An observational study in COPD, Obesity and Chronic Obstructive Pulmonary Disease, sponsored by Rijnstate Hospital. Completed at 1 site in Netherlands. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2024-06-26.
Sponsored by Rijnstate Hospital · Observational
The purpose of this study is to investigate whether obese COPD patients experience more or less discomfort in daily life. Furthermore the investigators will evaluate if body composition or body fat distribution has effects on symptoms and performance.
Chronic Obstructive Pulmonary Disease (COPD) and Obesity are two major health problems. The prevalence of both is growing and there is a complex interaction between COPD and obesity. On the one hand obesity impairs lung function, with decreasing static lung volumes being the most significant effect. On the other hand there seems a beneficial role of obesity on lung function in COPD patients. This is because obese COPD patients tend to have less hyperinflation than non-obese COPD patients . An interesting question is what the net effect of these changes in lung function is on respiratory symptoms and quality of life.
In this observational study, the investigators will compare obese and non-obese COPD patients. Pulmonary function, dyspnea and quality of life will be compared between the two groups.
3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.
This study's enrollment of 166 is close to the median of 157 across 929 observational studies indexed under Lung Diseases.
Browse Lung Diseases studies →Rijnstate Hospital is the lead sponsor of 127 studies on the registry; 14 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients with a diagnosis of COPD who visit a Pulmonologist at Rijnstate Hospital.
Exclusion Criteria:
COPD patients with BMI 18.5-24.99
COPD patients with BMI ≥ 30
Dyspnoea - mMRC
Level of dyspnoea perceived in daily life measured using the Modified Medical Research Council (mMRC) dyspnoea scale. The mMRC dyspnoea scale ranges from grade 0 to 4. Higher scores mean a worse outcome.
Time frame: At inclusion
Dyspnoea - NCSI
Level of dyspnoea perceived in daily life measured using the Nijmegen Clinical Screening Instrument (NCSI). The NCSI ranges from grade 0 to 11. Higher scores mean a worse outcome.
Time frame: At inclusion
Change in dyspnoea
Level of dyspnoea using the Borg score. The Borg score ranges from grade 0 to 10. Higher scores mean a worse outcome.
Time frame: Before and after the 6 minute walking test
6 minute walking test
distance walked in 6 minutes measured in metres
Time frame: At inclusion
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.
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Rijnstate Hospital