An observational study in Coronary Artery Disease, Arrhythmias, Cardiac and Heart Valve Diseases, sponsored by First Affiliated Hospital Xi'an Jiaotong University. Recruiting at 1 site in China. Open to participants aged 3 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-07-12.
Sponsored by First Affiliated Hospital Xi'an Jiaotong University · Observational
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.
Cardiovascular and cerebrovascular diseases refer to ischemic and hemorrhagic diseases of the heart, brain and body tissues caused by hyperlipidemia, blood viscosity, atherosclerosis, hypertension, etc. It is one of the major public health problems in the world. The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.
Patients with cardiovascular and cerebrovascular diseases will be recruited, including coronary artery disease, arrhythmia, heart valve disease, aortic dissection, cardiac masses, myocarditis, hypertension, cardiomyopathy, structural heart disease, ischemic cerebrovascular disease, hemorrhagic cerebrovascular disease, and intracranial space occupying lesion.
Exclusion Criteria:
Diagnosis of coronary artery disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of arrhythmia by clinical guidelines. by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of heart valve disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of aortic dissection by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of cardiac messes by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of myocarditis by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of hypertension by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of cardiomyopathy by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of structural heart disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of ischemic cerebrovascular disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of hemorrhagic cerebrovascular disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of intracranial space occupying by clinical guidelines.
Other: Observational; No Interventions were given.
Observational; No Interventions were given.
Change of MACCE
Major adverse cardiovascular and cerebrovascular events, a composite of all-cause mortality, myocardial infarction, coronary revascularization, and stroke.
Time frame: Through study completion, up to 5 years.
Change of all-cause mortality
Incidence of patients' death from any cause.
Time frame: Through study completion, up to 5 years.
Incidence of myocardial infarction
Changes of serum myocardial zymogram level and ECG were used for diagnosing of myocardial infarction.
Time frame: Through study completion, up to 5 years.
Incidence of coronary revascularization.
Incidence of percutaneous coronary intervention or coronary artery bypass grafting.
Time frame: Through study completion, up to 5 years.
Incidence of stroke
Stroke were assessed by radiologist using CT scan or other imaging test.
Time frame: Through study completion, up to 5 years.
Plan to share: No
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First Affiliated Hospital Xi'an Jiaotong University