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CompletedNCT06657287Updated Oct 24, 2024

Postprandial Hypotension and Insulin Levels

An observational study in Postprandial Hypotension and Hypoglycemia, sponsored by Ankara Yildirim Beyazıt University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-10-24.

Sponsored by Ankara Yildirim Beyazıt University · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
111
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The goal of this observational study is to learn about the relationship between postprandial hypotension and insulin levels in adults. The main question it aims to answer is:

Is the incidence of postprandial hypotension high in patients who undergo mixed meal test?

Is insulin level higher in individuals with postprandial hypotension compared to those without during a mixed meal test?

Patients with postprandial symptoms were scheduled for a mixed meal test, during which plasma glucose, insulin, C-peptide, blood pressure, and heart rate were measured at specific time points.

02

Conditions studied

  • Postprandial Hypotension
  • Hypoglycemia

Keywords

  • Hypotension
  • hypoglycemia
  • insulin
  • mixed meal
  • adults
  • postprandial
03

In context

Hypoglycemia

654 studies on the registry are indexed under Hypoglycemia; 86 are open to participants now.

This study's enrollment of 111 is above the median of 85 across 137 observational studies indexed under Hypoglycemia.

Browse Hypoglycemia studies →

Lead sponsor

Ankara Yildirim Beyazıt University is the lead sponsor of 238 studies on the registry; 55 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Patients who apply to the Endocrinology Clinic of Ankara Bilkent City Hospital.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adults with postprandial symptoms

Exclusion criteria

Exclusion Criteria:

  • Individuals with prediabetes or diabetes,
  • Those aged 65 and above,
  • Patients using antihypertensive medications or with known hypertension,
  • Those with active infections,
  • Congestive heart failure,
  • Peripheral artery disease,
  • Advanced-stage dementia,
  • Individuals who could not provide a history or were unable to cooperate,
  • Patients using medications that could induce hypoglycemia (oral antidiabetics, insulin, beta-blockers, hydroxychloroquine, bromocriptine, etc.)
  • Those with conditions that could cause hypoglycemia (uncontrolled hypothyroidism, adrenal insufficiency, growth hormone deficiency, etc.)
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
111 participants (actual)
Target follow-up
1 Day
Patient registry
Yes

Groups and cohorts

  • Healthy adults

    Adults with postprandial symptoms

    Other: Mixed meal test

Interventions

  • OtherMixed meal test

    The biochemical parameters, blood pressure, and heart rates of participants undergoing the mixed meal test will be recorded over a 5-hour period.

06

What researchers measure

Primary outcomes

  1. Systolic blood pressure

    mmHg

    Time frame: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)

  2. Blood glucose

    mg/dL

    Time frame: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)

  3. Blood insulin

    uIU/mL

    Time frame: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)

Secondary outcomes

  1. Blood C-peptide

    ng/mL

    Time frame: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)

  2. Diastolic blood pressure

    mmHg

    Time frame: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)

  3. Heart rate

    bpm

    Time frame: During mixed meal test (baseline, 30., 60., 90., 120., 180., 240., 300. min)

07

Study locations

1 site
  • Ankara Bilkent City Hospital
    Ankara, Çankaya 06800, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 24, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06657287
Responsible party
Rahime Evra KARAKAYA (Principal Investigator, Ankara Yildirim Beyazıt University) — Principal investigator
First posted
Oct 24, 2024
Start date
Apr 3, 2024
Primary completion
Sep 1, 2024
Completion
Sep 1, 2024
Last update
Oct 24, 2024

Study contacts

Rahime E Karakaya, PhD
principal investigator · Ankara Yildirim Beyazıt University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Oct 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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