An observational study in Coronary Artery Disease, Arrhythmias, Cardiac and Heart Valve Diseases, sponsored by First Affiliated Hospital Xi'an Jiaotong University. Recruiting at 1 site in China. Open to participants aged 3 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-07-12.
Sponsored by First Affiliated Hospital Xi'an Jiaotong University · Observational
The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.
Cardiovascular and cerebrovascular diseases refer to ischemic and hemorrhagic diseases of the heart, brain and body tissues caused by hyperlipidemia, blood viscosity, atherosclerosis, hypertension, etc. It is one of the major public health problems in the world. The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.
4,857 studies on the registry are indexed under Coronary Artery Disease; 890 are open to participants now.
This study's planned enrollment of 25,000 is above the median of 320 across 1,687 observational studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →First Affiliated Hospital Xi'an Jiaotong University is the lead sponsor of 314 studies on the registry; 87 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with cardiovascular and cerebrovascular diseases will be recruited, including coronary artery disease, arrhythmia, heart valve disease, aortic dissection, cardiac masses, myocarditis, hypertension, cardiomyopathy, structural heart disease, ischemic cerebrovascular disease, hemorrhagic cerebrovascular disease, and intracranial space occupying lesion.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Diagnosis of coronary artery disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of arrhythmia by clinical guidelines. by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of heart valve disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of aortic dissection by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of cardiac messes by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of myocarditis by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of hypertension by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of cardiomyopathy by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of structural heart disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of ischemic cerebrovascular disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of hemorrhagic cerebrovascular disease by clinical guidelines.
Other: Observational; No Interventions were given.
Diagnosis of intracranial space occupying by clinical guidelines.
Other: Observational; No Interventions were given.
Observational; No Interventions were given.
Change of MACCE
Major adverse cardiovascular and cerebrovascular events, a composite of all-cause mortality, myocardial infarction, coronary revascularization, and stroke.
Time frame: Through study completion, up to 5 years.
Change of all-cause mortality
Incidence of patients' death from any cause.
Time frame: Through study completion, up to 5 years.
Incidence of myocardial infarction
Changes of serum myocardial zymogram level and ECG were used for diagnosing of myocardial infarction.
Time frame: Through study completion, up to 5 years.
Incidence of coronary revascularization.
Incidence of percutaneous coronary intervention or coronary artery bypass grafting.
Time frame: Through study completion, up to 5 years.
Incidence of stroke
Stroke were assessed by radiologist using CT scan or other imaging test.
Time frame: Through study completion, up to 5 years.
Plan to share: No
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First Affiliated Hospital Xi'an Jiaotong University →