CClinicalTrials.gg
Not yet recruitingNCT07857278HPV VaccineUpdated Oct 5, 2026

Web-based Health Education on Information, Motivation, Behavioral Skills Related to Human Papilloma Virus Vaccination

An interventional study of Web-based IMB education delivered as daily modules in Web Based Intervention, sponsored by Mansoura University. Not yet recruiting. Open to female participants aged 18 Years to 22 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-05.

Sponsored by Mansoura University · Not applicable, Interventional, and Prevention

Updated Oct 5, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
340
Allocation
Not applicable
Ages
18 Years to 22 Years
Sex
Female
01

Study summary

This study aims to evaluate the effect of web-based health education on information, motivation, behavioral skills related to human papilloma virus vaccination among female University students Research hypothesis

  • Female University students who receive web based education are expected to improve information about human papilloma virus vaccination more than control group.
  • Female University students who receive web based education are expected to exhibit greater motivation compared with the control group.
  • Female University students who receive web based education are expected to demonstrate greater behavioral skills compared with the control group.
Read the detailed description

In Egypt, cervical cancer is the 13th most prevalent cancer among women and the 9th most common cancer among women aged 15 to 44 years . In 2020, an estimated 1,320 new cases and 744 deaths due to cervical cancer were reported. A national screening program conducted in 2002 assessed the prevalence and risk factors of pre-invasive and invasive cervical cancer among 5,453 women aged 35 to 60 years, revealing prevalence rates of 0.5% for pre-invasive high-grade lesions and 0.04% for invasive cervical cancer . Currently, Egypt does not have a structured nationwide cervical cancer screening program; screening largely depends on women's perceptions and their healthcare providers' recommendations. Evidence indicates that healthcare provider recommendations are a critical factor in promoting screening adherence. Recently, Egypt has launched initiatives in selected governorates to raise awareness about early detection and HPV vaccination. However, the knowledge, attitudes, and practices of Egyptian women regarding cervical cancer screening at the national level remain largely unknown .

Improving information, motivation, and behavioral skills related to HPV vaccination among university students addresses this critical public health gap. By targeting future nurses, this study aims to enhance preventive health practices and contribute to reducing HPV-related infections and cervical cancer incidence. Nursing students play a pivotal role in health promotion and disease prevention. Strengthening their information, motivation, and behavioral skills equips them to educate peers, patients, and the broader community about HPV infection and vaccination. By empowering nurses with evidence-based knowledge and practical skills, this study supports the development of a workforce capable of positively influencing vaccination behaviors and public health outcomes.

The use of web-based education, guided by the Information-Motivation-Behavioral Skills (IMB) model, offers a flexible, cost-effective, and accessible approach to learning. Web-based interventions can reach large groups efficiently, provide tailored content, and facilitate skill-building in diverse populations. The findings from this study can guide health policy, and shape future educational strategies to improve HPV vaccine coverage and preventive health behaviors among young adults.

02

Conditions studied

  • Web Based Intervention
03

In context

Lead sponsor

Mansoura University is the lead sponsor of 1,077 studies on the registry; 183 are open to participants now.

Of its 9 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 22 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • - Females 18 years of age and more.
  • first-year undergraduates
  • No vaccination contraindications.
  • Female undergraduate university students from different faculties.
  • Can use a digital device (smartphone, personal computer, laptop, or tablet).
  • An active email address is required, as all reminders will be sent via email.

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
340 participants (estimated)

Study arms

  • Experimental
    Non-HPV popular science content

    Non-HPV popular science content

    Behavioral: Web-based IMB education delivered as daily modules

Interventions

  • BehavioralWeb-based IMB education delivered as daily modules

    Web-based IMB education delivered as daily modules

06

What researchers measure

Primary outcomes

  1. Tool II: information, motivation, and behavioral skills regarding HPV vaccination adopted from (wang et al.,2023) to assess information, motivation, and behavioral skills of students regarding HPV vaccination includes three parts. Part one: female unive

    Tool II: information, motivation, and behavioral skills regarding HPV vaccination adopted from (wang et al.,2023) to assess information, motivation, and behavioral skills of students regarding HPV vaccination includes three parts. Part one: female university students' information concerning human papillomavirus consist of 11 item such as: HPV is related to the development of cervical cancer, HPV is almost asymptomatic HPV is very common , etc Scoring system: the answers were "Agree," "Disagree," or "I do not know. Each correct answer scored 1 point, while incorrect or unknown answers scored 0 points. The total score of the information questions was derived by adding the number of correct responses. The higher score indicate better information. Part II: Female university students Motivation for vaccination: It includes 5 dimensions with a total of 19 items: perceived susceptibility (2 items), perceived severity (4 items), perceived benefits (3 items) and barriers (5 items), and sub

    Time frame: immediately and after 3 months

Secondary outcomes

  1. Web-based platform evaluation form:including four domains: accessibility and usability, functionality and content quality, technical support and reliability and user satisfaction. Scoring system: answer for these items will be measure on 3- point Likert

    Tool III: Web-based platform evaluation form: It was developed by researcher to assess female university students' feedback about the web-based platform including four domains: accessibility and usability, functionality and content quality, technical support and reliability and user satisfaction.

    Time frame: immediately after intervention

  2. Web-based platform evaluation form:including four domains: accessibility and usability, functionality and content quality, technical support and reliability and user satisfaction. Scoring system: answer for these items will be measure on 3- point Likert

    Time frame: immediately after intervention

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Gause G, Mokgaola IO, Rakhudu MA. Information technology for teaching and learning in a multi-campus public nursing college. Health SA. 2022 May 12;27:1828. doi: 10.4102/hsag.v27i0.1828. eCollection 2022. PubMed 35747508 ↗
  • el-All HS, Refaat A, Dandash K. Prevalence of cervical neoplastic lesions and Human Papilloma Virus infection in Egypt: National Cervical Cancer Screening Project. Infect Agent Cancer. 2007 Jul 4;2:12. doi: 10.1186/1750-9378-2-12. PubMed 17610742 ↗
  • Behery MB, Bahbah AA, Mohamed Shawqi M, El-Said YM, Sherif LN, Ataallah HA, Adwy ES, Ageez RE, Helmi Abo Elwafa A, Ahmed NMB, Elsaadany R, El-Bary NA. Knowledge, attitude, and practice towards uterine cervical cancer screening in Egyptian females: a nationwide cross-sectional study. BMC Cancer. 2025 Feb 11;25(1):237. doi: 10.1186/s12885-025-13530-4. PubMed 39934731 ↗
  • Aggarwal S, Agarwal P, Singh AK. Human papilloma virus vaccines: A comprehensive narrative review. Cancer Treat Res Commun. 2023;37:100780. doi: 10.1016/j.ctarc.2023.100780. Epub 2023 Nov 21. PubMed 38006748 ↗

Related links

Individual participant data

Plan to share: Undecided

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 5, 2026
Show all 1 update
  1. Oct 5, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07857278
Lead sponsor
Mansoura University
Responsible party
Nehmedo Ezzat osman (Assistant professor, Mansoura University) — Principal investigator
First posted
Oct 5, 2026
Start date
Oct 1, 2026 (estimated)
Primary completion
Dec 1, 2026 (estimated)
Completion
Jan 1, 2027 (estimated)
Last update
Oct 5, 2026

Study contacts

Nehmedo Ezzat Osman, Assisstant professor
Contact
nehmedo@mans.edu.eg
01011301978

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion