management

    Participants receive structured clinical follow-up with periodic assessment of cardiovascular risk factors and adjustment of pharmacological and lifestyle management according to current clinical guidelines over a 120-day follow-up period.

    Other: Structured Cardiovascular Risk Management

Interventions

  • OtherStructured Cardiovascular Risk Management

    Protocol-based clinical management including periodic evaluation and adjustment of antihypertensive, lipid-lowering, antidiabetic, and lifestyle interventions according to routine clinical practice guidelines.

06

What researchers measure

Primary outcomes

  1. Change in systolic blood pressure

    Change in systolic blood pressure (mmHg) measured under standardized conditions to evaluate the effect of structured clinical and pharmacological cardiovascular risk management.

    Time frame: Baseline to 90 days

Secondary outcomes

  1. Change in diastolic blood pressure

    Evaluation of changes in diastolic blood pressure following structured clinical and pharmacological management.

    Time frame: Baseline to 90 days

  2. Change in LDL cholesterol

    Evaluation of changes in LDL cholesterol measured during routine laboratory assessment after structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  3. Change in HbA1c

    Evaluation of changes in glycated hemoglobin (HbA1c) following structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  4. Change in body weight

    Evaluation of changes in body weight following lifestyle counseling and structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  5. Change in renal function (eGFR)

    Evaluation of changes in renal function assessed by estimated glomerular filtration rate following structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  6. Change in HDL cholesterol

    Evaluation of changes in HDL cholesterol measured during routine laboratory assessment after structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  7. Change in triglycerides

    Evaluation of changes in triglyceride levels measured during routine laboratory assessment after structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  8. Change in total cholesterol

    Evaluation of changes in total cholesterol measured during routine laboratory assessment after structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  9. Change in fasting plasma glucose

    Evaluation of changes in fasting plasma glucose following structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  10. Change in body mass index

    Evaluation of changes in body mass index following lifestyle counseling and structured cardiovascular risk management.

    Time frame: Baseline to 90 days

  11. Change in microalbuminuria

    Evaluation of changes in urinary albumin excretion to assess microalbuminuria during follow-up after structured cardiovascular risk management.

    Time frame: Baseline to 90 days

07

Study locations

1 of 1 sites recruiting
  • CDIEM Medical Center - Outpatient Cardiology Clinic
    Santiago, Santiago Metropolitan, Chile
    Recruiting
    • Julio César Núñez Farías, MD, MSc · Contactllaillai@yahoo.es · +56965860130
    • Julio C Núñez Farías, MD, MSc · Principal investigator
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be shared due to privacy regulations and institutional data protection policies. De-identified aggregated results will be available through scientific publication.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 3, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07447362
Responsible party
Julio Núñez Farías (Cardiologist and Principal Investigator, Universidad Católica San Antonio de Murcia) — Principal investigator
First posted
Mar 3, 2026
Start date
Jul 24, 2024
Primary completion
Jul 24, 2026 (estimated)
Completion
Oct 24, 2026 (estimated)
Last update
Mar 3, 2026

Study contacts

Julio César Núñez Farías, MD, MSc (Cardiology)
Contact
llaillai@yahoo.es
+56965860130
José Abellán Alemán, MD, PhD
study chair · Universidad Católica San Antonio de Murcia

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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