ClinicalTrials.gg
CompletedNCT06838156Updated Feb 20, 2025

Comparison of Analgesic Efficacy of Quadratus Lumborum Type 3 and Suprainguinal Fascia Iliaca Compartment Block in Total Hip Arthroplasty Surgery

An interventional study of Bupivacain and Bupivacain in Opioid Consumption and Pain Postoperative, sponsored by Başakşehir Çam & Sakura City Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-02-20.

Sponsored by Başakşehir Çam & Sakura City Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 11 months after the study started (first participant enrolled Feb 2023, registered Feb 2025).
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years and older
Sex
All
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Study summary

Total Hip Arthroplasty (THA) is a complex surgical procedure frequently performed to treat degenerative conditions in the hip joint. As people's life expectancy increases, the need for hip arthroplasty increases. İnvestigetors aimed to compare the analgesic properties of SIFI and QLB blocks.

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Conditions studied

  • Opioid Consumption
  • Pain Postoperative

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In context

Pain, Postoperative

5,227 studies on the registry are indexed under Pain, Postoperative; 1,154 are open to participants now.

This study's enrollment of 60 is below the median of 75 across 4,457 interventional studies indexed under Pain, Postoperative.

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Lead sponsor

Başakşehir Çam & Sakura City Hospital is the lead sponsor of 107 studies on the registry; 35 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Elective patients scheduled for hip arthroplasty surgery
  2. Patient willingness to participate in the study
  3. Patients over 18 years age of, ASA I-II-III,

Exclusion criteria

Exclusion Criteria:

  1. Patients not wanting to participate in the study
  2. Patients who do not want regional anesthesia technique
  3. Allergic or coagulated patients
  4. Patients with liver, kidney, lung, heart failure and septic patients
  5. Neurological disorder, history of convulsions
  6. ASA IV patients
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Care provider)
Enrollment
60 participants (actual)

Study arms

  • Active comparator
    SIFI Group

    Group of 30 patients who underwent SIFI block

    Drug: Bupivacain

  • Active comparator
    QLB Type 3

    Group of 30 patients who underwent QLB block

    Drug: Bupivacain

Interventions

  • Suprainguinal Fascia Iliaca Compartment block was performed with a linear probe placed over the inguinal ligament using a portable ultrasound device. After visualization of the femoral nerve, 30 ml of 0.25% bupivacaine was injected into the fascia iliaca overlying the iliopsoas muscle using an appropriate needle.

    Also known as: SIFI

  • Quadratus Lumborum Type 3 block was performed using a portable ultrasound device with a linear probe placed between the costal margin and the iliac crest on the lateral abdominal wall. 30 ml of 0.25% bupivacaine was injected between the quadratus lumborum and psoas muscles using an appropriate needle.

    Also known as: QLB Type 3

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What researchers measure

Primary outcomes

  1. Effect on pain score

    Postoperative 24-hour Visual Analog Scale was measured. ( 0=best 10=worst)

    Time frame: At 1,2,4, 6, 12 and 24 hours after surgery

Secondary outcomes

  1. Opioid Consumption

    Intravenous patient-controlled analgesia (PCA) with tramadol was administered to both groups in the postoperative period.

    Time frame: At 1,2,4, 6, 12 and 24 hours after surgery

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Study locations

1 site
  • Başakşehir Çam Ve Sakura City Hospital
    Başakşehir, Istanbul, Turkey (Türkiye)
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References and documents

Publications

  • Safa B, Trinh H, Lansdown A, McHardy PG, Gollish J, Kiss A, Kaustov L, Choi S. Ultrasound-guided suprainguinal fascia iliaca compartment block and early postoperative analgesia after total hip arthroplasty: a randomised controlled trial. Br J Anaesth. 2024 Jul;133(1):146-151. doi: 10.1016/j.bja.2024.04.019. Epub 2024 May 18. PubMed 38762396 ↗
  • Xia Q, Ding W, Lin C, Xia J, Xu Y, Jia M. Postoperative pain treatment with transmuscular quadratus lumborum block and fascia iliaca compartment block in patients undergoing total hip arthroplasty: a randomized controlled trial. BMC Anesthesiol. 2021 Jul 10;21(1):188. doi: 10.1186/s12871-021-01413-7. PubMed 34243719 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 20, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06838156
Responsible party
Muzaffer GENCER (Associate Professor Doctor, Başakşehir Çam & Sakura City Hospital) — Principal investigator
First posted
Feb 20, 2025
Start date
Feb 15, 2023
Primary completion
Jun 15, 2023
Completion
Aug 1, 2023
Last update
Feb 20, 2025

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.

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Studies of the drug tested here: Bupivacaine

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