A Phase 2/3 interventional study of Gabapentin and Placebo in Pain, Postoperative, sponsored by University of California, Davis. Recruiting at 1 site in United States. Open to participants aged Up to 17 Years. Per ClinicalTrials.gov, last updated 2025-10-31.
Sponsored by University of California, Davis · Phase 2/3, Interventional, and Treatment
The primary objective of this study is to determine if the peri and post operative use of gabapentin in children reduces the need for narcotics after thoracic surgery.
We hypothesize that patients who are given gabapentin will need fewer morphine equivalents postoperatively than those who were not given gabapentin
This study is a double-blind, placebo controlled, randomized study to explore the effects of gabapentin peri and post operatively. Physician and families will be blinded to the treatment.
60 subjects will be randomized in a 1:1 ratio to either:
We aim to understand the impact that gabapentin use peri and post operatively has on:
The duration of an individual subject's participation in the study will be 7 days or until the patient is discharged from UC Davis Hospital, whichever occurs first.
5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.
This study's planned enrollment of 60 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →University of California, Davis is the lead sponsor of 798 studies on the registry; 146 are open to participants now.
Of its 65 completed or terminated interventional studies of FDA-regulated products, 43 (66%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Given at a dose of 10mg/kg (max 600mg) perioperatively (immediately prior to surgery) followed by 3mg/kg/dose TID with first dose to be given starting at 8 hours post perioperative dose.
Drug: Gabapentin
Given placebo which coincides with the active treatment group
Other: Placebo
Determine if the peri and post operative use of gabapentin in children reduces the need for narcotics after surgery.
Control Arm
Amount of pain medication needed.
Amount of pain medication needed after surgery
Time frame: 7 days post-operative or until discharge, whichever came first
Plan to share: No
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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University of California, Davis