An interventional study of Nano-Learning interventional program in Learning; Lack of (Specific), Depression and Older Adults, sponsored by Alexandria University. Active, not recruiting at 1 site in Egypt. Open to participants aged 58 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-09-22.
Sponsored by Alexandria University · Not applicable, Interventional, and Supportive care
Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.
Nanolearning is an innovative pedagogical strategy that delivers content in highly focused, ultra-short learning experiences, often lasting less than two minutes, aimed at teaching a single skill or topic . Typically offered digitally through bite-sized video lessons or interactive practice exercises, it capitalizes on learners' preference for short-form content and informal learning methods, making knowledge acquisition more accessible and manageable for busy individuals. A defining feature of nano-learning is its brevity, with lessons intentionally kept under two minutes to align with contemporary learning habits, such as engaging with short-form videos on platforms like YouTube Shorts and TikTok . Empirical evidence suggests that the use of short videos is associated with decreased feelings of loneliness and social isolation, thereby reducing depression among older adults . Platforms that allow users to showcase aspects of their own lives also serve as a significant avenue for achieving "happiness in old age" and enhancing social interactions with acquaintances . Therefore, this study aims to provide robust evidence on the effectiveness of nano-learning interventions, particularly in the context of sarcopenia, where addressing physical and psychological well-being has become increasingly critical among this cohort.
8,057 studies on the registry are indexed under Depression; 1,641 are open to participants now.
This study's planned enrollment of 180 is above the median of 84 across 6,720 interventional studies indexed under Depression.
Browse Depression studies →Alexandria University is the lead sponsor of 569 studies on the registry; 125 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
• Recruitment was conducted through face-to-face interviews in the clinic's waiting areas by the research team. These initial meetings, lasting approximately 20-30 minutes per participant, were essential for building rapport, obtaining anthropometric and other objective data, and ensuring informed consent. During the interview, the researchers explained the purpose and procedures of the study in detail, collected participants' mobile phone numbers, and administered the baseline (pretest) assessment using the study tools.
Behavioral: Nano-Learning interventional program
they will be exposed only to the routine care provided by the nursing homes.
AI-based Nano-learning videos involves designing ultra-short, single-focus lessons (not exceeding 2 minutes). Each session was delivered in form of some videos.
A Composite Physical Function (CPF) Scale
is a validated tool designed to assess functional capacity in older adults across a continuum of daily activities. It consists of 12 items organized hierarchically, beginning with two basic activities of daily living (BADL) related to self-care, eating, and hygiene, followed by eight instrumental activities of daily living (IADL) that assess community functioning such as household chores, shopping, and mobility, and concluded with two advanced activities involving more demanding household tasks and strenuous physical exercise.
Time frame: 2 month
Mini Nutritional Assessment-Short Form (MNA-SF)
is a validated screening tool and one of the most widely recognized and well-studied tools for nutritional screening. It is designed to quickly identify older adults who are malnourished or at risk of malnutrition. As a shortened version of the full Mini Nutritional Assessment, it is widely used in clinical, community, and research settings due to its simplicity and time efficiency (Vellas et al., 2006).
Time frame: 2 month
Geriatric Depression Scale-Short Form (GDS-SF)
is a 15-item self-report tool designed to evaluate depression and overall well-being in older adults. Respondents indicate how they have felt during the past week by choosing either "Yes" (scored as 1) or "No" (scored as 0). Scores are summed to yield a total ranging from 0 to 15, with 0-4 reflecting no depression, 5-8 indicating mild depression, 9-11 suggesting moderate depression, and 12-15 representing severe depression. In 2013, Elhusseini translated the scale into Arabic, confirming its validity and reliability (r = 0.70). The GDS-SF remains one of the most effective and widely used geriatric-specific screening instruments for detecting depression in older adults (Abd El Fatah et al., 2022; Stone et al., 2019).
Time frame: 2 month
This study is active, not recruiting, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Alexandria University