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CompletedNCT07380607Updated Apr 15, 2026

Double Triggering Asynchrony in Mechanically Ventilated Patients.

An observational study in Respiratory Failure, Critical Illness and Mechanical Ventilation, sponsored by Mansoura University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-15.

Sponsored by Mansoura University · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
28
Ages
18 Years and older
Sex
All
01

Study summary

This observational study examined double triggering asynchrony in28ICU patients on mechanical ventilation. Researchers collected data on patient characteristics, health conditions, and outcomes to understand how this problem affects critically ill patients. Findings may help improve ventilator care in intensive care units.

02

Conditions studied

  • Respiratory Failure
  • Critical Illness
  • Mechanical Ventilation

Keywords

  • Double Triggering
  • Patient-Ventilator Asynchrony
  • Diaphragmatic Ultrasound
  • Mechanical Ventilation
03

In context

Respiratory Insufficiency

1,650 studies on the registry are indexed under Respiratory Insufficiency; 296 are open to participants now.

This study's enrollment of 28 is below the median of 100 across 545 observational studies indexed under Respiratory Insufficiency.

Browse Respiratory Insufficiency studies →

Lead sponsor

Mansoura University is the lead sponsor of 1,077 studies on the registry; 183 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult patients (>18 years) admitted to medical/surgical ICU at Specialized Medical Hospital, Mansoura University, receiving invasive mechanical ventilation with documented double triggering asynchrony on ventilator waveform analysis.

Inclusion criteria

  • Adult ICU patients aged ≥18 years receiving invasive mechanical ventilation
  • Documented double triggering asynchrony on ventilator waveform analysis.

Exclusion criteria

Exclusion Criteria:

  • Patients with contraindications to diaphragmatic ultrasound, including thoracic or abdominal surgery.
  • Patients with known diseases affecting diaphragmatic function, such as Duchenne muscular dystrophy (DMD) or myasthenia gravis (MG).
  • Patients with advanced chronic liver disease (Child-Pugh class C)
  • Patients with chronic increased intra-abdominal pressure.
  • Patients with moderate to massive pleural effusion.
  • Patient or legal guardian refusal to participate in the study.
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
28 participants (actual)
Patient registry
No

Groups and cohorts

  • Double Triggering Cohort

    28mechanically ventilated ICU patients identified with double triggering asynchrony

06

What researchers measure

Primary outcomes

  1. Sensitivity of diaphragmatic ultrasound for detection of double triggering asynchrony

    Proportion of double triggering asynchrony events correctly identified by diaphragmatic ultrasound compared with ventilator waveform analysis as the reference standard

    Time frame: During ICU admission, at the time of double triggering detection by ventilator graph interpretation

07

Study locations

1 site
  • Specialised Medical Hospital - ICU
    Al Mansurah, Dakahlia Governorate 35516, Egypt
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 15, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07380607
Lead sponsor
Mansoura University
Responsible party
Sponsor
First posted
Feb 2, 2026
Start date
Nov 5, 2024
Primary completion
Oct 20, 2025
Completion
Nov 2, 2025
Last update
Apr 15, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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